Positions

Selected Publications

Academic Article

Year Title Altmetric
2019 Efficacy of Intraoperative Antiseptic Techniques in the Prevention of Periprosthetic Joint Infection: Superiority of BetadineJournal of Arthroplasty.  34:S312-S318. 2019
2019 Pyrazolopyrimidinones, a novel class of copper-dependent bactericidal antibiotics against multi-drug resistant: S. aureusMetallomics.  11:784-798. 2019
2019 High-throughput screening and Bayesian machine learning for copper-dependent inhibitors of: Staphylococcus aureusMetallomics.  11:696-706. 2019
2019 Assaying for inorganic polyphosphate in bacteriaJournal of Visualized Experiments.  2019. 2019
2017 Mycobacterium tuberculosis exploits the PPM1A signaling pathway to block host macrophage apoptosisScientific Reports.  7. 2017
2017 Copper and Antibiotics: Discovery, Modes of Action, and Opportunities for Medicinal ApplicationsAdvances in Microbial Physiology.  70:193-260. 2017
2016 8-Hydroxyquinolines are boosting agents of copper-related toxicity in Mycobacterium tuberculosisAntimicrobial Agents and Chemotherapy.  60:5765-5776. 2016
2016 A Macrophage Infection Model to Predict Drug Efficacy Against Mycobacterium TuberculosisASSAY and Drug Development Technologies.  14:345-354. 2016
2016 Development of a web-based tool for automated processing and cataloging of a unique combinatorial drug screenJournal of Microbiological Methods.  126:30-34. 2016
2016 Targeting biofilm associated Staphylococcus aureus using resazurin based drug-susceptibility assayJournal of Visualized Experiments.  2016. 2016
2016 Combinatorial phenotypic screen uncovers unrecognized family of extended thiourea inhibitors with copper-dependent anti-staphylococcal activityMetallomics.  8:412-421. 2016
2016 Protein phosphatase, Mg2+/Mn2+-dependent 1A controls the innate antiviral and antibacterial response of macrophages during HIV-1 and Mycobacterium tuberculosis infectionOncotarget.  7:15394-15409. 2016
2015 RNAP II processivity is a limiting step for HIV-1 transcription independent of orientation to and activity of endogenous neighboring promotersVirology.  486:7-14. 2015
2015 Disulfiram and copper ions kill Mycobacterium tuberculosis in a synergistic mannerAntimicrobial Agents and Chemotherapy.  59:4835-4844. 2015
2015 Mycobacteria, metals, and the macrophageImmunological Reviews.  264:249-263. 2015
2015 Stable phenotypic changes of the host T cells are essential to the long-term stability of latent HIV-1 infectionJournal of Virology.  89:6656-6672. 2015
2015 The role of porins in copper acquisition by mycobacteriaInternational Journal of Mycobacteriology2015
2014 Copper complexation screen reveals compounds with potent antibiotic properties against methicillin-resistant Staphylococcus aureusAntimicrobial Agents and Chemotherapy.  58:3727-3736. 2014
2014 Kinase control of latent HIV-1 infection: PIM-1 kinase as a major contributor to HIV-1 reactivationJournal of Virology.  88:364-376. 2014
2013 Porins increase copper susceptibility of Mycobacterium tuberculosisJournal of Bacteriology.  195:5133-5140. 2013
2013 An AP-1 binding site in the enhancer/core element of the HIV-1 promoter controls the ability of HIV-1 to establish latent infectionJournal of Virology.  87:2264-2277. 2013
2013 Copper-boosting compounds: A novel concept for antimycobacterial drug discoveryAntimicrobial Agents and Chemotherapy.  57:1089-1091. 2013
2012 Selected drugs with reported secondary cell-differentiating capacity prime latent HIV-1 infection for reactivationJournal of Virology.  86:9055-9069. 2012
2012 Kinase control prevents HIV-1 reactivation in spite of high levels of induced NF-κB activityJournal of Virology.  86:4548-4558. 2012
2011 Facts and fiction: Cellular models for high throughput screening for HIV-1 reactivating drugsCurrent HIV Research.  9:568-578. 2011
2011 Copper resistance is essential for virulence of Mycobacterium tuberculosisProceedings of the National Academy of Sciences.  108:1621-1626. 2011
2010 Hit-and-run stimulation: A novel concept to reactivate latent HIV-1 infection without cytokine gene inductionJournal of Virology.  84:8712-8720. 2010
2009 Construction of unmarked deletion mutants in mycobacteria.Methods in Molecular Biology.  465:279-295. 2009
2008 Rv1698 of Mycobacterium tuberculosis represents a new class of channel-forming outer membrane proteinsJournal of Biological Chemistry.  283:17827-17837. 2008
2008 Construction of unmarked deletion mutants in mycobacteriaMethods in Molecular Biology.  465:279-295. 2008
2007 Identification of two Mycobacterium smegmatis lipoproteins exported by a SecA2-dependent pathwayJournal of Bacteriology.  189:5090-5100. 2007
2007 Porins are required for uptake of phosphates by Mycobacterium smegmatisJournal of Bacteriology.  189:2435-2442. 2007
2005 The growth rate of Mycobacterium smegmatis depends on sufficient porin-mediated influx of nutrientsMicrobiological sciences.  58:714-730. 2005
2005 4-Dihydromethyltrisporate dehydrogenase, an enzyme of the sex hormone pathway in Mucor mucedo, is constitutively transcribed but its activity is differently regulated in (+) and (-) mating typesExperimental mycology.  42:804-812. 2005

Education And Training

  • Doctor of Philosophy Level Degree in Natural Sciences, Friedrich-Alexander University of Erlangen-Nuremberg 2008
  • Bachelor's Level Degree in Biology, Friedrich Schiller University Jena 2002
  • Full Name

  • Frank Wolschendorf