Positions

Selected Publications

Academic Article

Year Title Altmetric
2019 Efficacy of Intraoperative Antiseptic Techniques in the Prevention of Periprosthetic Joint Infection: Superiority of BetadineJournal of Arthroplasty.  34:S312-S318. 2019
2019 Pyrazolopyrimidinones, a novel class of copper-dependent bactericidal antibiotics against multi-drug resistant: S. aureusMetallomics.  11:784-798. 2019
2019 High-throughput screening and Bayesian machine learning for copper-dependent inhibitors of: Staphylococcus aureusMetallomics.  11:696-706. 2019
2019 Assaying for inorganic polyphosphate in bacteriaJournal of Visualized Experiments.  2019. 2019
2019 Differential susceptibility of Mycoplasma and Ureaplasma species to compound-enhanced copper toxicityFrontiers in Microbiology.  10. 2019
2017 Mycobacterium tuberculosis exploits the PPM1A signaling pathway to block host macrophage apoptosisScientific Reports.  7. 2017
2017 Copper and Antibiotics: Discovery, Modes of Action, and Opportunities for Medicinal ApplicationsAdvances in Microbial Physiology.  70:193-260. 2017
2016 8-Hydroxyquinolines are boosting agents of copper-related toxicity in Mycobacterium tuberculosisAntimicrobial Agents and Chemotherapy.  60:5765-5776. 2016
2016 A Macrophage Infection Model to Predict Drug Efficacy Against Mycobacterium TuberculosisASSAY and Drug Development Technologies.  14:345-354. 2016
2016 Development of a web-based tool for automated processing and cataloging of a unique combinatorial drug screenJournal of Microbiological Methods.  126:30-34. 2016
2016 Targeting biofilm associated Staphylococcus aureus using resazurin based drug-susceptibility assayJournal of Visualized Experiments.  2016. 2016
2016 Combinatorial phenotypic screen uncovers unrecognized family of extended thiourea inhibitors with copper-dependent anti-staphylococcal activityMetallomics.  8:412-421. 2016
2016 Protein phosphatase, Mg2+/Mn2+-dependent 1A controls the innate antiviral and antibacterial response of macrophages during HIV-1 and Mycobacterium tuberculosis infectionOncotarget.  7:15394-15409. 2016
2015 RNAP II processivity is a limiting step for HIV-1 transcription independent of orientation to and activity of endogenous neighboring promotersVirology.  486:7-14. 2015
2015 Disulfiram and copper ions kill Mycobacterium tuberculosis in a synergistic mannerAntimicrobial Agents and Chemotherapy.  59:4835-4844. 2015
2015 Mycobacteria, metals, and the macrophageImmunological Reviews.  264:249-263. 2015
2015 Stable phenotypic changes of the host T cells are essential to the long-term stability of latent HIV-1 infectionJournal of Virology.  89:6656-6672. 2015
2014 Copper complexation screen reveals compounds with potent antibiotic properties against methicillin-resistant Staphylococcus aureusAntimicrobial Agents and Chemotherapy.  58:3727-3736. 2014
2014 Kinase control of latent HIV-1 infection: PIM-1 kinase as a major contributor to HIV-1 reactivationJournal of Virology.  88:364-376. 2014
2013 Porins increase copper susceptibility of Mycobacterium tuberculosisJournal of Bacteriology.  195:5133-5140. 2013
2013 An AP-1 binding site in the enhancer/core element of the HIV-1 promoter controls the ability of HIV-1 to establish latent infectionJournal of Virology.  87:2264-2277. 2013
2013 Copper-boosting compounds: A novel concept for antimycobacterial drug discoveryAntimicrobial Agents and Chemotherapy.  57:1089-1091. 2013
2012 Selected drugs with reported secondary cell-differentiating capacity prime latent HIV-1 infection for reactivationJournal of Virology.  86:9055-9069. 2012
2012 Kinase control prevents HIV-1 reactivation in spite of high levels of induced NF-κB activityJournal of Virology.  86:4548-4558. 2012
2011 Facts and fiction: Cellular models for high throughput screening for HIV-1 reactivating drugsCurrent HIV Research.  9:568-578. 2011
2011 Copper resistance is essential for virulence of Mycobacterium tuberculosisProceedings of the National Academy of Sciences.  108:1621-1626. 2011
2010 Hit-and-run stimulation: A novel concept to reactivate latent HIV-1 infection without cytokine gene inductionJournal of Virology.  84:8712-8720. 2010
2009 Construction of unmarked deletion mutants in mycobacteria.Methods in Molecular Biology.  465:279-295. 2009
2008 Rv1698 of Mycobacterium tuberculosis represents a new class of channel-forming outer membrane proteinsJournal of Biological Chemistry.  283:17827-17837. 2008
2008 Construction of unmarked deletion mutants in mycobacteriaMethods in Molecular Biology.  465:279-295. 2008
2007 Identification of two Mycobacterium smegmatis lipoproteins exported by a SecA2-dependent pathwayJournal of Bacteriology.  189:5090-5100. 2007
2007 Porins are required for uptake of phosphates by Mycobacterium smegmatisJournal of Bacteriology.  189:2435-2442. 2007
2005 The growth rate of Mycobacterium smegmatis depends on sufficient porin-mediated influx of nutrientsMicrobiological sciences.  58:714-730. 2005
2005 4-Dihydromethyltrisporate dehydrogenase, an enzyme of the sex hormone pathway in Mucor mucedo, is constitutively transcribed but its activity is differently regulated in (+) and (-) mating typesExperimental mycology.  42:804-812. 2005

Education And Training

  • Doctor of Philosophy Level Degree in Natural Sciences, Friedrich-Alexander University of Erlangen-Nuremberg 2008
  • Bachelor's Level Degree in Biology, Friedrich Schiller University Jena 2002
  • Full Name

  • Frank Wolschendorf