Selected Publications

Academic Article

Year Title Altmetric
2019 Genome-wide association study identifies novel loci for type 2 diabetes-Attributed end-stage kidney disease in African AmericansHuman Genomics.  13. 2019
2017 A Phase 2, Double-Blind, Placebo-Controlled, Randomized Study of Fresolimumab in Patients With Steroid-Resistant Primary Focal Segmental GlomerulosclerosisKidney International Reports.  2:800-810. 2017
2016 Selecting SNPs informative for African, American Indian and European Ancestry: Application to the Family Investigation of Nephropathy and Diabetes (FIND)BMC Genomics.  17. 2016
2015 Dialysate content and risk of sudden cardiac deathCurrent Opinion in Nephrology and Hypertension.  24:557-562. 2015
2015 Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND)PLoS Genetics.  11. 2015
2014 Nephrotoxic effects of common and emerging drugs of abuseClinical Journal of the American Society of Nephrology.  9:1996-2005. 2014
2014 Quality of life and outcomes in African Americans with CKDJournal of the American Society of Nephrology.  25:1849-1855. 2014
2013 AKI associated with synthetic cannabinoids: A case seriesClinical Journal of the American Society of Nephrology.  8:523-526. 2013
2012 Genetic association and gene-gene interaction analyses in African American dialysis patients with nondiabetic nephropathyAmerican Journal of Kidney Diseases.  59:210-221. 2012
2012 Quality of life and psychosocial factors in African Americans with hypertensive chronic kidney diseaseJournal of Laboratory and Clinical Medicine.  159:4-11. 2012
2011 Elevated depressive affect is associated with adverse cardiovascular outcomes among African Americans with chronic kidney diseaseKidney International.  80:670-678. 2011
2010 Sociodemographic factors contribute to the depressive affect among African Americans with chronic kidney diseaseKidney International.  77:1010-1019. 2010
2009 Genome-wide linkage scans for type 2 diabetes mellitus in four ethnically diverse populations - Significant evidence for linkage on chromosome 4q in African Americans: The family investigation of nephropathy and diabetes research groupDiabetes/Metabolism Research and Reviews.  25:740-747. 2009
2009 Risk of hyperkalemia in nondiabetic patients with chronic kidney disease receiving antihypertensive therapyArchives of Internal Medicine -New Series-.  169:1587-1594. 2009
2008 MYH9 is associated with nondiabetic end-stage renal disease in African AmericansNature Genetics.  40:1185-1192. 2008
2008 The Effect of Peritoneal Dialysate on DXA Bone Densitometry Results in Patients with End-Stage Renal DiseaseJournal of Clinical Densitometry.  11:532-536. 2008
2008 Metabolic Syndrome, Proteinuria, and the Risk of Progressive CKD in Hypertensive African AmericansAmerican Journal of Kidney Diseases.  51:732-740. 2008
2007 Reliability of urinary albumin, total protein, and creatinine assays after prolonged storage: The family investigation of nephropathy and diabetesClinical Journal of the American Society of Nephrology.  2:1156-1162. 2007
2006 Differing effects of antihypertensive drugs on the incidence of diabetes mellitus among patients with hypertensive kidney diseaseArchives of Internal Medicine -New Series-.  166:797-805. 2006
2001 Effect of ramipril vs amlodipine on renal outcomes in hypertensive nephrosclerosis: A Randomized Controlled TrialJournal of the American Medical Association.  285:2719-2728. 2001
2001 Non-anemic homozygous β thalassemia in an african-american family: Association of high fetal hemoglobin levels with β thalassemia allelesAmerican Journal of Hematology.  68:43-50. 2001
2000 Homocysteine Elevation in Sickle Cell DiseaseJournal of the American College of Nutrition.  19:608-612. 2000
2000 Reactive species in sickle cell diseaseAnnals of the New York Academy of Sciences.  899:375-391. 2000
1993 A case study of a recent decline in the dialysis fatality rate.Contributions to Nephrology.  102:59-72. 1993
1992 Lithium toxicity associated with a trichobezoarAnnals of Internal Medicine.  116:739-740. 1992
1990 Peritonitis due to Aspergillus niger: Diagnostic importance of peritoneal eosinophiliaPeritoneal Dialysis International.  10:100-101. 1990
1982 Acetazolamide inhibition of renal γ-glutamyl transpeptidaseBiochemical Pharmacology.  31:3347-3352. 1982
1981 Acetazolamide (Az) inhibition of renal χ-glutamyltransferaseFederation proceedings.  40. 1981
1979 Glutathione inhibition of renal ammonia productionFederation proceedings.  38. 1979
1978 Regulation of renal glutamine utilization by glutathionePhysiologist.  21:120. 1978


Year Title Altmetric
2013 Disorders of calcium, phosphorus, and magnesium.  103-116. 2013

Principal Investigator On

  • Private Grant  awarded by MALLINCKRODT, INC. 2016 - 2020
  • Private Grant  awarded by Genzyme Corporation 2013 - 2015
  • Investigator On

  • Private Grant  awarded by GlaxoSmithKline 2017 - 2022
  • Private Grant  awarded by Pfizer Inc., U.S. Pharmaceuticals Group 2019 - 2021
  • Education And Training

  • Doctor of Medicine, Howard University 1984
  • Emory University Hospital Systems, Internship 1985
  • Emory University Hospital Systems, Residency 1987
  • UC Health - University Hospital, Postdoctoral Fellowship 1991
  • Full Name

  • Denyse Thornley-Brown