Positions

Selected Publications

Academic Article

Year Title Altmetric
2019 Longitudinal assessment of anchored transponder migration following lung stereotactic body radiation therapy.Journal of Applied Clinical Medical Physics.  20:17-22. 2019
2018 Radiotherapy plus cetuximab or cisplatin in human papillomavirus-positive oropharyngeal cancer (NRG Oncology RTOG 1016): a randomised, multicentre, non-inferiority trial.Lancet.  393:40-50. 2018
2018 First-Line Treatment of Widely Metastatic BRAF-Mutated Salivary Duct Carcinoma With Combined BRAF and MEK Inhibition.Journal of the National Comprehensive Cancer Network.  16:1166-1170. 2018
2018 Spindle Epithelial Tumor with Thymus-Like Differentiation (SETTLE): A Next-Generation Sequencing Study.Head and Neck Pathology2018
2018 Head and Neck Cancers: Advantages of Advanced Radiation Therapy and Importance of Supportive Care.Journal of the National Comprehensive Cancer Network.  16:666-669. 2018
2018 NCCN Guidelines Insights: Head and Neck Cancers, Version 1.2018.Journal of the National Comprehensive Cancer Network.  16:479-490. 2018
2018 Higher carbohydrate intake is associated with increased risk of all-cause and disease-specific mortality in head and neck cancer patients: results from a prospective cohort study.International Journal of Cancer.  143:1105-1113. 2018
2017 NCCN Guidelines Insights: Head and Neck Cancers, Version 2.2017.Journal of the National Comprehensive Cancer Network.  15:761-770. 2017
2016 Cetuximab and Radiotherapy in Laryngeal Preservanion-Reply.JAMA Otolaryngology-Head and Neck Surgery.  143:526. 2016
2016 Long-term results of a phase I/II trial of the addition of celecoxib to chemoradiotherapy for locally advanced or recurrent squamous cell carcinoma of the head-and-neckJournal of Radiation Oncology.  5:363-369. 2016
2016 Establishing quality indicators for neck dissection: Correlating the number of lymph nodes with oncologic outcomes (NRG Oncology RTOG 9501 and RTOG 0234).Cancer.  122:3464-3471. 2016
2016 Smoking Cessation, Version 1.2016, NCCN Clinical Practice Guidelines in Oncology.Journal of the National Comprehensive Cancer Network.  14:1430-1468. 2016
2016 Analysis of Predictive Factors for Acute Esophagitis in Lung Cancer Radiation Therapy.International Journal of Radiation Oncology - Biology - Physics.  96:E193-E194. 2016
2016 Analysis of Predictive Factors for Pneumonitis in Lung Cancer Radiation Therapy.International Journal of Radiation Oncology - Biology - Physics.  96:E482-E483. 2016
2016 Association of human papillomavirus and p16 status with mucositis and dysphagia for head and neck cancer patients treated with radiotherapy with or without cetuximab: Assessment from a phase 3 registration trial.European journal of cancer.  64:1-11. 2016
2016 Cetuximab and Radiotherapy in Laryngeal Preservation for Cancers of the Larynx and Hypopharynx: A Secondary Analysis of a Randomized Clinical Trial.JAMA Otolaryngology-Head and Neck Surgery.  142:842-849. 2016
2016 Correlation Between the Severity of Cetuximab-Induced Skin Rash and Clinical Outcome for Head and Neck Cancer Patients: The RTOG Experience.International Journal of Radiation Oncology - Biology - Physics.  95:1346-1354. 2016
2016 A phase 2 study of radiosurgery and temozolomide for patients with 1 to 4 brain metastases.Advances in Radiation Oncology.  1:83-88. 2016
2015 Evaluation of 3M™ Molecular Detection Assay (MDA) Listeria for the Detection of Listeria species in Selected Foods and Environmental Surfaces: Collaborative Study, First Action 2014.06.Journal of AOAC INTERNATIONAL.  98:993-1002. 2015
2015 Evaluation of 3M™ Molecular Detection Assay (MDA) Listeria monocytogenes for the Detection of Listeria monocytogenes in Selected Foods and Environmental Surfaces: Collaborative Study, First Action 2014.07.Journal of AOAC INTERNATIONAL.  98:980-992. 2015
2015 Head and Neck Cancers, Version 1.2015.Journal of the National Comprehensive Cancer Network.  13:847-855. 2015
2014 Comparison of plan quality and delivery time between volumetric arc therapy (RapidArc) and Gamma Knife radiosurgery for multiple cranial metastases.Neurosurgery.  75:409-417. 2014
2014 Head and neck cancers, Version 2.2014. Clinical practice guidelines in oncology.Journal of the National Comprehensive Cancer Network.  12:1454-1487. 2014
2014 Induction cetuximab, paclitaxel, and carboplatin followed by chemoradiation with cetuximab, paclitaxel, and carboplatin for stage III/IV head and neck squamous cancer: a phase II ECOG-ACRIN trial (E2303).Annals of Oncology.  25:2036-2041. 2014
2014 Pazopanib combined with radiation: in vivo model of interaction.Cancer Biotherapy and Radiopharmaceuticals.  29:247-250. 2014
2014 Final results of local-regional control and late toxicity of RTOG 9003: a randomized trial of altered fractionation radiation for locally advanced head and neck cancer.International Journal of Radiation Oncology - Biology - Physics.  89:13-20. 2014
2014 African Americans with oropharyngeal carcinoma have significantly poorer outcomes despite similar rates of human papillomavirus-mediated carcinogenesis.Human Pathology.  45:310-319. 2014
2014 A technique using 99mTc-mebrofenin SPECT for radiotherapy treatment planning for liver cancers or metastases.Medical Dosimetry.  39:7-11. 2014
2013 Stereotactic body radiation therapy (SBRT) for lung malignancies: preliminary toxicity results using a flattening filter-free linear accelerator operating at 2400 monitor units per minute.Radiation Oncology.  8:273. 2013
2013 Head and neck cancers, version 2.2013. Featured updates to the NCCN guidelines.Journal of the National Comprehensive Cancer Network.  11:917-923. 2013
2013 Flattening filter-free linac improves treatment delivery efficiency in stereotactic body radiation therapy.Journal of Applied Clinical Medical Physics.  14:4126. 2013
2013 Phase 1 study of erlotinib plus radiation therapy in patients with advanced cutaneous squamous cell carcinoma.International Journal of Radiation Oncology - Biology - Physics.  85:1275-1281. 2013
2013 Intraoperative ultrasound guidance during intracavitary brachytherapy applicator placement in cervical cancer: the University of Alabama at Birmingham experience.International Journal of Gynecological Cancer.  23:559-566. 2013
2013 Locoregional failure and the risk of distant metastasis after modern radiotherapy for head and neck cancer.Head & neck surgery.  35:381-387. 2013
2013 Flattening filter-free linac improves treatment delivery efficiency in stereotactic body radiation therapyJournal of Applied Clinical Medical Physics.  14:64-71. 2013
2012 Prognostic significance of thyroid or cricoid cartilage invasion in laryngeal or hypopharyngeal cancer treated with organ preserving strategies.Radiation Oncology.  7:219. 2012
2012 Influenza immunization in older adults with and without cancer.Journal of the American Geriatrics Society.  60:2099-2103. 2012
2012 Plan quality and treatment planning technique for single isocenter cranial radiosurgery with volumetric modulated arc therapy.Practical Radiation Oncology.  2:306-313. 2012
2012 Tobacco smoking and increased risk of death and progression for patients with p16-positive and p16-negative oropharyngeal cancer.Journal of Clinical Oncology.  30:2102-2111. 2012
2012 SU-E-T-434: Use of Deformable Registration for Cumulated Dose Calculation in Image-Guided Intracavitary Bracytherapy for Cervical Cancer.Medical Physics.  39:3804. 2012
2012 Mucosal melanoma of the head and neckJournal of the National Comprehensive Cancer Network.  10:320-338. 2012
2012 Mucosal melanoma: a clinically and biologically unique disease entity.Journal of the National Comprehensive Cancer Network.  10:345-356. 2012
2011 Impact of average weekly dose of radiation during radiotherapy alone or chemoradiotherapy in head and neck cancer.Head & neck surgery.  33:1551-1556. 2011
2011 Examination of laryngoesophageal dysfunction-free survival as an endpoint in nonsurgical treatment of squamous cell carcinomas of the larynx and hypopharynx.Cancer.  117:4447-4451. 2011
2011 Integrating epidermal growth factor receptor assay with clinical parameters improves risk classification for relapse and survival in head-and-neck squamous cell carcinoma.International Journal of Radiation Oncology - Biology - Physics.  81:331-338. 2011
2011 Radiation-induced ocular motor cranial nerve palsies in patients with pituitary tumor.Journal of Neuro-Ophthalmology.  31:210-213. 2011
2011 Head and neck cancers.Journal of the National Comprehensive Cancer Network.  9:596-650. 2011
2011 Glioma-associated oncogene family zinc finger 1 expression and metastasis in patients with head and neck squamous cell carcinoma treated with radiation therapy (RTOG 9003).Journal of Clinical Oncology.  29:1326-1334. 2011
2011 Dosimetric analysis of imaging changes following pulmonary stereotactic body radiation therapy.Australasian Radiology.  55:90-96. 2011
2011 Improved clinical efficiency in CNS stereotactic radiosurgery using a flattening filter free linear accelerator.Journal of Radiosurgery and SBRT.  1:117-122. 2011
2010 Dosimetric factors associated with long-term dysphagia after definitive radiotherapy for squamous cell carcinoma of the head and neck.International Journal of Radiation Oncology - Biology - Physics.  76:403-409. 2010
2010 Effects of bladder distension on organs at risk in 3D image-based planning of intracavitary brachytherapy for cervical cancer.International Journal of Radiation Oncology - Biology - Physics.  76:485-489. 2010
2010 Margin on gross tumor volume and risk of local recurrence in head-and-neck cancer.International Journal of Radiation Oncology - Biology - Physics.  76:164-168. 2010
2010 Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival.Lancet Oncology.  11:21-28. 2010
2009 Postoperative reirradiation for mucosal head and neck squamous cell carcinomas.Archives of Otolaryngology Head and Neck Surgery.  135:1158-1164. 2009
2009 Development of an accelerated GVF semi-automatic contouring algorithm for radiotherapy treatment planning.Computers in Biology and Medicine.  39:650-656. 2009
2009 NCCN Task Force Report: Management of dermatologic and other toxicities associated with EGFR inhibition in patients with cancer.Journal of the National Comprehensive Cancer Network.  7 Suppl 1:S5-21. 2009
2009 Factors associated with long-term dysphagia after definitive radiotherapy for locally advanced head-and-neck cancer.International Journal of Radiation Oncology - Biology - Physics.  73:410-415. 2009
2008 Reirradiation and concurrent chemotherapy after salvage surgery: pay now or pay later.Journal of Clinical Oncology.  26:5500-5501. 2008
2008 Head and neck cancers.Journal of the National Comprehensive Cancer Network.  6:646-695. 2008
2008 Locoregionally advanced head and neck cancer treated with primary radiotherapy: a comparison of the addition of cetuximab or chemotherapy and the impact of protocol treatment.International Journal of Radiation Oncology - Biology - Physics.  71:676-681. 2008
2008 Final report of RTOG 9610, a multi-institutional trial of reirradiation and chemotherapy for unresectable recurrent squamous cell carcinoma of the head and neck.Head & neck surgery.  30:281-288. 2008
2008 Pretreatment quality of life predicts for locoregional control in head and neck cancer patients: a radiation therapy oncology group analysis.International Journal of Radiation Oncology - Biology - Physics.  70:353-360. 2008
2008 Predictors of distant brain recurrence for patients with newly diagnosed brain metastases treated with stereotactic radiosurgery alone.International Journal of Radiation Oncology - Biology - Physics.  70:181-186. 2008
2007 SU‐FF‐J‐78: 3‐D Target Localization at the End of Expiration Prior to Respiration‐Gated Radiotherapy TreatmentMedical Physics.  34:2386. 2007
2007 SU‐FF‐T‐372: Registration of Frameless High‐Field MRI to Low‐Field Frame‐Based MRI Images in Leksell Gamma‐Knife (LGK) RadiosurgeryMedical Physics.  34:2487. 2007
2007 SU‐FF‐T‐426: Treatment Planning Comparison of Dynamic Multileaf Collimation and Helical Tomotherapy for Spinal Cord Sparing in Head and Neck Re‐IrradiationMedical Physics.  34:2499-2500. 2007
2006 Women with pathologic stage I, II, and III non-small cell lung cancer have better survival than men.Chest.  130:1796-1802. 2006
2006 Disadvantage of men living alone participating in Radiation Therapy Oncology Group head and neck trials.Journal of Clinical Oncology.  24:4177-4183. 2006
2006 Postoperative radiotherapy in non-small-cell lung cancer warrants further exploration in the era of adjuvant chemotherapy and conformal radiotherapy.Journal of Clinical Oncology.  24:2978-2980. 2006
2006 An IMRT technique to increase therapeutic ratio of breast irradiation in patients with early stage left breast cancer: Limiting second malignancies.Journal of Clinical Oncology.  24:10791. 2006
2006 The authors and a colleague reply [11]New England Journal of Medicine.  354:2187. 2006
2006 Low-dose-rate vs. high-dose-rate intracavitary brachytherapy for carcinoma of the cervix: The University of Alabama at Birmingham (UAB) experience.Brachytherapy.  5:49-55. 2006
2005 Simultaneous optimization of sequential IMRT plans.Medical Physics.  32:3257-3266. 2005
2005 Pulmonary resection after high-dose and low-dose chest irradiation.Annals of Thoracic Surgery.  80:1224-1230. 2005
2005 Phase I/IIa study of cisplatin and gemcitabine as induction chemotherapy followed by concurrent chemoradiotherapy with gemcitabine and paclitaxel for locally advanced non-small-cell lung cancer.Journal of Clinical Oncology.  23:6664-6673. 2005
2005 Is there disparity in the care of minority patients with upper aerodigestive tract malignancy?Medical Clinics of North America.  89:1033-1041. 2005
2005 Monte Carlo techniques for scattering foil design and dosimetry in total skin electron irradiations.Medical Physics.  32:1460-1468. 2005
2005 Monte Carlo techniques for scattering foil design and dosimetry in total skin electron irradiations.Medical Physics.  32:1460-1468. 2005
2005 Concomitant boost radiation plus concurrent cisplatin for advanced head and neck carcinomas: radiation therapy oncology group phase II trial 99-14.Journal of Clinical Oncology.  23:3008-3015. 2005
2005 Head and neck cancers.Journal of the National Comprehensive Cancer Network.  3:316-391. 2005
2005 SU‐FF‐J‐123: Residual Tumor Motion in Respiratory Gated CT Treatment PlaningMedical Physics.  32:1948. 2005
2005 SU‐FF‐T‐282: Beam Modifier Design for Total Skin Electron Irradiations Using Monte Carlo TechniquesMedical Physics.  32:2015. 2005
2004 A dynamic supraclavicular field-matching technique for head-and-neck cancer patients treated with IMRT.International Journal of Radiation Oncology - Biology - Physics.  60:959-972. 2004
2003 Docetaxel with concurrent radiotherapy in head and neck cancer.Seminars in Oncology.  30:89-93. 2003
2003 Validation of target volume and position in respiratory gated CT planning and treatment.Medical Physics.  30:3196-3205. 2003
2003 Role of radiation therapy and radiosurgery in glioblastoma multiforme.Cancer Journal.  9:222-229. 2003
2003 Phase 1 trial of combined chemotherapy and reirradiation for recurrent unresectable head and neck cancer.Head & neck surgery.  25:118-122. 2003
2002 Concurrent chemoradiation therapy with cisplatin and paclitaxel for locally advanced non-small cell lung cancer: long-term follow-up of a phase I trial.Lung Cancer.  37:189-199. 2002
2001 RTOG 96-10: reirradiation with concurrent hydroxyurea and 5-fluorouracil in patients with squamous cell cancer of the head and neck.International Journal of Radiation Oncology - Biology - Physics.  51:1299-1304. 2001
2001 Phase I study of anti--epidermal growth factor receptor antibody cetuximab in combination with radiation therapy in patients with advanced head and neck cancer.Journal of Clinical Oncology.  19:3234-3243. 2001
2000 Enhanced apoptosis with combination C225/radiation treatment serves as the impetus for clinical investigation in head and neck cancers.Journal of Clinical Oncology.  18:47S-53S. 2000
2000 NCCN Practice Guidelines for Head and Neck Cancers.Oncology.  14:163-194. 2000
2000 Tumor shrinkage before intracavitary brachytherapy for cancer of the cervix: radiotherapy alone versus concurrent chemoradiotherapy.Cancer Journal.  6:377-380. 2000
2000 A Radiation Therapy Oncology Group (RTOG) phase III randomized study to compare hyperfractionation and two variants of accelerated fractionation to standard fractionation radiotherapy for head and neck squamous cell carcinomas: first report of RTOG 9003.International Journal of Radiation Oncology - Biology - Physics.  48:7-16. 2000
2000 A prospective evaluation of the timing of postoperative radiotherapy for preventing heterotopic ossification following traumatic acetabular fractures.International Journal of Radiation Oncology - Biology - Physics.  47:1347-1352. 2000
2000 A phase I study of combined UFT plus leucovorin and radiotherapy for pancreatic cancer.International Journal of Radiation Oncology - Biology - Physics.  47:939-944. 2000
1999 UFT/oral calcium folinate plus radiation in pancreatic cancer.Oncology.  13:127-128. 1999
1999 Chemoradiotherapy of locally advanced esophageal cancer: long-term follow-up of a prospective randomized trial (RTOG 85-01). Radiation Therapy Oncology Group.Journal of the American Medical Association.  281:1623-1627. 1999
1999 Monoclonal antibodies as potentiators of radiotherapy and chemotherapy in the management of head and neck cancer.Current Opinion in Oncology.  11:187-190. 1999
1999 Multimodality therapy of patients with locally advanced squamous cell cancer of the head and neck: preliminary results of two pilot trials using paclitaxel and cisplatin.Seminars in Radiation Oncology.  9:64-69. 1999
1999 Phase I/IIa study of concurrent paclitaxel and cisplatin with radiation therapy in locally advanced non-small cell lung cancer: analysis of early and late pulmonary morbidity.Seminars in Radiation Oncology.  9:136-147. 1999
1999 Concomitant chemotherapy and reirradiation as management for recurrent cancer of the head and neck.American Journal of Clinical Oncology.  22:1-5. 1999
1998 Intratumoral cisplatin/epinephrine-injectable gel as a palliative treatment for accessible solid tumors: a multicenter pilot study.Otolaryngology - Head and Neck Surgery.  118:496-503. 1998
1997 An umbilical metastasis after laparoscopy for squamous cell carcinoma of the cervix.Gynecologic Oncology.  64:507-509. 1997
1997 Sucralfate for radiation mucositis: results of a double-blind randomized trial.International Journal of Radiation Oncology - Biology - Physics.  37:275-279. 1997
1996 Postsurgical recurrent carcinoma of the cervix: reassessment and results of radiation therapy options.Radiology.  201:559-563. 1996
1996 Major geometric variations between intracavitary applications in carcinoma of the cervix: high dose rate vs. low dose rate.International Journal of Radiation Oncology - Biology - Physics.  35:1035-1038. 1996
1995 Initial clinical evaluation of iodine-125-labeled chimeric 17-1A for metastatic colon cancer.Journal of Nuclear Medicine.  36:2229-2233. 1995
1995 Major geometric variations between multiple high-dose-rate applications of brachytherapy in cancer of the cervix: frequency and types of variation.Radiology.  195:419-422. 1995
1995 Cisplatin plus radiation therapy.The Journal of infusional chemotherapy.  5:61-66. 1995
1995 Conventional four-field pelvic radiotherapy technique without computed tomography-treatment planning in cancer of the cervix: potential geographic miss and its impact on pelvic control.International Journal of Radiation Oncology - Biology - Physics.  31:109-112. 1995
1994 A clinically practical electron cone for the treatment of head and neck cancer.International Journal of Radiation Oncology - Biology - Physics.  28:1025-1028. 1994
1994 Conventional four-field pelvic radiotherapy technique without CT treatment planning in cancer of the cervix: potential geographic miss.Radiotherapy and Oncology.  30:140-145. 1994
1993 Malignant epidural spinal cord compression associated with a paravertebral mass: its radiotherapeutic outcome on radiosensitivity.International Journal of Radiation Oncology - Biology - Physics.  27:1079-1083. 1993
1993 The influence of staging laparotomy for cervical cancer on patterns of recurrence and survival.International Journal of Gynecological Cancer.  3:169-174. 1993
1993 The influence of staging laparotomy for on patterns of recurrence and survival cervical cancerInternational Journal of Gynecological Cancer.  3:169-174. 1993
1992 A phase I study of high-dose cisplatin, prolonged infusion 5-fluorouracil, and concomitant conventional fraction radiation therapy in patients with inoperable squamous cell carcinoma of the head and neck.American Journal of Clinical Oncology.  15:461-463. 1992
1992 Treatment of recurrent head and neck cancer with 5-fluorouracil, hydroxyurea, and reirradiation.International Journal of Radiation Oncology - Biology - Physics.  22:1051-1056. 1992
1991 Three-port perineal sparing technique.Radiology.  180:563-566. 1991
1991 Pharmacokinetics, immune response, and biodistribution of iodine-131-labeled chimeric mouse/human IgG1,k 17-1A monoclonal antibody.Journal of Nuclear Medicine.  32:1162-1168. 1991
1991 A phase I study of prolonged infusion 5-fluorouracil and concomitant radiation therapy in patients with squamous cell cancer of the head and neck.International Journal of Radiation Oncology - Biology - Physics.  20:357-360. 1991
1990 Extradural spinal cord compression: analysis of factors determining functional prognosis--prospective study.Radiology.  176:279-282. 1990

Chapter

Year Title Altmetric
2010 Impact of dose rate on outcomes of Gamma Knife® radiosurgery in patients with face pain.  360-365. 2010

Principal Investigator On

Education And Training

  • Doctor of Medicine, University of Alabama at Birmingham
  • Master of Science in Health / Health Care Administration / Management, University of Alabama at Birmingham
  • Full Name

  • Sharon Spencer