Positions

Overview

  • Dr. Chanda received his BSc from University of Calcutta, his MSc from Visva Bharati University, and his PhD from Banaras Hindu University. He completed postdoctoral training at the Morehouse School of Medicine and the University of Alabama at Birmingham. Dr. Chanda also previously held appointments as lecturer at Darjeeling Government College and as research associate at UAB. He has published on cancer gene therapy using recombinant adeno-associated virus vectors and gene modified bone marrow-derived mesenchymal stem cells, and cellular adhesion regulators during cancer metastasis.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2019 Fibronectin on the surface of extracellular vesicles mediates fibroblast invasionAmerican Journal of Respiratory Cell and Molecular Biology.  60:279-288. 2019
    2019 Developmental pathways in the pathogenesis of lung fibrosisMolecular Aspects of Medicine.  65:56-69. 2019
    2019 Modeling fibrosis in three-dimensional organoids reveals new epithelial restraints on fibroblastsAmerican Journal of Respiratory Cell and Molecular Biology.  61:556-557. 2019
    2018 Unique Lipid Signatures of Extracellular Vesicles from the Airways of AsthmaticsScientific Reports.  8. 2018
    2018 Exosomal transfer of mitochondria from airway myeloid-derived regulatory cells to T cellsRedox Biology.  18:54-64. 2018
    2018 Fgf10 Signaling in Lung Development, Homeostasis, Disease, and Repair After Injury.Frontiers in Genetics.  9:418. 2018
    2017 Mesenchymal stem cells expressing osteoprotegerin variants inhibit osteolysis in a murine model of multiple myelomaBlood Advances.  1:2375-2385. 2017
    2017 Fgf10-Hippo Epithelial-Mesenchymal Crosstalk Maintains and Recruits Lung Basal Stem CellsDevelopmental Cell.  43:48-59.e5. 2017
    2017 Effects of cellular methylation on transgene expression and site-specific integration of adeno-associated virusGenes.  8. 2017
    2017 Exosomes in immunoregulation of chronic lung diseasesAllergy.  72:534-544. 2017
    2016 Developmental Reprogramming in Mesenchymal Stromal Cells of Human Subjects with Idiopathic Pulmonary FibrosisScientific Reports.  6. 2016
    2015 Endostatin: A novel inhibitor of androgen receptor function in prostate cancerProceedings of the National Academy of Sciences.  112:1392-1397. 2015
    2015 Breast cancer subtypes predispose the site of distant metastasesAmerican Journal of Clinical Pathology.  143:471-478. 2015
    2015 Variants of osteoprotegerin lacking trail binding for therapeutic bone remodeling in osteolytic malignanciesCell Growth and Differentiation.  13:819-827. 2015
    2014 Anterior gradient protein-2 is a regulator of cellular adhesion in prostate cancerPLoS ONE.  9. 2014
    2012 Depletion of plasmacytoid dendritic cells inhibits tumor growth and prevents bone metastasis of breast cancer cellsJournal of Immunology.  189:4258-4265. 2012
    2012 Noggin is novel inducer of mesenchymal stem cell adipogenesis: Implications for bone health and obesityJournal of Biological Chemistry.  287:12241-12249. 2012
    2011 Conditionally replicating adenovirus expressing TIMP2 increases survival in a mouse model of disseminated ovarian cancerPLoS ONE.  6. 2011
    2011 LL-37 as a therapeutic target for late stage prostate cancerProstate.  71:659-670. 2011
    2010 Therapeutic potential of adult bone marrow-derived mesenchymal stem cells in diseases of the skeletonJournal of Cellular Biochemistry.  111:249-257. 2010
    2009 Therapeutic potential of adult bone marrow-derived mesenchymal stem cells in prostate cancer bone metastasisClinical Cancer Research.  15:7175-7185. 2009
    2009 Tumoristatic effects of endostatin in prostate cancer is dependent on androgen receptor statusProstate.  69:1055-1066. 2009
    2009 Death receptor 5 agonist TRA8 in combination with the bisphosphonate zoledronic acid attenuated the growth of breast cancer metastasisCancer Biology and Therapy.  8:1109-1116. 2009
    2008 Therapeutic potential of mesenchymal stem cells producing interferon-α in a mouse melanoma lung metastasis modelSTEM CELLS.  26:2332-2338. 2008
    2008 Telomere maintenance in laser capture microdissection - Purified Barrett's adenocarcinoma cells and effect of telomerase inhibition in vivoClinical Cancer Research.  14:4971. 2008
    2008 Cancer gene therapy using mesenchymal stem cells expressing interferon-β in a mouse prostate cancer lung metastasis modelGene Therapy.  15:1446-1453. 2008
    2008 Therapeutic potential of genetically modified mesenchymal stem cellsGene Therapy.  15:711-715. 2008
    2008 Systemic osteoprotegerin gene therapy restores tumor-induced bone loss in a therapeutic model of beast cancer bone metastasisMolecular Therapy.  16:871-878. 2008
    2007 Effects of sustained antiangiogenic therapy in multistage prostate cancer in TRAMP ,modelCancer Research.  67:5789-5797. 2007

    Research Overview

  • Dr. Chanda's research interests relate to developmental reprogramming during tissue injury repair, gene and cell based therapies, pulmonary fibrosis, and lung cancer.
  • Education And Training

  • Banaras Hindu University, Other
  • Morehouse School of Medicine, Postdoctoral Research
  • Visva Bharati University, Other
  • Master of Science in Public Health, University of Alabama at Birmingham 2016
  • Doctor of Science in Medical Basic Sciences, Banaras Hindu University 2001
  • Master of Life Sciences in Medical Basic Sciences, Visva-Bharati 1994
  • Bachelor of Science or Mathematics in Medical Basic Sciences, University of Calcutta 1992
  • Full Name

  • Diptiman Chanda