Positions

Selected Publications

Academic Article

Year Title Altmetric
2018 Characterization of the pgf operon involved in the posttranslational modification of Streptococcus mutans surface proteins 2018
2018 Antigen I/II mediates interactions between Streptococcus mutans and Candida albicans 2018
2018 Glucan binding protein C of Streptococcus mutans mediates both sucrose-independent and sucrose-dependent adherence 2018
2018 Glycoprotein 340 in mucosal immunity and ocular surface 2018
2015 Interaction of βa3-crystallin with deamidated mutants of αa-and bcrystallins 2015
2015 Variants of osteoprotegerin lacking trail binding for therapeutic bone remodeling in osteolytic malignancies 2015
2014 The calcium-induced conformation and glycosylation of scavenger-rich cysteine repeat (SRCR) domains of glycoprotein 340 influence the high affinity interaction with antigen I/II homologs 2014
2014 The study of lipid peroxidation, liver enzymes and antioxidantstatus inlufenuron treated mice, mus musculus species 2014
2013 Structural and functional characterization of the mumps virus phosphoprotein 2013
2013 Cloning, expression and purification of the SRCR domains of glycoprotein 340 2013
2012 Sidedness of interfacial arginine residues and anti-atherogenicity of apolipoprotein A-I mimetic peptides 2012
2011 Structural and biochemical characterization of Staphylococcus aureus clumping factor B/ligand interactions 2011
2011 Crystal structure of the C-terminal region of Streptococcus mutans antigen I/II and characterization of salivary agglutinin adherence domains 2011
2010 Bacteriophage hyaluronidase effectively inhibits growth, migration and invasion by disrupting hyaluronan-mediated Erk1/2 activation and RhoA expression in human breast carcinoma cells 2010
2010 Elongated fibrillar structure of a streptococcal adhesin assembled by the high-affinity association of α- and PPII-helices 2010
2010 The changing faces of Streptococcus antigen I/II polypeptide family adhesins: MicroReview 2010
2008 TLR4-mediated activation of dendritic cells by the heat shock protein DnaK from Francisella tularensis 2008
2007 Structural adaptation of an interacting non-native C-terminal helical extension revealed in the crystal structure of NAD+ synthetase from Bacillus anthracis 2007
2007 Protein crystallization. 2007
2003 Replication of chimeric human immunodeficiency virus type 1 (HIV-1) containing HIV-2 integrase (IN): Naturally selected mutations in IN augment DNA synthesis 2003
2003 A structural model for the inhibition of calpain by calpastatin: Crystal structures of the native domain VI of calpain and its complexes with calpastatin peptide and a small molecule inhibitor 2003
2002 A novel variant of the immunoglobulin fold in surface adhesins of Staphylococcus aureus: Crystal structure of the fibrinogen-binding MSCRAMM, clumping factor A 2002
2002 Crystallization and preliminary X-ray crystallographic analysis of Ace: A collagen-binding MSCRAMM from Enterococcus faecalis 2002
2001 Structural Organization of the Fibrinogen-binding Region of the Clumping Factor B MSCRAMM of Staphylococcus aureus 2001
2000 Structure of FKBP12.6 in complex with rapamycin 2000
2000 Novel fold and assembly of the repetitive B region of the Staphylococcus aureus collagen-binding surface protein 2000
1999 Erratum: Trench-shaped binding sites promote multiple classes of interactions between collagen and the adherence receptors, α1β1 integrin and Staphylococcus aureus Cna MSCRAMM (Journal of Biological Chemistry (1999) 274 (24906-24913)) 1999
1999 Trench-shaped binding sites promote multiple classes of interactions between collagen and the adherence receptors, alpha(1)beta(1) integrin and Staphylococcus aureus Cna MSCRAMM. (vol 274, pg 24906, 1999) 1999
1999 Trench-shaped binding sites promote multiple classes of interactions between collagen and the adherence receptors, α1β1 integrin and Staphylococcus aureus Cna MSCRAMM 1999
1999 Crystallization and preliminary X-ray analysis of B-domain fragments of a Staphylococcus aureus collagen-binding protein 1999
1999 Crystallization of ClfA and ClfB fragments: The fibrinogen-binding surface proteins of Staphylococcus aureus 1999
1998 Domain structure of the Staphylococcus aureus collagen adhesin 1998

Investigator On

  • Bacterial Second Messenger Mediated Virulence Regulation in Streptococcus Mutans  awarded by National Institute of Dental and Craniofacial Research/NIH/DHHS 2019 - 2024
  • Small Molecule Inhibitors of Carciogenic Biofilms  awarded by National Institute of Dental and Craniofacial Research/NIH/DHHS 2018 - 2023
  • Insights into the Lid Margin: Characterization of Membrane Associated Mucins in Ocular Surface Disease  awarded by National Eye Institute/NIH/DHHS 2018 - 2023
  • Glycosylation and Biogenesis of Streptococcal Adhesins  awarded by National Institute of Dental and Craniofacial Research/NIH/DHHS 2018 - 2023
  • Comprehensive Cancer Center Core Support Grant  awarded by National Cancer Institute/NIH/DHHS 2019 - 2021
  • Comprehensive Cancer Center Core Support Grant  awarded by National Cancer Institute/NIH/DHHS 2017 - 2019
  • Comprehensive Cancer Center Core Support Grant  awarded by National Cancer Institute/NIH/DHHS 2016 - 2017
  • A Comprehensive Evaluation of Microgravity Protein Crystallization  awarded by NASA - National Aeronautics & Space Administration 2011 - 2016
  • Active - Structural Biology SF X-Ray Crystallography - Comprehensive Cancer Center Core Support Grant  awarded by National Cancer Institute/NIH/DHHS 2011 - 2016
  • Comprehensive Cancer Center Core Support Grant  awarded by National Cancer Institute/NIH/DHHS 2011 - 2016
  • Mechanism of Cell Surface Assembly Catalyzed by Sortases  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS 2008 - 2013
  • Full Name

  • Champion Deivanayagam