Selected Publications

Academic Article

Year Title Altmetric
2018 Enhanced Sensitivity of Patient-Derived Pediatric High-Grade Brain Tumor Xenografts to Oncolytic HSV-1 Virotherapy Correlates with Nectin-1 ExpressionScientific Reports.  8. 2018
2018 FTY720 Decreases Tumorigenesis in Group 3 Medulloblastoma Patient-Derived XenograftsScientific Reports.  8. 2018
2018 UAB30, a novel RXR agonist, decreases tumorigenesis and leptomeningeal disease in group 3 medulloblastoma patient-derived xenograftsJournal of Neuro-Oncology.  140:209-224. 2018
2018 The Impact of Early Corticosteroid Pretreatment Before Initiation of Chemotherapy in Patients With Primary Central Nervous System Lymphoma.Neurosurgery2018
2018 Quality Initiative to Improve time to Antibiotics for Febrile Pediatric Patients with Potential Neutropenia.Pediatric Quality and Safety.  3:e095. 2018
2018 Drugging SUMOylation for neuroprotection and oncotherapyNeural Regeneration Research.  13:415-416. 2018
2018 Cerebral ischemia increases small ubiquitin-like modifier conjugation within human penumbral tissue: Radiological-pathological correlationFrontiers in Neurology.  8. 2018
2017 Newly Characterized Murine Undifferentiated Sarcoma Models Sensitive to Virotherapy with Oncolytic HSV-1 M002Molecular Therapy - Oncolytics.  7:27-36. 2017
2017 Complete durable response of a pediatric anaplastic oligodendroglioma to temozolomide alone: Case report and review of literatureMedical and Pediatric Oncology.  64. 2017
2017 Publication outcomes of abstracts from the American Society of Hematology Annual MeetingAmerican Journal of Hematology.  92:E81-E83. 2017
2017 Oncolytic Virotherapy for the Treatment of Malignant GliomaNeurotherapeutics.  14:333-344. 2017
2017 Rationale and Design of a Phase 1 Clinical Trial to Evaluate HSV G207 Alone or with a Single Radiation Dose in Children with Progressive or Recurrent Malignant Supratentorial Brain TumorsHuman Gene Therapy Clinical Development.  28:7-16. 2017
2017 Checkpoint proteins in pediatric brain and extracranial solid tumors: Opportunities for immunotherapyClinical Cancer Research.  23:342-350. 2017
2017 Combination strategies enhance oncolytic virotherapyOncotarget.  8:34020-34021. 2017
2016 Protocol for Reducing Time to Antibiotics in Pediatric Patients Presenting to an Emergency Department with Feer and Neutropenia: Efficacy and BarriersPediatric Emergency Care.  32:739-745. 2016
2016 Effect of repeat dosing of engineered oncolytic herpes simplex virus on preclinical models of rhabdomyosarcomaTranslational Oncology.  9:419-430. 2016
2016 Pediatric medulloblastoma xenografts including molecular subgroup 3 and CD133+ and CD15+ cells are sensitive to killing by oncolytic herpes simplex virusesNeuro-Oncology.  18:227-235. 2016
2016 Oncolytic virotherapy for pediatric malignancies: future prospects.Oncolytic Virotherapy.  5:73-80. 2016
2015 Pediatric cancer gone viral. Part I: Strategies for utilizing oncolytic herpes simplex virus-1 in childrenMolecular Therapy - Oncolytics.  2:15015. 2015
2015 Pediatric cancer gone viral. Part II: Potential clinical application of oncolytic herpes simplex virus-1 in childrenMolecular Therapy - Oncolytics.  2:15016. 2015
2015 Prolonged treatment with bevacizumab is associated with brain atrophy: a pilot study in patients with high-grade gliomasJournal of Neuro-Oncology.  122:585-593. 2015
2015 Attack of the cancer-killing viruses: Clinical application of oncolytic virotherapy in childrenMedical and Pediatric Oncology.  62:739-740. 2015
2015 γ 1 34.5-deleted HSV-1-expressing human cytomegalovirus IRS1 gene kills human glioblastoma cells as efficiently as wild-type HSV-1 in normoxia or hypoxiaGene Therapy.  22:348-355. 2015
2014 Oncolytic viral therapy: targeting cancer stem cells.Oncolytic Virotherapy.  2014:21-33. 2014
2014 Preclinical evaluation of engineered oncolytic herpes simplex virus for the treatment of pediatric solid tumorsPLoS ONE.  9. 2014
2014 Expression of PRMT5 correlates with malignant grade in gliomas and plays a pivotal role in tumor growth in vitroJournal of Neuro-Oncology.  118:61-72. 2014
2014 The role of Src family kinases in growth and migration of glioma stem cellsInternational Journal of Oncology.  45:302-310. 2014
2013 Pediatric glioma stem cells: Biologic strategies for oncolytic HSV virotherapyFrontiers in Oncology.  3 FEB. 2013
2013 Preclinical Evaluation of Engineered Oncolytic Herpes Simplex Virus for the Treatment of NeuroblastomaPLoS ONE.  8. 2013
2013 Treatment of children with glioblastoma with conformal radiation, temozolomide, and bevacizumab as adjuncts to surgical resectionJournal of Pediatric Hematology/Oncology.  35. 2013
2013 CD133 marks a myogenically primitive subpopulation in rhabdomyosarcoma cell lines that are relatively chemoresistant but sensitive to mutant HSVMedical and Pediatric Oncology.  60:45-52. 2013
2012 Hypoxia moderates γ134.5-deleted herpes simplex virus oncolytic activity in human glioma xenoline primary culturesTranslational Oncology.  5:200-207. 2012
2012 Targeting pediatric cancer stem cells with oncolytic virotherapy.Pediatric Research.  71:500-510. 2012
2011 Response to radiation in renal medullary carcinomaRare Tumors.  3:100-103. 2011
2011 Long-term complete response after treatment with cytarabine, vincristine, and prednisone in an infant with refractory multisystem Langerhans cell histiocytosisMedical and Pediatric Oncology.  57:180-181. 2011
2011 Cancer stem cells and pediatric solid tumorsCancers.  3:298-318. 2011
2010 Complete response to carboplatin, gemcitabine, and paclitaxel in a patient with advanced metastatic renal medullary carcinomaMedical and Pediatric Oncology.  55:1217-1220. 2010
2009 Engineered herpes simplex viruses efficiently infect and kill CD133+ human glioma xenograft cells that express CD111Journal of Neuro-Oncology.  95:199-209. 2009
2009 Herpes simplex virus oncolytic therapy for pediatric malignanciesMolecular Therapy.  17:1125-1135. 2009
2008 Myelofibrosis in a patient with familial hemophagocytic lymphohistiocytosisMedical and Pediatric Oncology.  50:1260-1262. 2008
2007 Changing trends of research and treatment in infant neuroblastomaMedical and Pediatric Oncology.  49:1060-1065. 2007

Education And Training

  • Doctor of Medicine, Medical College of Georgia 2002
  • UAB Hospital, Internship 2003
  • UAB Hospital, Residency 2005
  • UAB Hospital, Postdoctoral Fellowship 2008
  • Full Name

  • Gregory Friedman