Positions

Overview

  • Dr. Eckhoff received his undergraduate degree at the University of Michigan in Ann Arbor and his medical diploma from the University of Minnesota. At the University of Wisconsin, he completed a general surgery residency, followed by a transplantation fellowship from 1986-1994. He joined the faculty at the University of Alabama at Birmingham in 1994. In May 2003, he was appointed director of the Division of Transplantation at UAB and in 2004 he became a full professor. Dr. Eckhoff is a member of twenty professional societies including Fellow of American College of Surgeons, American Society of Transplant Surgeons, American Surgical Association and Southern Surgical Association. Dr. Eckhoff serves on a number of councils and committees both for the professional societies as well as internally at UAB. In addition to his title of professor and director of the Division of Transplantation, he has various academic appointments, including medical director of the Alabama Organ Center (AOC), co-director of the UAB Comprehensive Transplant Institute, Arnold G. Diethelm Endowed Chair in Transplantation Surgery and the medical director of transplantation. Dr. Eckhoff is principal investigator on two research projects. He runs an active laboratory in xenotransplant with the desire to transplant genetically modified kidneys from pig models to humans in the near future. Under the progressive direction of Dr. Eckhoff, the transplant program has had significant growth with paired kidney exchange, living related liver donor transplant and various aggressive surgical techniques for tumors including ablation and tumor removal. He has authored, co-authored and collaborated on 132 published manuscripts.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2018 Effect of Renal Diagnosis on Survival in Simultaneous Liver-Kidney Transplantation.Journal of The American College of Surgeons2018
    2018 What's hot, what's new: Report from the American Transplant Congress 2018.American Journal of Transplantation.  18:2857-2868. 2018
    2018 Data on B cell phenotypes in baboons with pig artery patch grafts receiving conventional immunosuppressive therapy.Data in Brief.  20:1965-1974. 2018
    2018 Xenoantigen Deletion and Chemical Immunosuppression Can Prolong Renal Xenograft Survival.Annals of Surgery.  268:564-573. 2018
    2018 Two Cases and a Review of Graft-Versus-Host Disease and the Role of Hepatitis C Treatment in Liver Transplant Patients.Journal of Transplant Coordination.  28:267-270. 2018
    2018 Examining the Biosynthesis and Xenoantigenicity of Class II Swine Leukocyte Antigen Proteins.Journal of Immunology.  200:2957-2964. 2018
    2018 Xenotransplantation-the current status and prospects.British Medical Bulletin.  125:5-14. 2018
    2017 Orthotopic liver transplantation changes the course of gastric antral vascular ectasia: a case series from a transplant center.European Journal of Gastroenterology and Hepatology.  29:973-976. 2017
    2017 Current guidelines for chemoembolization for hepatocellular carcinoma: Room for improvement?Hepatology Communications.  1:338-346. 2017
    2017 A SEER Database Analysis of the Survival Advantage of Transarterial Chemoembolization for Hepatocellular Carcinoma: An Underutilized Therapy.JVIR: Journal of Vascular and Interventional Radiology.  28:231-237.e2. 2017
    2017 Current guidelines for chemoembolization for hepatocellular carcinoma. Room for improvement?Hepatology Communications.  1:338-346. 2017
    2016 Insurance Type and Solid Organ Transplantation Outcomes: A Historical Perspective on How Medicaid Expansion Might Impact Transplantation Outcomes.Journal of The American College of Surgeons.  223:611-620.e4. 2016
    2016 Does the Degree of Hepatocellular Carcinoma Tumor Necrosis following Transarterial Chemoembolization Impact Patient Survival?Journal of Oncology.  2016:4692139. 2016
    2015 Adjuvant stereotactic body radiotherapy following transarterial chemoembolization in patients with non-resectable hepatocellular carcinoma tumours of ‚Č• 3 cm.HPB.  17:140-149. 2015
    2015 The impact of proposed changes in liver allocation policy on cold ischemia times and organ transportation costs.American Journal of Transplantation.  15:541-546. 2015
    2015 Resolution of post-liver transplant anastomotic biliary stricture with successful placement of a self-expanding metallic stent in a child.Endoscopy.  47 Suppl 1 UCTN:E444-E445. 2015
    2014 Predictors of repeat transarterial chemoembolization in the treatment of hepatocellular carcinoma.HPB.  16:1095-1101. 2014
    2014 Hemorrhagic shock one month following uncomplicated liver transplantation.American Journal of Transplantation.  14:1461-1463. 2014
    2014 Transmission of Balamuthia mandrillaris through solid organ transplantation: utility of organ recipient serology to guide clinical management.American Journal of Transplantation.  14:1417-1424. 2014
    2014 Conversion from twice daily tacrolimus capsules to once daily extended-release tacrolimus (LCP-Tacro): phase 2 trial of stable liver transplant recipients.Liver Transplantation and Surgery.  20:564-575. 2014
    2014 Computed tomography predictors of hepatocellular carcinoma tumour necrosis after chemoembolization.HPB.  16:327-335. 2014
    2014 Risk Factors Associated with Reoperation for Bleeding following Liver Transplantation.HPB Surgery.  2014:816246. 2014
    2014 Safety and yield of diagnostic ERCP in liver transplant patients with abnormal liver function tests.Diagnostic and Therapeutic Endoscopy.  2014:314927. 2014
    2013 Do trained specialists solicit familial authorization at equal frequency, regardless of deceased donor characteristics?Journal of Transplant Coordination.  23:290-296. 2013
    2013 Percutaneous balloon dilation and placement of endoscopic biliary stent by using the double-balloon enteroscopy ERCP rendezvous¬†technique.Gastrointestinal Endoscopy.  78:383-385. 2013
    2013 What liver transplant outcomes can be expected in the uninsured who become insured via the Affordable Care Act?American Journal of Transplantation.  13:1533-1540. 2013
    2012 Equivalent survival following liver transplantation in patients with non-alcoholic steatohepatitis compared with patients with other liver diseases.HPB.  14:625-634. 2012
    2012 Sodium nitrite protects against kidney injury induced by brain death and improves post-transplant function.Kidney International.  82:304-313. 2012
    2011 A randomized, multicenter study comparing steroid-free immunosuppression and standard immunosuppression for liver transplant recipients with chronic hepatitis C.Liver Transplantation and Surgery.  17:1394-1403. 2011
    2011 DiscussionJournal of The American College of Surgeons.  212:451-453. 2011
    2010 Inflammation anergy in human intestinal macrophages is due to Smad-induced IkappaBalpha expression and NF-kappaB inactivation.Journal of Biological Chemistry.  285:19593-19604. 2010
    2008 Risk factors and impact of chronic obstructive pulmonary disease in candidates for liver transplantation.Liver Transplantation and Surgery.  14:1357-1365. 2008
    2008 Radiofrequency ablation for unresectable tumors of the liver.American Surgeon.  74:594-600. 2008
    2007 Corticosteroid-free immunosuppression with daclizumab in HCV(+) liver transplant recipients: 1-year interim results of the HCV-3 study.Liver Transplantation and Surgery.  13:1521-1531. 2007
    2007 Inhaled NO accelerates restoration of liver function in adults following orthotopic liver transplantation.Journal of Clinical Investigation.  117:2583-2591. 2007
    2007 Racial disparities in renal allograft survival: a public health issue?Journal of The American College of Surgeons.  204:894-902. 2007
    2007 Combining high selectivity of replication via CXCR4 promoter with fiber chimerism for effective adenoviral oncolysis in breast cancer.International Journal of Cancer.  120:935-941. 2007
    2006 Cytomegalovirus blocks intestinal stroma-induced down-regulation of macrophage HIV-1 infection.Journal of Leukocyte Biology.  80:1111-1117. 2006
    2006 Mucosal IL-8 and TGF-beta recruit blood monocytes: evidence for cross-talk between the lamina propria stroma and myeloid cells.Journal of Leukocyte Biology.  80:492-499. 2006
    2006 Brief communication: Glomerulonephritis in patients with hepatitis C cirrhosis undergoing liver transplantation.Annals of Internal Medicine.  144:735-741. 2006
    2005 Cytoprotection of PEG-modified adult porcine pancreatic islets for improved xenotransplantation.Biomaterials.  26:403-412. 2005
    2004 Current Opinion in Organ Transplantation: Editorial introductionsCurrent Opinion in Organ Transplantation.  9. 2004
    2004 Activated protein C preserves functional islet mass after intraportal transplantation: a novel link between endothelial cell activation, thrombosis, inflammation, and islet cell death.Diabetes.  53:2804-2814. 2004
    2004 Beyond MELD: Toward an outcome-based liver allocation policy?Current Opinion in Organ Transplantation.  9:87-89. 2004
    2004 Nonhuman primate models in type 1 diabetes research.ILAR news.  45:334-342. 2004
    2004 Whither living donors?American Journal of Transplantation.  4:2-3. 2004
    2003 Brain death significantly reduces isolated pancreatic islet yields and functionality in vitro and in vivo after transplantation in rats.Diabetes.  52:2935-2942. 2003
    2003 Radio-frequency ablation in cirrhotic patients with hepatocellular carcinoma.American Surgeon.  69:1067-1071. 2003
    2003 Stable alpha- and beta-islet cell function after tolerance induction to pancreatic islet allografts in diabetic primates.American Journal of Transplantation.  3:128-138. 2003
    2003 New immunosuppressive strategies in liver transplantation: Balancing efficacy and toxicityCurrent Opinion in Organ Transplantation.  8:139-145. 2003
    2002 STEALTH on the preclinical path to toleranceGraft.  5:322-330. 2002
    2002 Use of preserved vascular homografts in liver transplantation: hepatic artery aneurysms and other complications.American Journal of Transplantation.  2:471-475. 2002
    2002 Genetically modified adenovirus vector containing an RGD peptide in the HI loop of the fiber knob improves gene transfer to nonhuman primate isolated pancreatic islets.American Journal of Transplantation.  2:237-243. 2002
    2002 Cytoprotection of pancreatic islets before and early after transplantation using gene therapy.Kidney International.  61:S79-S84. 2002
    2002 Islet transplantation in the twenty-first century.Immunologic Research.  26:289-296. 2002
    2001 Multimodality treatment for patients with hepatocellular carcinoma: analysis of prognostic factors in a single Western institution series.Journal of Gastrointestinal Surgery.  5:638-645. 2001
    2001 Successful reversal of streptozotocin-induced diabetes with stable allogeneic islet function in a preclinical model of type 1 diabetes.Diabetes.  50:1227-1236. 2001
    2001 Combined cardiac surgery and liver transplantation.Liver Transplantation and Surgery.  7:60-61. 2001
    2000 Improved outcomes in cadaveric renal allografts with pulsatile preservation.Clinical Transplantation.  14:543-549. 2000
    2000 Experience with renal transplantation in the nonhuman primate: a modified ureteroneocystostomy to prevent urologic complications.Journal of Investigative Surgery.  13:247-251. 2000
    2000 Biliary cast syndrome: successful endoscopic treatment.Gastrointestinal Endoscopy.  52:78-79. 2000
    2000 Laparoscopic lymphocelectomy: a multi-institutional analysis.Journal of Urology, The.  163:1096-1098. 2000
    2000 Cholecystitis caused by hemocholecyst from underlying malignancy.American Journal of Gastroenterology.  95:805-808. 2000
    2000 Role of ERCP in asymptomatic orthotopic liver transplant patients with abnormal liver enzymesAmerican Journal of Gastroenterology.  95:141-144. 2000
    2000 Role of ERCP in asymptomatic orthotopic liver transplant patients with abnormal liver enzymes.American Journal of Gastroenterology.  95:141-144. 2000
    1999 Reduction of ischemia-reperfusion injury of the liver by in vivo adenovirus-mediated gene transfer of the antiapoptotic Bcl-2 gene.Annals of Surgery.  230:185-193. 1999
    1998 Race: a critical factor in organ donation, patient referral and selection, and orthotopic liver transplantation?Liver Transplantation and Surgery.  4:499-505. 1998
    1998 Conjugated estrogen reduces transfusion and coagulation factor requirements in orthotopic liver transplantation.Anesthesia and Analgesia.  86:1183-1186. 1998
    1997 Adenoviral vector infection of the human exocrine pancreas.Archives of Surgery -New York-.  132:1006-1009. 1997
    1996 Immunohistochemical evaluations of ultrashort-segment Hirschsprung's disease. Report of three cases.Diseases of the Colon and Rectum.  39:817-822. 1996
    1994 100 consecutive liver transplants in infants and children: an 8-year experience.Journal of Pediatric Surgery.  29:1135-1139. 1994
    1994 Proctocolectomy and quadruple-limb W pouch reconstruction for the management of pediatric ulcerative colitis and familial polyposis.Journal of Pediatric Surgery.  29:504-509. 1994
    1993 Urological complications in 210 consecutive simultaneous pancreas-kidney transplants with bladder drainage.Annals of Surgery.  218:561-568. 1993
    1993 Surgical complications after simultaneous pancreas-kidney transplant with bladder drainage.Clinical Transplants.  185-191. 1993
    1992 Pancreatic and component transplantation for type I diabetesClinical Immunology Newsletter.  12:133-138. 1992

    Chapter

    Year Title Altmetric
    2014 Surgical management of gastroesophageal varices.  205-232. 2014

    Research Overview

  • pediatric and adult liver transplantation, complex hepatobiliary surgery, ischemia reperfusion injury, xenotransplantation
  • Principal Investigator On

  • Private Grant  awarded by ORGANOX LIMITED 2016 - 2021
  • Private Grant  awarded by UNITED THERAPEUTICS CORPORATION 2015 - 2021
  • Private Grant  awarded by EMMES CORPORATION 2008 - 2013
  • Private Grant  awarded by APOIMMUNE, INC. 2010 - 2013
  • Investigator On

  • UAB Center for Clinical and Translational Science (CCTS) (3 Linked Awards UL1, KL2, TL1)  awarded by National Center for Advancing Translational Sciences/NIH/DHHS 2015 - 2019
  • Private Grant  awarded by BOSTON SCIENTIFIC CORPORATION 2016 - 2019
  • Private Grant  awarded by MERIT MEDICAL (*) 2012 - 2019
  • UAB 1356: A Phase II Randomized Multicenter Placebo-Controlled Blinded Study of Sorafenib Adjuvant Therapy in High Risk Orthotopic Liver Transplant (OLT) Recipients with Hepatocellular Carcinoma (HCC)  awarded by University of California, Los Angeles 2015 - 2018
  • ACRIN 6690: A Prospective, Multi-Center Comparison of Multiphase Contrast-Enhanced CT and Multiphase Contrast-Enhanced MRI for Diagnosis of Hepatocellular Carcinoma and Liver Transplant Allocation (R10-122)  awarded by American College of Radiology Imaging Network 2014 - 2017
  • Pre-Transplant Infectious Diseases Evaluation Clinic  awarded by UNIVERSITY OF ALABAMA HEALTH SERVICES FOUNDATION 2014 - 2016
  • UAB 1356 - A Phase II Randomized Multicenter Placebo-Controlled Blinded Study of Sorafenib Adjuvant Therapy in High Risk Orthotropic Liver Transplant (OLT) Recipients with Hepatocellular Carcinoma (HCC)  awarded by University of California, Los Angeles 2014 - 2015
  • Private Grant  awarded by Society of Gastrointestinal Radiologists 2011 - 2014
  • Private Grant  awarded by VERTEX PHARMACEUTICALS, INC. 2012 - 2014
  • Private Grant  awarded by VITAL THERAPIES, INC 2012 - 2014
  • ACRIN 6690: A Prospective, Multi-Center Comparison of Multiphase Contrast-Enhanced CT and Multiphase Contrast Enhanced MRI for Diagnosis of Hepatocellular Carcinoma and Liver Transplant Allocation (R10-122)  awarded by American College of Radiology Imaging Network 2011 - 2014
  • Education And Training

  • Doctor of Medicine, University of Minnesota-Duluth
  • University of Wisconsin Hospital & Clinics, Internship 1988
  • University of Wisconsin Hospital & Clinics, Residency 1992
  • University of Wisconsin Hospital & Clinics, Postdoctoral Fellowship 1994
  • Full Name

  • Devin Eckhoff
  • Blazerid

  • eckhoff