Positions

Selected Publications

Academic Article

Year Title Altmetric
2018 Novel fatty acyl apoE mimetic peptides have increased potency to reduce plasma cholesterol in mice and macaques.Journal of Lipid Research.  59:2075-2083. 2018
2018 The Apolipoprotein E Mimetic Peptide AEM-2 Attenuates Mitochondrial Injury And Apoptosis In Human THP-1 Macrophages.Current topics in peptide & protein research.  19:15-25. 2018
2017 Cholesterol reduction and macrophage function: role of paraoxonases.Current Opinion in Lipidology.  28:397-402. 2017
2017 High-Density Lipoprotein Regulation of Mitochondrial Function.Advances in Experimental Medicine and Biology.  982:407-429. 2017
2016 High-density lipoprotein, mitochondrial dysfunction and cell survival mechanisms.Chemistry and Physics of Lipids.  199:161-169. 2016
2016 Independent effects of early-life experience and trait aggression on cardiovascular function.AJP - Regulatory, Integrative and Comparative Physiology.  311:R272-R286. 2016
2016 Apolipoprotein Mimetic Peptides as Modulators of Lipoprotein Function.Protein and Peptide Letters.  23:1024-1031. 2016
2015 Recent developments in modulating atherogenic lipoproteins.Current Opinion in Lipidology.  26:369-375. 2015
2015 Bioenergetic programming of macrophages by the apolipoprotein A-I mimetic peptide 4F.Biochemical Journal.  467:517-527. 2015
2015 Early changes in vascular reactivity in response to56Fe irradiation in ApoE-/- miceActa Astronautica.  108:40-45. 2015
2014 Anti-inflammatory and cholesterol-reducing properties of apolipoprotein mimetics: a review.Journal of Lipid Research.  55:2007-2021. 2014
2014 L-4F inhibits lipopolysaccharide-mediated activation of primary human neutrophils.Inflammation.  37:1401-1412. 2014
2014 Inhibitors of arachidonate-regulated calcium channel signaling suppress triggered activity induced by the late sodium current.European Journal of Pharmacology.  724:92-101. 2014
2013 Anti-inflammatory mechanisms of apolipoprotein A-I mimetic peptide in acute respiratory distress syndrome secondary to sepsis.PLoS ONE.  8:e64486. 2013
2012 Regulation of pattern recognition receptors by the apolipoprotein A-I mimetic peptide 4F.Arteriosclerosis, Thrombosis, and Vascular Biology.  32:2631-2639. 2012
2012 Preservation of biological function despite oxidative modification of the apolipoprotein A-I mimetic peptide 4F.Journal of Lipid Research.  53:1576-1587. 2012
2011 HDL Mimetic Peptide Administration Improves Left Ventricular Filling and Cardiac output in Lipopolysaccharide-Treated Rats.Journal of Clinical and Experimental Cardiology.  2. 2011
2011 Acyloxy nitroso compounds as nitroxyl (HNO) donors: kinetics, reactions with thiols, and vasodilation properties.Journal of Medicinal Chemistry.  54:1059-1070. 2011
2010 The apolipoprotein A-I mimetic peptide 4F prevents defects in vascular function in endotoxemic rats.Journal of Lipid Research.  51:2695-2705. 2010
2010 Dietary flavonoid quercetin stimulates vasorelaxation in aortic vessels.Free Radical Biology and Medicine.  49:339-347. 2010
2010 Potential for chlorine gas-induced injury in the extrapulmonary vasculature.Proceedings of the American Thoracic Society.  7:290-293. 2010
2010 Apolipoprotein A-I mimetic 4F alters the function of human monocyte-derived macrophages.American Journal of Physiology - Cell Physiology.  298:C1538-C1548. 2010
2010 Anti-inflammatory and recycling properties of an apolipoprotein mimetic peptide, Ac-hE18A-NH(2).Atherosclerosis.  208:134-141. 2010
2010 ApoE mimetic peptide reduces plasma lipid hydroperoxide content with a concomitant increase in HDL paraoxonase activity.Advances in Experimental Medicine and Biology.  660:1-4. 2010
2009 Apolipoprotein A-I mimetic peptide treatment inhibits inflammatory responses and improves survival in septic rats.AJP - Heart and Circulatory Physiology.  297:H866-H873. 2009
2009 Pulmonary ozone exposure induces vascular dysfunction, mitochondrial damage, and atherogenesis.AJP - Lung Cellular and Molecular Physiology.  297:L209-L216. 2009
2009 Protein O-GlcNAcylation: a new signaling paradigm for the cardiovascular system.AJP - Heart and Circulatory Physiology.  296:H13-H28. 2009
2009 Vasculoprotective Effects of Apolipoprotein Mimetic Peptides: An Evolving Paradigm In Hdl Therapy (Vascular Disease Prevention, In Press.).Vascular Disease Prevention.  6:122-130. 2009
2008 HDL therapy for cardiovascular diseases: the road to HDL mimetics.Current Atherosclerosis Reports.  10:405-412. 2008
2006 Atherosclerosis and vascular disease: effects of peptide mimetics of apolipoproteins.Current Pharmaceutical Biotechnology.  7:235-240. 2006
2006 Synthetic peptides: managing lipid disorders.Current Opinion in Lipidology.  17:233-237. 2006
2005 Antihypertensive and cognitive effects of grape polyphenols in estrogen-depleted, female, spontaneously hypertensive rats.AJP - Regulatory, Integrative and Comparative Physiology.  289:R771-R775. 2005
2005 Evidence of cardiovascular protection by moderate alcohol: role of nitric oxide.Free Radical Biology and Medicine.  39:540-548. 2005
2005 Inhibition of lipopolysaccharide-induced inflammatory responses by an apolipoprotein AI mimetic peptide.Circulation Research.  97:236-243. 2005
2005 Apolipoprotein E mimetic Peptide dramatically lowers plasma cholesterol and restores endothelial function in watanabe heritable hyperlipidemic rabbits.Circulation.  111:3112-3118. 2005
2005 Assessing NO-dependent vasodilatation using vessel bioassays at defined oxygen tensions.Methods in Enzymology.  396:553-568. 2005
2004 L-Arginine inhibits xanthine oxidase-dependent endothelial dysfunction in hypercholesterolemia.FEBS Letters.  561:94-98. 2004
2003 The neointimal response to endovascular injury is increased in obese Zucker rats.Diabetes, Obesity and Metabolism.  5:415-423. 2003
2003 Vasoactivity of S-nitrosohemoglobin: role of oxygen, heme, and NO oxidation states.Blood.  101:4408-4415. 2003
2002 Nitrolinoleate, a nitric oxide-derived mediator of cell function: synthesis, characterization, and vasomotor activity.Proceedings of the National Academy of Sciences.  99:15941-15946. 2002
2002 Myeloperoxidase, a leukocyte-derived vascular NO oxidase.Science.  296:2391-2394. 2002
2001 Oxygen radical inhibition of nitric oxide-dependent vascular function in sickle cell disease.Proceedings of the National Academy of Sciences.  98:15215-15220. 2001
2001 Endothelial transcytosis of myeloperoxidase confers specificity to vascular ECM proteins as targets of tyrosine nitration.Journal of Clinical Investigation.  108:1759-1770. 2001
2001 Endothelial dysfunction is induced by proinflammatory oxidant hypochlorous acidAJP - Heart and Circulatory Physiology.  281. 2001
2001 Endothelial dysfunction is induced by proinflammatory oxidant hypochlorous acid.AJP - Heart and Circulatory Physiology.  281:H1469-H1475. 2001
2001 L-arginine chlorination products inhibit endothelial nitric oxide production.Journal of Biological Chemistry.  276:27159-27165. 2001
2001 Enhanced antioxidant activity after chlorination of quercetin by hypochlorous acid.Alcoholism: Clinical and Experimental Research.  25:434-443. 2001
2001 Human angiotensin II type 1 receptor isoforms encoded by messenger RNA splice variants are functionally distinct.Molecular Endocrinology -Baltimore-.  15:281-293. 2001
2001 Formation of novel bioactive metabolites from the reactions of pro-inflammatory oxidants with polyphenolics.BioFactors.  15:79-81. 2001
2000 Elevated sympathetic activity contributes to hypertension and salt sensitivity in diabetic obese Zucker rats.Hypertension.  35:403-408. 2000
1999 Chemiluminescent detection of oxidants in vascular tissue. Lucigenin but not coelenterazine enhances superoxide formation.Circulation Research.  84:1203-1211. 1999
1999 Biological aspects of reactive nitrogen species.BBA - Biochimica et Biophysica Acta.  1411:385-400. 1999
1999 Nitric oxide donor generation from reactions of peroxynitrite.Methods in Enzymology.  301:288-298. 1999
1998 Captopril treatment and its withdrawal prevents impairment of endothelium-dependent responses in the spontaneously hypertensive rat.Clinical and experimental hypertension.  20:847-866. 1998
1998 Nitrosation of uric acid by peroxynitrite. Formation of a vasoactive nitric oxide donor.Journal of Biological Chemistry.  273:24491-24497. 1998
1997 Formation of the NO donors glyceryl mononitrate and glyceryl mononitrite from the reaction of peroxynitrite with glycerol.Biochemical Journal.  328 ( Pt 2):517-524. 1997
1997 No role for NO in estrogen-mediated vasoprotection?Circulation.  96:2769-2771. 1997
1997 The interplay of nitric oxide and peroxynitrite with signal transduction pathways: implications for disease.Seminars in Perinatology.  21:351-366. 1997
1997 Estrogen restores endothelial cell function in an experimental model of vascular injury.Circulation.  96:1624-1630. 1997
1997 Nitric oxide, free radicals and cell signalling in cardiovascular disease.Biochemical Society Transactions.  25:925-929. 1997
1997 Gender and cardiovascular disease recent insights.Trends in Cardiovascular Medicine.  7:94-100. 1997
1997 Immunoglobulin light chain alters mesangial cell calcium homeostasisAJP - Renal Physiology.  272. 1997
1997 Immunoglobulin light chain alters mesangial cell calcium homeostasis.American Journal of Physiology.  272:F319-F324. 1997
1996 Circulating plasma xanthine oxidase contributes to vascular dysfunction in hypercholesterolemic rabbits.Proceedings of the National Academy of Sciences.  93:8745-8749. 1996
1995 A functional comparison of the rat type-1 angiotensin II receptors (AT1AR and AT1BR).Regulatory Peptides.  60:135-147. 1995
1995 Hyperglycemia alters cytoplasmic Ca2+ responses to capacitative Ca2+ influx in rat aortic smooth muscle cells.American Journal of Physiology.  269:C1482-C1488. 1995
1995 Calcium-sensitive chloride channels in vascular smooth muscle cells.Proceedings of the Society for Experimental Biology and Medicine.  208:255-262. 1995
1995 Oxygen radical-nitric oxide reactions in vascular diseases.Advances in Pharmacology.  34:45-69. 1995
1994 Calcium-mobilizing agonists stimulate anion fluxes in cultured endothelial cells from human umbilical vein.Journal of Membrane Biology.  142:171-179. 1994
1994 Extensive nitration of protein tyrosines in human atherosclerosis detected by immunohistochemistry.Biological chemistry Hoppe-Seyler.  375:81-88. 1994
1994 Superoxide and peroxynitrite in atherosclerosis.Proceedings of the National Academy of Sciences.  91:1044-1048. 1994

Chapter

Year Title Altmetric
2010 HDL mimetic peptides: Novel therapeutic strategies for the treatment of inflammatory vascular disease.  179-197. 2010

Education And Training

  • Doctor of Philosophy in Physiology, Pathology, and Related Sciences, University of Illinois System : Urbana-Champaign
  • Master of Life Sciences in Physiology, Pathology and Related Sciences, University of Illinois System : Urbana-Champaign
  • Full Name

  • C White
  • Blazerid

  • crwhite