Positions

Overview

  • The general focus and goal of Dr. Cook's research is the application of psychophysiological methods to improve understanding of psychological and biological factors related to emotion, personality, and mental disorders. Current research uses in the startle response as a tool for exploring changes in emotional and sensory information processing that occur with changes in anxiety and mood. Startle is readily measured from humans in the laboratory, typically as contractions of the muscles surrounding the eye in response to an abrupt noise or airpuff.

    Although startle is a relatively fast and simple reflexive response, its magnitude (roughly equivalent to force or vigor) is altered by emotional state. Thus, startle responses are larger during unpleasant emotional states and smaller during pleasant emotional states. Research conducted in Dr. Cook's laboratory indicates that the degree to which these changes occur varies with personality characteristics (such as fearfulness and tendencies toward dissociative or schizotypal thinking). Complementary findings from other laboratories indicate similar differences among anxiety disordered groups and among psychopaths. Because the neural basis of startle modulation is well-researched in animals, startle modulation abnormalities in humans can be used to suggest neural mechanisms and abnormalities that lead to or are associated with personality problems and mental illnesses. A current project examines this hypothesis using functional neuroimaging.

    Dr. Cook's research has primarily been funded by the National Institute of Mental Health, with smaller grants coming from the National Institute on Aging and the National Institute of Dental Research, as well as the Graduate School and the Center for Neuroimaging Research at UAB.

    Dr. Cook is a licensed clinical psychologist who maintains a small private practice, primarily providing treatment for anxiety and depressive disorders.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2015 Emotional and Physiological Desensitization to Real-Life and Movie ViolenceJournal of Youth and Adolescence.  44:1092-1108. 2015
    2014 Emotional and Physiological Desensitization to Real-Life and Movie ViolenceJournal of Youth and Adolescence2014
    2013 Greater impulsivity is associated with decreased brain activation in obese women during a delay discounting taskBrain Imaging and Behavior.  7:116-128. 2013
    2012 FMRI reactivity on a delay discounting task predicts weight gain in obese womenAppetite.  58:582-592. 2012
    2012 FMRI reactivity to high-calorie food pictures predicts short- and long-term outcome in a weight-loss programNeuroImage.  59:2709-2721. 2012
    2009 Effective connectivity of a reward network in obese womenBrain Research Bulletin.  79:388-395. 2009
    2009 A Method for Standardizing Procedures in Rehabilitation: Use in the Extremity Constraint Induced Therapy Evaluation Multisite Randomized Controlled TrialArchives of Physical Medicine and Rehabilitation.  90:663-668. 2009
    2008 Obese women show greater delay discounting than healthy-weight womenAppetite.  51:563-569. 2008
    2008 Widespread reward-system activation in obese women in response to pictures of high-calorie foodsNeuroImage.  41:636-647. 2008
    2007 Anxiety and defensiveness: Individual differences in affective startle modulationMotivation and Emotion.  31:115-123. 2007
    2007 Motivational state modulates the hedonic value of food images differently in men and womenAppetite.  48:139-144. 2007
    2001 Anxiety and defensiveness: Individual differences in valence modulation of startlePsychophysiology.  38:S16-S17. 2001
    2001 The reliability of the wolf motor function test for assessing upper extremity function after strokeArchives of Physical Medicine and Rehabilitation.  82:750-755. 2001
    2000 Independence of valence modulation and prepulse inhibition of startlePsychophysiology.  37:5-12. 2000
    1999 Startle modulation, temperamental fear, and clinical anxiety: An updatePsychophysiology.  36:S4-S4. 1999
    1999 Valence, arousal, and startle reflex modulation in subjects reporting PTSD symptomsPsychophysiology.  36:S113-S113. 1999
    1998 Digital filtering in EEG/ERP analysis: Some technical and empirical comparisonsBehavior Research Methods Instruments and Computers.  30:54-67. 1998
    1997 Affective modulation of tactile startlePsychophysiology.  34:23-31. 1997
    1997 Anxiety in adult fixed-wing air transport patientsAir Medical Journal.  16:77-80. 1997
    1997 Relationships between startle and cardiovascular reactivityPsychophysiology.  34:87-96. 1997
    1996 The structure of emotion: Psychophysiological, cognitive and clinical aspects - Birbaumer,N, Ohman,ABiofeedback and self-regulation.  21:291-295. 1996
    1996 Specificity of startle modulation revisited: Relationships of affective and prepulse modification to fearfulness and schizotypyPsychophysiology.  33:S31-S31. 1996
    1996 Factor analysis of gastrointestinal symptoms [5]Gastroenterology.  110:969-970. 1996
    1996 Impact of irritable bowel syndrome on quality of lifeDigestive Diseases and Sciences.  41:2248-2253. 1996
    1995 Irritable bowel syndrome defined by factor analysis gender and race comparisonsDigestive Diseases and Sciences.  40:2647-2655. 1995
    1995 AFFECTIVE MODULATION OF STARTLE IN CHILDRENPsychophysiology.  32:S25-S25. 1995
    1995 APPLICATIONS OF DIGITAL FILTERING TO STARTLE BLINK MEASUREMENTPsychophysiology.  32:S13-S13. 1995
    1995 RELATIONSHIPS BETWEEN VALENCE MODULATION AND PREPULSE INHIBITION OF STARTLEPsychophysiology.  32:S39-S39. 1995
    1995 SPONTANEOUS EYEBLINK - ELECTROMYOGRAPHIC MEASUREMENT AND AFFECTIVE MODULATIONPsychophysiology.  32:S58-S58. 1995
    1995 STARTLE BLINK MEASUREMENT - STIMULUS, RESPONSE, AND QUANTIFICATION ISSUESPsychophysiology.  32:S12-S12. 1995
    1995 Coping with irritable bowel syndrome IBS): Analgesic and other medication use by IBS patients and IBS non-consulterGastroenterology.  108:A577-A577. 1995
    1995 Spontaneous swallowing rate and emotional state - Possible mechanism for stress-related gastrointestinal disordersDigestive Diseases and Sciences.  40:282-286. 1995
    1994 AN OPERANT APPROACH TO REHABILITATION MEDICINE: OVERCOMING LEARNED NONUSE BY SHAPINGJournal of the Experimental Analysis of Behavior.  61:281-293. 1994
    1993 Behavioral assessments of two drug combinations for oral sedation.Pediatric Dentistry.  15:186-190. 1993
    1993 EMOTIONAL DISTRESS, RELAXATION AND AIR SWALLOWING RATE - A POSSIBLE ETIOLOGIC MECHANISM IN SOME GASTROINTESTINAL DISORDERSGastroenterology.  104:A1035-A1035. 1993
    1993 FACTOR-ANALYSIS OF BOWEL SYMPTOMS - REPLICATION IN 2045 STUDENTSGastroenterology.  104:A492-A492. 1993
    1993 Technique to improve chronic motor deficit after strokeArchives of Physical Medicine and Rehabilitation.  74:347-354. 1993
    1992 The effects of eyelid closure on affective imagery and eyeblink startleJournal of Psychophysiology.  6:299-310. 1992
    1992 Digital Filtering: Background and Tutorial for PsychophysiologistsPsychophysiology.  29:350-362. 1992
    1992 Fearfulness and Startle Potentiation during Aversive Visual StimuliPsychophysiology.  29:633-645. 1992
    1992 The effects of aerobic exercise on cardiovascular, facial EMG, and self- report responses to emotional imageryPsychosomatic Medicine.  54:109-120. 1992
    1991 Affective individual differences and startle reflex modulation.Journal of Abnormal Psychology.  100:5-13. 1991
    1991 Affective Individual Differences and Startle Reflex ModulationJournal of Abnormal Psychology.  100:5-13. 1991
    1990 Dentists' voice control: effects on children's disruptive and affective behavior.Health Psychology.  9:546-558. 1990
    1989 Affective judgment and psychophysiological response: Dimensional covariation in the evaluation of pictorial stimuliJournal of Psychophysiology.  3:51-64. 1989
    1989 Emotional imagery and the defferential diagnosis of anxietyInternational Journal of Psychophysiology.  7:311-312. 1989
    1988 Sequential patterns of medical stress: Maternal agitation and child distressChild and Family Behavior Therapy.  10:9-18. 1988
    1988 Emotional Imagery and the Differential Diagnosis of AnxietyJournal of Consulting and Clinical Psychology.  56:734-740. 1988
    1988 Slow Brain Potentials, Imagery And Hemispheric DifferencesInternational Journal of Neuroscience.  39:101-116. 1988
    1986 Preparedness and Phobia. Effects of Stimulus Content on Human Visceral ConditioningJournal of Abnormal Psychology.  95:195-207. 1986
    1985 The pain behavior scale: Modification and validation for outpatient useJournal of Psychopathology and Behavioral Assessment.  7:301-315. 1985
    1985 Individual Differences in Autonomic Response: Conditioned Association or Conditioned Fear?Psychophysiology.  22:545-560. 1985

    Research Overview

  • Psychopathology, statistics, and emotion
  • Education And Training

  • Doctor of Philosophy in Psychology, University of Wisconsin System : Madison 1983
  • Master of Social or Behavioral Sciences in Psychology, University of Wisconsin System : Madison 1981
  • Full Name

  • Edwin Cook