Positions

Selected Publications

Academic Article

Year Title Altmetric
2019 Pyrazolopyrimidinones, a novel class of copper-dependent bactericidal antibiotics against multi-drug resistant S. aureus. 2019
2019 High-throughput screening and Bayesian machine learning for copper-dependent inhibitors of: Staphylococcus aureus 2019
2019 Assaying for inorganic polyphosphate in bacteria 2019
2019 Efficacy of Intraoperative Antiseptic Techniques in the Prevention of Periprosthetic Joint Infection: Superiority of Betadine 2019
2017 Mycobacterium tuberculosis exploits the PPM1A signaling pathway to block host macrophage apoptosis 2017
2017 Copper and Antibiotics: Discovery, Modes of Action, and Opportunities for Medicinal Applications 2017
2016 8-Hydroxyquinolines are boosting agents of copper-related toxicity in Mycobacterium tuberculosis 2016
2016 A Macrophage Infection Model to Predict Drug Efficacy Against Mycobacterium Tuberculosis 2016
2016 Development of a web-based tool for automated processing and cataloging of a unique combinatorial drug screen 2016
2016 Targeting biofilm associated Staphylococcus aureus using resazurin based drug-susceptibility assay 2016
2016 Combinatorial phenotypic screen uncovers unrecognized family of extended thiourea inhibitors with copper-dependent anti-staphylococcal activity 2016
2016 Protein phosphatase, Mg2+/Mn2+-dependent 1A controls the innate antiviral and antibacterial response of macrophages during HIV-1 and Mycobacterium tuberculosis infection 2016
2015 RNAP II processivity is a limiting step for HIV-1 transcription independent of orientation to and activity of endogenous neighboring promoters 2015
2015 Disulfiram and copper ions kill Mycobacterium tuberculosis in a synergistic manner 2015
2015 Mycobacteria, metals, and the macrophage 2015
2015 Stable phenotypic changes of the host T cells are essential to the long-term stability of latent HIV-1 infection 2015
2014 Copper complexation screen reveals compounds with potent antibiotic properties against methicillin-resistant Staphylococcus aureus 2014
2014 Kinase control of latent HIV-1 infection: PIM-1 kinase as a major contributor to HIV-1 reactivation 2014
2013 Porins increase copper susceptibility of Mycobacterium tuberculosis 2013
2013 An AP-1 binding site in the enhancer/core element of the HIV-1 promoter controls the ability of HIV-1 to establish latent infection 2013
2013 Copper-boosting compounds: A novel concept for antimycobacterial drug discovery 2013
2012 Selected drugs with reported secondary cell-differentiating capacity prime latent HIV-1 infection for reactivation 2012
2012 Kinase control prevents HIV-1 reactivation in spite of high levels of induced NF-κB activity 2012
2011 Facts and fiction: Cellular models for high throughput screening for HIV-1 reactivating drugs 2011
2011 Copper resistance is essential for virulence of Mycobacterium tuberculosis 2011
2010 Hit-and-run stimulation: A novel concept to reactivate latent HIV-1 infection without cytokine gene induction 2010
2008 Rv1698 of Mycobacterium tuberculosis represents a new class of channel-forming outer membrane proteins 2008
2007 Identification of two Mycobacterium smegmatis lipoproteins exported by a SecA2-dependent pathway 2007
2007 Porins are required for uptake of phosphates by Mycobacterium smegmatis 2007
2005 The growth rate of Mycobacterium smegmatis depends on sufficient porin-mediated influx of nutrients 2005
2005 4-Dihydromethyltrisporate dehydrogenase, an enzyme of the sex hormone pathway in Mucor mucedo, is constitutively transcribed but its activity is differently regulated in (+) and (-) mating types 2005

Education And Training

  • Doctor of Philosophy Level Degree in Natural Sciences, Friedrich-Alexander University of Erlangen-Nuremberg 2008
  • Bachelor's Level Degree in Biology, Friedrich Schiller University Jena 2002
  • Full Name

  • Frank Wolschendorf