Inflammation, Immunology and Immunotherapeutics

Program

The goal of the Inflammation, Immunology, and Immunotherapeutics Program is to grow and accelerate research in basic immunology and interactions of cancer and the immune system by developing novel approaches for the treatment of leukemia/lymphoma and solid tumors, and by understanding and exploiting the basic biology of the immune system’s responses to cancers.

People

Program Members

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    Ballesteros-Tato Ph.D., Andre, Associate Scientist

    Dr. Ballesteros-Tato completed his Ph.D. in Molecular Biology at the Autonoma University of Madrid in Spain in July 2007. In his Ph.D. thesis work, he studied the role of the cell cycle inhibitor p21 and the apoptosis-inducing Fas receptor in controlling immunological tolerance in different murine and human autoimmune diseases. Beginning in March of 2008, he joined the laboratory of Dr. Troy Randall at Trudeau Institute as a postdoctoral fellow, and then later moved with Dr. Randall's lab to th...

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    Britt M.D., William, Senior Scientist

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    Broker, Thomas, Senior Scientist

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    Buchsbaum Ph.D., Donald, Senior Scientist

    My research is focused on the use of monoclonal antibodies that bind cancer cell surface receptors for cancer therapy in combination with chemotherapy agents, Wnt inhibitors, or radiation. This research involves investigation of the mechanisms of enhanced cytotoxicity produced by combination treatment. Orthotopic and metastatic breast, ovarian, and pancreatic cancer xenograft models are being used to optimize therapeutic regimens in collaboration with investigators from the Divisions of Gynecolo...

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    Bullard, Daniel, Senior Scientist

    Dr. Bullard received his undergraduate degree in zoology from Iowa State University and his Ph.D. in genetics from Case Western Reserve University. During his postdoctoral studies in the Department of Human and Molecular Genetics at Baylor College of Medicine in Houston, he initiated research investigating the role of leukocyte/endothelial cell adhesion molecules in inflammatory processes. He joined the Department of Genetics at UAB in 1996.

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    Chow Ph.D., Louise, Senior Scientist

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    Coleman, Carrie B., Associate Scientist

    Carrie B. Coleman obtained her B.S. with a concentration in Microbiology at the University of Tennessee at Martin in 2002. As a graduate student she joined the lab of Dr. Scott Tibbetts in the Department of Microbiology & Immunology at LSU Health Sciences Center – Shreveport. Her work in Dr. Tibbetts lab involved utilizing a murine gammaherpesvirus, MHV68, as an in vivo model to characterize the role of developing B cells in the maintenance of viral latency. She obtained her Ph.D. in virology in...

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    Davis M.D., Randall, Senior Scientist

    A graduate of Boston University in Boston, Massachusetts, Dr. Davis completed medical school at the University of Alabama School of Medicine (UASOM), where he also served his internship, residency, and the ABIM academic subspecialty research fellowship clinical investigator pathway in Hematology/Oncology. He is Professor of Medicine, Microbiology, and Biochemistry and Molecular Genetics in the division of Hematology/Oncology. He is board certified in Hematology.

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    Deshane Ph.D., Jessy, Scientist

    Jessy Deshane received her PhD in Biochemistry and Molecular Genetics from University of Alabama at Birmingham under the mentorship of Dr. Anupam Agarwal. After completing her post-doctoral training in Immunology with Dr. David Chaplin, in Department of Microbiology, she joined the faculty of the Division of Pulmonary, Allergy, and Critical Care Medicine in the Department of Medicine in 2011 as an Assistant Professor.

    Dr. Deshane is committed to an academic career combining basic and tr...

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    Elson III M.D., Charles, Senior Scientist

    Dr. Elson received his M.D. from Washington University in St. Louis, trained in Internal Medicine at New York Hospital/Cornell, then did his Gastroenterology fellowship at the University of Chicago.  After doing full-time research in immunology at N.I.H., he joined the Faculty of the Division of Gastroenterology at the Medical College of Virginia.  He moved to the University of Alabama at Birmingham to become Director of the Division of Gastroenterology and Hepatology,  and subsequently served a...

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    Frolov Ph.D., Ilya, Senior Scientist

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    Frolova Ph.D., Elena, Senior Scientist

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    Goepfert M.D., Paul, Senior Scientist

    Our laboratory concentrates on understanding the immune correlates of protection against HIV disease progression with a focus on cell medicated immune responses (CD4 and CD8 T cells). We are utilizing a variety of techniques in our laboratory to evaluate the quality of HIV-specific T cell responses observed in patients who represent the entire spectra of HIV disease. These assays include an in vitro HIV killing and an in vitro HIV viral suppression assay. These assays measure the actual clearanc...

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    Goldman M.D., Frederick, Senior Scientist

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    Hel Ph.D., Zdenek, Senior Scientist

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    Hu Ph.D., Hui, Scientist

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    Jilling M.D., Tamas, Scientist

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    Justement Ph.D., Louis, Senior Scientist

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    Kabarowski Ph.D., Janusz, Scientist

    Janusz H.S. Kabarowski received his B.Sc. degree in Biochemistry from University College London, UK. He was awarded a Ph.D. degree from the Leukaemia Research Fund centre at The Institute of Cancer Research (Chester Beatty Laboratories) in London in 1997. Dr. Kabarowski subsequently conducted postdoctoral research in the laboratory of Owen Witte at UCLA. Dr. Kabarowski joined the Department of Microbiology at UAB as an Assistant Professor in 2003 and has a secondary faculty appointment in the De...

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    Kappes Ph.D., John, Scientist

    John C. Kappes (b. 1957), Associate Professor of Medicine and Microbiology, completed his undergraduate studies in biology at Thomas More College (B.A. in Biology, 1981) and received his Ph.D. in Microbiology and Experimental Medicine from St. Thomas Institute in 1986. Dr. Kappes completed his postdoctoral fellowship studying the molecular pathogenesis of human immunodeficiency viruses and joined the UAB faculty in 1989.

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    Kearney Ph.D., John, Senior Scientist

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    Leon-Ruiz Ph.D., Beatriz, Associate Scientist

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    Liu, Xiaoguang, Scientist

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    Lund Ph.D., Frances, Senior Scientist

    Frances (Fran) Lund completed her undergraduate studies in Microbiology at the University of Notre Dame (B.S., cum laude, 1987). She performed her graduate work with Dr. Ronald B. Corley in the Department of Microbiology at Duke University. She obtained her Ph.D. in Immunology in 1992 and went on to a post-doctoral immunology fellowship in Dr. Maureen Howard’s group at DNAX Research Institute in Palo Alto, CA. In 1997 she moved to the Trudeau Institute, a basic biomedical infectious disease rese...

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    Luo M.D., Guangxiang, Senior Scientist

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    Maynard Ph.D., Craig, Associate Scientist

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    Mountz M.D., Ph.D., John, Senior Scientist

    Dr. Mountz is a Professor of Medicine and Director of the UAB Recombinant Inbred Strain Facility. Dr. Mountz is the Co-Director of the UAB Bone Center, the UAB Center for Aging, Basic Biology Component, and is a Physician at the Birmingham Veterans Administration Medical Center. Dr. Mountz is the recipient of the J. W. & Virginia Goodwin-Warren D. Blackburn, Jr. Research Chair in Rheumatology (2002) and recipient of the Max Cooper Award for Excellence in Research (2003). Dr. Mountz was designate...

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    Nahm M.D., Moon, Senior Scientist

    Moon H. Nahm, Professor of Department of Medicine, with secondary appointment in Microbiology, obtained both his BA degree (in 1970) and MD degree (in 1974) from Washington University in St. Louis MO. In 1980, he completed both Internal Medicine and Laboratory Medicine residency training in Pathology Department, as well as completing post-doctoral research training in Microbiology Department at Washington University in St. Louis MO. He was a faculty member at Washington University in St. Louis a...

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    Novak M.Sc., Ph.D., Jan, Senior Scientist

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    Randall Ph.D., Troy, Senior Scientist

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    Saad Ph.D., Jamil, Scientist

    Obtained his B.S degree in Chemistry at Birzeit University in Palestine (1996), M.S degree in Bioinorganic Chemistry at Bergen University in Norway (1998; advisor: Dr. Einar Sletten), and a Ph.D degree in Bioinorganic Chemistry at Emory University in Atlanta (2002; advisor: Dr. Luigi Marzilli). His M.S. and Ph.D studies focused on studying the interactions of cisplatin, a leading anticancer drug, with DNA by using Nuclear Magnetic Resonance (NMR) and other biophysical methods. Dr. Saad's postdoc...

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    Saag M.D., Michael, Senior Scientist

    I am Associate Dean for Global Health in the School of Medicine, Director of the UAB Center for AIDS Research and a Professor of Medicine in the Division of Infectious Diseases. I am also the principal investigator of the CFAR Network of Integrated Clinical Systems (CNICS), an NIAID-funded National Network of EMR-collected clinical data at 8 CFAR centers that are merged for the purposes of clinical research. I am the founding director of the UAB 1917 HIV Clinic, which has pioneered treatment pro...

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    Schroeder Jr, Harry, Senior Scientist

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    Shi, Lewis Zhichang, Scientist

    Lewis Shi received his MD in preventive medicine, MS in toxicology, and PhD in neurotoxicology. Upon graduation, he worked as a postdoctoral scholar at University of Wisconsin-Madison where he identified a novel role of the aryl hydrocarbon receptor (AhR) signaling in innate immune response against Listeria monocytogenes infection. He then joined St. Jude Children’s Research Hospital where he was among the first to show that the HIF-1a-glycolysis pathway functions as a metabolic checkpoint in re...

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    Smith M.D., Phillip, Senior Scientist

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    Tang Ph.D., Jianming, Senior Scientist

    As an immunologist by training, my ongoing research focuses on immunogenetic factors in several infectious diseases, especially HIV/AIDS.

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    Weaver M.D., Casey, Senior Scientist

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    Weinmann Ph.D., Amy, Senior Scientist

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    Xu Ph.D., Hui, Senior Scientist

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    Zajac Ph.D., Allan, Senior Scientist

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