Positions

Selected Publications

Academic Article

Year Title Altmetric
2017 Beyond cystic fibrosis transmembrane conductance regulator (CFTR) single channel kinetics: implications for therapeutic intervention.Journal of Physiology.  595:1015-1016. 2017
2016 Analysis of cystic fibrosis-associated P67L CFTR illustrates barriers to personalized therapeutics for orphan diseases.JCI insight.  1. 2016
2016 The Cystic Fibrosis Transmembrane Conductance Regulator Potentiator Ivacaftor Augments Mucociliary Clearance Abrogating Cystic Fibrosis Transmembrane Conductance Regulator Inhibition by Cigarette Smoke.American Journal of Respiratory Cell and Molecular Biology.  56:99-108. 2016
2016 Expression and purification of the alpha subunit of the epithelial sodium channel, ENaC.Protein Expression and Purification.  117:67-75. 2016
2015 Physical and functional interactions between a glioma cation channel and integrin-β1 require α-actinin.American Journal of Physiology - Cell Physiology.  309:C308-C319. 2015
2014 An aberrant leukotriene A4 hydrolase-proline-glycine-proline pathway in the pathogenesis of chronic obstructive pulmonary disease.American Journal of Respiratory and Critical Care Medicine.  190:51-61. 2014
2014 Cystic fibrosis transmembrane conductance regulator activation by roflumilast contributes to therapeutic benefit in chronic bronchitis.American Journal of Respiratory Cell and Molecular Biology.  50:549-558. 2014
2014 Erratum: Resveratrol Enhances Airway Surface Liquid Depth in Sinonasal Epithelium by Increasing Cystic Fibrosis Transmembrane Conductance Regulator Open Probability (PLoS ONE (2014) 9:1 (DOI:10.1371/annotation/d852ff1d-2824- 4f4d-80f2-9be7a42a5f25))PLoS ONE.  9. 2014
2014 Sinupret activates CFTR and TMEM16A-dependent transepithelial chloride transport and improves indicators of mucociliary clearance.PLoS ONE.  9:e104090. 2014
2013 Cigarette smoke induces systemic defects in cystic fibrosis transmembrane conductance regulator functionAmerican Journal of Respiratory and Critical Care Medicine.  188:1321-1330. 2013
2013 Cigarette smoke induces systemic defects in cystic fibrosis transmembrane conductance regulator function.American Journal of Respiratory and Critical Care Medicine.  188:1321-1330. 2013
2013 IL-8 inhibits cAMP-stimulated alveolar epithelial fluid transport via a GRK2/PI3K-dependent mechanism.Federation proceedings.  27:1095-1106. 2013
2013 Resveratrol enhances airway surface liquid depth in sinonasal epithelium by increasing cystic fibrosis transmembrane conductance regulator open probability.PLoS ONE.  8:e81589. 2013
2012 Glioma-specific cation conductance regulates migration and cell cycle progression.Journal of Biological Chemistry.  287:4053-4065. 2012
2011 Interaction of ASIC1 and ENaC subunits in human glioma cells and rat astrocytes.American Journal of Physiology - Cell Physiology.  300:C1246-C1259. 2011
2009 Mammalian target of rapamycin: MasTOR mediator of cellular changes in pathological states?Hypertension.  54:1221-1222. 2009
2009 Phosphatidylinositol 4,5-bisphosphate (PIP2) stimulates the electrogenic Na/HCO3 cotransporter NBCe1-A expressed in Xenopus oocytes.Proceedings of the National Academy of Sciences.  106:14150-14155. 2009
2006 Activation of gadolinium-sensitive ion channels in cardiomyocytes in early adaptive stages of volume overload-induced heart failure.Cardiovascular Research.  72:262-270. 2006
2006 Electrogenic Na/HCO3 cotransporter (NBCe1) variants expressed in Xenopus oocytes: functional comparison and roles of the amino and carboxy termini.Journal of General Physiology.  127:639-658. 2006
2006 Reactive species mediate inhibition of alveolar type II sodium transport during mycoplasma infection.American Journal of Respiratory and Critical Care Medicine.  173:334-344. 2006
2004 Regulation of amiloride-sensitive Na(+) transport by basal nitric oxide.American Journal of Respiratory Cell and Molecular Biology.  30:720-728. 2004
2002 Ablation of internalization signals in the carboxyl-terminal tail of the cystic fibrosis transmembrane conductance regulator enhances cell surface expression.Journal of Biological Chemistry.  277:49952-49957. 2002
1998 pH-dependent modulation of the cloned renal K+ channel, ROMKAJP - Renal Physiology.  275. 1998
1998 pH-dependent modulation of the cloned renal K+ channel, ROMK.American Journal of Physiology.  275:F972-F981. 1998
1998 Partially active channels produced by PKA site mutation of the cloned renal K+ channel, ROMK2 (kir1.2)AJP - Renal Physiology.  275. 1998
1998 Partially active channels produced by PKA site mutation of the cloned renal K+ channel, ROMK2 (kir1.2).American Journal of Physiology.  275:F415-F422. 1998
1997 A functional CFTR-NBF1 is required for ROMK2-CFTR interactionAJP - Renal Physiology.  273. 1997
1997 A functional CFTR-NBF1 is required for ROMK2-CFTR interaction.American Journal of Physiology.  273:F843-F848. 1997
1997 Diversity of channels generated by different combinations of epithelial sodium channel subunits.Journal of General Physiology.  109:681-692. 1997
1996 Molecular site for nucleotide binding on an ATP-sensitive renal K+channel (ROMK2)American Journal of Physiology.  271. 1996
1996 Molecular site for nucleotide binding on an ATP-sensitive renal K+ channel (ROMK2).American Journal of Physiology.  271:F275-F285. 1996
1996 Sensitivity of a renal K+ channel (ROMK2) to the inhibitory sulfonylurea compound glibenclamide is enhanced by coexpression with the ATP-binding cassette transporter cystic fibrosis transmembrane regulator.Proceedings of the National Academy of Sciences.  93:8083-8088. 1996
1995 Primary structure and functional expression of a cGMP-gated potassium channel.Proceedings of the National Academy of Sciences.  92:11711-11715. 1995
1995 Regulation of ATP-sensitive K+ channel by membrane-bound protein phosphatases in rat principal tubule cellAJP - Renal Physiology.  269. 1995
1995 Regulation of ATP-sensitive K+ channel by membrane-bound protein phosphatases in rat principal tubule cell.American Journal of Physiology.  269:F355-F362. 1995
1995 Role of Ca2+/CaMK II in Ca2+-induced K+ channel inhibition in rat CCD principal cellAJP - Renal Physiology.  268. 1995
1995 Role of Ca2+/CaMK II in Ca(2+)-induced K+ channel inhibition in rat CCD principal cell.American Journal of Physiology.  268:F211-F219. 1995
1994 Na-K-Cl cotransport in villus and crypt cells from rat duodenumAmerican Journal of Physiology.  267. 1994
1994 Na-K-Cl cotransport in villus and crypt cells from rat duodenumAJP - Gastrointestinal and Liver Physiology.  267. 1994
1994 Na-K-Cl cotransport in villus and crypt cells from rat duodenum.American Journal of Physiology.  267:G1004-G1011. 1994
1994 Regulation of ROMK1 K+ channel activity involves phosphorylation processes.Proceedings of the National Academy of Sciences.  91:8077-8081. 1994
1994 A novel approach allows identification of K channels in the lateral membrane of rat CCDAJP - Renal Physiology.  266. 1994
1994 Properties and regulation of basolateral K+ channels in rat duodenal crypts.Journal of Physiology.  477 ( Pt 3):381-392. 1994
1994 A novel approach allows identification of K channels in the lateral membrane of rat CCD.American Journal of Physiology.  266:F813-F822. 1994
1994 Aldosterone-induced apical Na+ and K+ conductances are located predominantly in surface cells in rat distal colonAmerican Journal of Physiology.  266. 1994
1994 A novel approach allows identification of K channels in the lateral membrane of rat CCDAmerican Journal of Physiology.  266. 1994
1994 Aldosterone-induced apical Na+ and K+ conductances are located predominantly in surface cells in rat distal colonAmerican Journal of Physiology.  266. 1994
1994 Aldosterone-induced apical Na+ and K+ conductances are located predominantly in surface cells in rat distal colon.American Journal of Physiology.  266:G71-G82. 1994
1994 Potassium channels in colonic crypts.Lancet.  343:23-25. 1994
1992 A Cl- conductance sensitive to external pH in the apical membrane of rat duodenal enterocytes.Journal of Physiology.  456:519-528. 1992

Education And Training

  • Doctor of Philosophy in Cell Physiology, The University of Manchester
  • Full Name

  • Carmel McNicholas-Bevensee
  • Blazerid

  • cbevense