Positions

Overview

  • Christianne Strang is a board-certified art therapist with 25 years of clinical art therapy experience. She earned her MA in Art Therapy from Vermont College of Norwich University in 1987, and has served as treasurer for the American Art Therapy Association and for the Art Therapy Credentials Board. In July 2015 she will take office as the President-Elect of the American Art Therapy Association. Dr. Strang received her PhD in Behavioral Neuroscience from the University of Alabama at Birmingham in 2004, followed by a position as a Research Associate in the lab of Dr. Kent Keyser. She joined the Faculty of the Department of Vision Sciences at UAB in May 2011. Dr. Strang’s primary research focus is the study of the expression patterns and physiological roles of nicotinic and muscarinic acetylcholine receptors in the retina. Her work uses RT-PCR, immunohistochemistry, and fluorescence microscopy to identify the complement of AChR mRNA transcripts and proteins in the mammalian retina, and patch clamp electrophysiology to characterize the effects of AChR activation on basic retinal processing. Recently, Dr. Strang has begun extending her research towards increased clinical relevance using molecular, imaging, and electrophysiological techniques to characterize the pathophysiological changes in the retinas of transgenic mice that serve as a model for Alzheimer’s disease. She is actively involved in the didactic and laboratory training of students in the Departments of Vision Sciences, Psychology, and Neurobiology, and received the President’s Award for Excellence in Teaching in March of 2015. She is co-course director for the UAB introductory undergraduate and graduate introductory neurobiology courses held at the Dauphin Island Sea Lab.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2018 Somatic gene editing of GUCY2D by AAV-CRISPR/Cas9 alters retinal structure and function in mouse and macaque.Human Gene Therapy2018
    2018 Effects of tDCS-like electrical stimulation on retinal ganglion cells.Eye and Brain.  10:65-78. 2018
    2017 Retinal changes in the Tg-SwDI mouse model of Alzheimer's disease.Neuroscience.  354:43-53. 2017
    2016 Unfolded protein response-induced dysregulation of calcium homeostasis promotes retinal degeneration in rat models of autosomal dominant retinitis pigmentosa.Cell Death and Disease.  7:e2085. 2016
    2016 Novel Methodology for Creating Macaque Retinas with Sortable Photoreceptors and Ganglion Cells.Frontiers in Neuroscience.  10:551. 2016
    2015 Nicotinic and muscarinic acetylcholine receptors shape ganglion cell response properties.Journal of Neurophysiology.  113:203-217. 2015
    2014 Central projections of intrinsically photosensitive retinal ganglion cells in the macaque monkeyJournal of Comparative Neurology.  522:2231-2248. 2014
    2014 Central projections of intrinsically photosensitive retinal ganglion cells in the macaque monkey.Journal of Comparative Neurology.  522:2231-2248. 2014
    2014 Acetylcholine receptors in the retinas of the α7 nicotinic acetylcholine receptor knockout mouse.Molecular Vision.  20:1328-1356. 2014
    2011 Two-photon excited autofluorescence imaging of freshly isolated frog retinas.Biomedical Optics Express.  2:1494-1503. 2011
    2010 Parallel optical monitoring of visual signal propagation from the photoreceptors to the inner retina layers.Optics Letters.  35:1810-1812. 2010
    2010 Muscarinic acetylcholine receptor localization and activation effects on ganglion response properties.Investigative Ophthalmology & Visual Science.  51:2778-2789. 2010
    2009 Nicotinic acetylcholine receptor subunits in rhesus monkey retina.Investigative Ophthalmology & Visual Science.  50:1408-1415. 2009
    2008 Role of acetylcholine in nitric oxide production in the salamander retina.Journal of Comparative Neurology.  507:1952-1963. 2008
    2007 Selective modulation of scleral proteoglycan mRNA levels during minus lens compensation and recovery.Molecular Vision.  13:1878-1886. 2007
    2007 Nicotinic acetylcholine receptor expression by directionally selective ganglion cells.Visual Neuroscience.  24:523-533. 2007
    2007 Strychnine, but not PMBA, inhibits neuronal nicotinic acetylcholine receptors expressed by rabbit retinal ganglion cells.Visual Neuroscience.  24:503-511. 2007
    2007 Expression of alpha 7 nicotinic acetylcholine receptors by bipolar, amacrine, and ganglion cells of the rabbit retina.Journal of Histochemistry and Cytochemistry.  55:461-476. 2007
    2005 Rabbit retinal ganglion cells express functional alpha7 nicotinic acetylcholine receptors.American Journal of Physiology - Cell Physiology.  289:C644-C655. 2005
    2005 Directionally selective ganglion cells in rabbit retina express functional A7 nAChRsInvestigative Ophthalmology & Visual Science.  46. 2005
    2005 Low-dose strychnine and its effects on alpha 7 nicotinic receptor functionInvestigative Ophthalmology & Visual Science.  46. 2005
    2003 Rabbit retinal ganglion cell responses to nicotine can be mediated by beta2-containing nicotinic acetylcholine receptors.Visual Neuroscience.  20:651-662. 2003
    2003 Activation of the cGMP/nitric oxide signal transduction system by nicotine in the retina.Visual Neuroscience.  20:165-176. 2003

    Chapter

    Year Title Altmetric
    2016 The Role of Acetylcholine and its Receptors in Retinal Processing 2016
    2010 Optical imaging of cancer: Enhancing detection and resection.  3-24. 2010
    2010 The Role of Acetylcholine and its Receptors in Retinal Processing.  153-153. 2010

    Research Overview

  • The expression and function of acetylcholine receptors in the retina, retinal anatomy, retinal development, developmental neuroscience, behavioral neuroscience
  • Teaching Activities

  • PY420 - Special Topics (Fall Term 2018) 2018
  • PY453 - Adv Behavioral Neuroscience (Fall Term 2018) 2018
  • PY653 - Foundations Behav Neuroscience (Fall Term 2018) 2018
  • PY753 - Foundations Behav Neuroscience (Fall Term 2018) 2018
  • PY791 - Special Topics (Summer Term 2018) 2018
  • PY791 - Special Topics (Summer Term 2018) 2018
  • GBS730 - Intro to Neurobio (Summer Term 2018) 2018
  • GBS730 - Intro to Neurobio (Summer Term 2018) 2018
  • PY426 - Creative Arts Therapies (Spring Term 2018) 2018
  • PY457 - Neural Measurement Lab (Spring Term 2018) 2018
  • GBS730 - Intro to Neurobio (Fall Term 2017) 2017
  • PY353 - Behavioral Neuroscience (Fall Term 2017) 2017
  • PY353L - Behavioral Neuroscience Lab (Fall Term 2017) 2017
  • PY791 - Special Topics (Summer Term 2017) 2017
  • PY420 - Special Topics (Spring Term 2017) 2017
  • GBS730 - Intro to Neurobio (Fall Term 2016) 2016
  • PY353 - Behavioral Neuroscience (Fall Term 2016) 2016
  • PY791 - Special Topics (Summer Term 2016) 2016
  • GBS714 - Developmental Neurosci (Spring Term 2016) 2016
  • PY420 - Special Topics (Spring Term 2016) 2016
  • PY791 - Special Topics (Spring Term 2016) 2016
  • GBS730 - Intro to Neurobio (Fall Term 2015) 2015
  • PY353 - Behavioral Neuroscience (Fall Term 2015) 2015
  • VIS729 - Intro to Neurobio/Marine Bio (Fall Term 2015) 2015
  • GBS714 - Developmental Neurosci (Spring Term 2015) 2015
  • PY101 - Intro to Psychology (Spring Term 2015) 2015
  • PY420 - Special Topics (Spring Term 2015) 2015
  • VS212 - Visual Development (Fall Term 2014) 2014
  • GBS730 - Intro to Neurobio (Fall Term 2014) 2014
  • VIS429 - Intro to Neurobiology (Fall Term 2014) 2014
  • VIS729 - Intro to Neurobio/Marine Bio (Fall Term 2014) 2014
  • GBS714 - Developmental Neurosci (Spring Term 2014) 2014
  • PY353 - Behavioral Neuroscience (Fall Term 2013) 2013
  • VIS729 - Intro to Neurobio/Marine Bio (Fall Term 2013) 2013
  • GBS714 - Developmental Neurosci (Spring Term 2013) 2013
  • PY353 - Behavioral Neuroscience (Fall Term 2012) 2012
  • VIS729 - Intro to Neurobio/Marine Bio (Fall Term 2012) 2012
  • VIS729 - Intro to Neurobio/Marine Bio (Summer Term 2012) 2012
  • PY353 - Behavioral Neuroscience (Fall Term 2011) 2011
  • Education And Training

  • Doctor of Philosophy in Psychology, University of Alabama at Birmingham
  • Full Name

  • Christianne Strang
  • Blazerid

  • cwilk