Positions

Selected Publications

Academic Article

Year Title Altmetric
2018 Characterization of the pgf operon involved in the posttranslational modification of Streptococcus mutans surface proteinsScientific Reports.  8. 2018
2018 Antigen I/II mediates interactions between Streptococcus mutans and Candida albicansOral Microbiology and Immunology.  33:283-291. 2018
2018 Glucan binding protein C of Streptococcus mutans mediates both sucrose-independent and sucrose-dependent adherenceInfection and Immunity.  86. 2018
2018 Glycoprotein 340 in mucosal immunity and ocular surfaceOcular Surface.  16:282-288. 2018
2015 Interaction of βa3-crystallin with deamidated mutants of αa-and bcrystallinsPLoS ONE.  10. 2015
2015 Variants of osteoprotegerin lacking trail binding for therapeutic bone remodeling in osteolytic malignanciesCell Growth and Differentiation.  13:819-827. 2015
2014 The calcium-induced conformation and glycosylation of scavenger-rich cysteine repeat (SRCR) domains of glycoprotein 340 influence the high affinity interaction with antigen I/II homologsJournal of Biological Chemistry.  289:21877-21887. 2014
2014 The study of lipid peroxidation, liver enzymes and antioxidantstatus inlufenuron treated mice, mus musculus speciesInternational Journal of ChemTech Research.  6:5321-5328. 2014
2013 Structural and functional characterization of the mumps virus phosphoproteinJournal of Virology.  87:7558-7568. 2013
2013 Cloning, expression and purification of the SRCR domains of glycoprotein 340Protein Expression and Purification.  90:67-73. 2013
2012 Sidedness of interfacial arginine residues and anti-atherogenicity of apolipoprotein A-I mimetic peptidesJournal of Lipid Research.  53:849-858. 2012
2011 Structural and biochemical characterization of Staphylococcus aureus clumping factor B/ligand interactionsJournal of Biological Chemistry.  286:25963-25972. 2011
2011 Crystal structure of the C-terminal region of Streptococcus mutans antigen I/II and characterization of salivary agglutinin adherence domainsJournal of Biological Chemistry.  286:21657-21666. 2011
2010 Bacteriophage hyaluronidase effectively inhibits growth, migration and invasion by disrupting hyaluronan-mediated Erk1/2 activation and RhoA expression in human breast carcinoma cellsCancer Letters.  298:238-249. 2010
2010 Elongated fibrillar structure of a streptococcal adhesin assembled by the high-affinity association of α- and PPII-helicesProceedings of the National Academy of Sciences.  107:5983-5988. 2010
2010 The changing faces of Streptococcus antigen I/II polypeptide family adhesins: MicroReviewMicrobiological sciences.  77:276-286. 2010
2008 TLR4-mediated activation of dendritic cells by the heat shock protein DnaK from Francisella tularensisJournal of Leukocyte Biology.  84:1434-1446. 2008
2007 Structural adaptation of an interacting non-native C-terminal helical extension revealed in the crystal structure of NAD+ synthetase from Bacillus anthracisActa Crystallographica Section D: Biological Crystallography.  63:891-905. 2007
2007 Protein crystallization.Methods in Molecular Biology.  383:337-349. 2007
2003 Replication of chimeric human immunodeficiency virus type 1 (HIV-1) containing HIV-2 integrase (IN): Naturally selected mutations in IN augment DNA synthesisJournal of Virology.  77:11050-11059. 2003
2003 A structural model for the inhibition of calpain by calpastatin: Crystal structures of the native domain VI of calpain and its complexes with calpastatin peptide and a small molecule inhibitorJournal of Molecular Biology.  328:131-146. 2003
2002 A novel variant of the immunoglobulin fold in surface adhesins of Staphylococcus aureus: Crystal structure of the fibrinogen-binding MSCRAMM, clumping factor AEMBO Journal.  21:6660-6672. 2002
2002 Crystallization and preliminary X-ray crystallographic analysis of Ace: A collagen-binding MSCRAMM from Enterococcus faecalisBBA - Proteins and Proteomics.  1596:173-176. 2002
2001 Structural Organization of the Fibrinogen-binding Region of the Clumping Factor B MSCRAMM of Staphylococcus aureusJournal of Biological Chemistry.  276:44721-44728. 2001
2000 Structure of FKBP12.6 in complex with rapamycinActa Crystallographica Section D: Biological Crystallography.  56:266-271. 2000
2000 Novel fold and assembly of the repetitive B region of the Staphylococcus aureus collagen-binding surface proteinStructure.  8:67-78. 2000
1999 Erratum: Trench-shaped binding sites promote multiple classes of interactions between collagen and the adherence receptors, α1β1 integrin and Staphylococcus aureus Cna MSCRAMM (Journal of Biological Chemistry (1999) 274 (24906-24913))Journal of Biological Chemistry.  274:28836. 1999
1999 Trench-shaped binding sites promote multiple classes of interactions between collagen and the adherence receptors, alpha(1)beta(1) integrin and Staphylococcus aureus Cna MSCRAMM. (vol 274, pg 24906, 1999)Journal of Biological Chemistry.  274:28836-28836. 1999
1999 Trench-shaped binding sites promote multiple classes of interactions between collagen and the adherence receptors, α1β1 integrin and Staphylococcus aureus Cna MSCRAMMJournal of Biological Chemistry.  274:24906-24913. 1999
1999 Crystallization and preliminary X-ray analysis of B-domain fragments of a Staphylococcus aureus collagen-binding proteinActa Crystallographica Section D: Biological Crystallography.  55:525-527. 1999
1999 Crystallization of ClfA and ClfB fragments: The fibrinogen-binding surface proteins of Staphylococcus aureusActa Crystallographica Section D: Biological Crystallography.  55:554-556. 1999
1998 Domain structure of the Staphylococcus aureus collagen adhesinBiochemistry.  37:15423-15433. 1998

Education And Training

  • Doctor of Philosophy Level Degree in Molecular Biology, 1995
  • Full Name

  • Champion Deivanayagam