Positions

Selected Publications

Academic Article

Year Title Altmetric
2021 IgA Nephropathy: An Interesting Autoimmune Kidney Disease: IgA NephropathyAmerican Journal of the Medical Sciences.  361:176-194. 2021
2020 Genome-wide association study for time to failure of kidney transplants from African American deceased donorsClinical Transplantation.  34. 2020
2020 Role of Epstein-Barr Virus in Pathogenesis and Racial Distribution of IgA NephropathyFrontiers in Immunology.  11. 2020
2020 Redefining the Influence of Ethnicity on Simultaneous Kidney and Pancreas Transplantation Outcomes: A 15-year Single-center ExperienceAnnals of Surgery.  271:177-183. 2020
2019 CureGN Study Rationale, Design, and Methods: Establishing a Large Prospective Observational Study of Glomerular DiseaseAmerican Journal of Kidney Diseases.  73:218-229. 2019
2019 The emerging role of complement proteins as a target for therapy of IgA nephropathyFrontiers in Immunology.  10. 2019
2018 Assay for galactose-deficient IgA1 enables mechanistic studies with primary cells from IgA nephropathy patients 2018
2018 Apolipoprotein L1 and Chronic Kidney Disease Risk in Young Potential Living Kidney DonorsAnnals of Surgery.  267:1161-1168. 2018
2017 Effect of Replacing Race With Apolipoprotein L1 Genotype in Calculation of Kidney Donor Risk IndexAmerican Journal of Transplantation.  17:1540-1548. 2017
2016 The origin and activities of IgA1-containing immune complexes in IGA nephropathyFrontiers in Immunology.  7. 2016
2016 Galactose-Deficient IgA1 as a Candidate Urinary Polypeptide Marker of IgA Nephropathy?Disease Markers.  2016. 2016
2016 Toward Noninvasive Diagnosis of IgA Nephropathy: A Pilot Urinary Metabolomic and Proteomic StudyDisease Markers.  2016. 2016
2015 Apolipoprotein L1 gene variants in deceased organ donors are associated with renal allograft failureAmerican Journal of Transplantation.  15:1615-1622. 2015
2014 Immune profile of IgA-dominant diffuse proliferative glomerulonephritisClinical Kidney Journal.  7:479-483. 2014
2014 End-stage renal disease in African Americans with lupus nephritis is associated with APOL1Arthritis and Rheumatology.  66:390-396. 2014
2013 Biomarkers in IgA nephropathy: Relationship to pathogenetic hitsExpert Opinion on Medical Diagnostics.  7:615-627. 2013
2013 Pathogenesis of immunoglobulin A nephropathyCurrent Opinion in Nephrology and Hypertension.  22:287-294. 2013
2013 IgA nephropathy: Molecular mechanisms of the diseaseAnnual Review of Pathology: Mechanisms of Disease.  8:217-240. 2013
2012 Association of IgG co-deposition with serum levels of galactose-deficient IgA1 in pediatric IgA nephropathy.Clinical Nephrology.  78:465-469. 2012
2012 Association of IgG co-deposition with serum levels of galactose-deficient IgA1 in pediatric IgA nephropathyClinical Nephrology.  78:465-469. 2012
2011 Aberrant glycosylation of iga1 and anti-glycan antibodies in iga nephropathy: Role of mucosal immune system 2011
2011 Oxidative stress and galactose-deficient IgA1 as markers of progression in IgA nephropathyClinical Journal of the American Society of Nephrology.  6:1903-1911. 2011
2010 Galactose-deficient IgA1 in African Americans with IgA nephropathy: Serum levels and heritabilityClinical Journal of the American Society of Nephrology.  5:2069-2074. 2010
2010 Recognition of galactose-deficient O-glycans in the hinge region of IgA1 by N-acetylgalactosamine-specific snail lectins: A comparative binding study.Biochemistry.  49:5671-5682. 2010
2010 Familial IgA nephropathy in southeastern Kentucky.Clinical Nephrology.  73:115-121. 2010
2009 Risk factors and impact of recurrent lupus nephritis in patients with systemic lupus erythematosus undergoing renal transplantation: Data from a single US institutionArthritis and Rheumatism.  60:2757-2766. 2009
2009 Secondary listing for deceased-donor kidney transplantation does not increase likelihood of engraftment at a large transplant center: Brief communicationAmerican Journal of Transplantation.  9:1671-1673. 2009
2009 Isolated central nervous system posttransplant lymphoproliferative disorder treated with high-dose intravenous methotrexateAmerican Journal of Transplantation.  9:1243-1248. 2009
2007 Electrophoretic methods for analysis of urinary polypeptides in lgA-associated renal diseasesELECTROPHORESIS.  28:4469-4483. 2007
2007 Analysis of O-glycan heterogeneity in IgA1 myeloma proteins by Fourier transform ion cyclotron resonance mass spectrometry: Implications for IgA nephropathy 2007
2007 IgA nephropathy and henoch-schoenlein purpura nephritis: Aberrant glycosylation of IgA1, formation of IgA1-containing immune complexes, and activation of mesangial cellsContributions to Nephrology.  157:134-138. 2007
2007 IgA nephropathy: A clinical overviewContributions to Nephrology.  157:19-26. 2007
2007 IgA nephropathy: Characterization of IgG antibodies specific for galactose-deficient IgA1Contributions to Nephrology.  157:129-133. 2007
2007 IgA nephropathy: Current views of immune complex formationContributions to Nephrology.  157:56-63. 2007
2006 Brief communication: Glomerulonephritis in patients with hepatitis C cirrhosis undergoing liver transplantationAnnals of Internal Medicine.  144:735-741. 2006
2006 Clinical trial to evaluate omega-3 fatty acids and alternate day prednisone in patients with IgA nephropathy: report from the Southwest Pediatric Nephrology Study Group.Clinical Journal of the American Society of Nephrology.  1:467-474. 2006
2004 IgA nephropathy: An updateCurrent Opinion in Nephrology and Hypertension.  13:171-179. 2004
2004 Incidence of hip osteonecrosis among renal transplantation recipients: A prospective studyClinical Radiology.  59:431-438. 2004
2000 Focal posttransplantation lymphoproliferative disorder at the renal allograft hilumAmerican Journal of Roentgenology.  175:1417-1422. 2000
2000 IgA1 glycosylation and the pathogenesis of IgA nephropathyAmerican Journal of Kidney Diseases.  35:551-554. 2000
1999 Parathyroid hormone-regulated production of stem cell factor in human osteoblasts and osteoblast-like cellsBiochemical and Biophysical Research Communications.  255:778-784. 1999
1999 Progress in the pathogenesis of IgA nephropathy. 1999
1999 Treatment of immunoglobulin A nephropathyAnnales de Medecine Interne.  150:127-136. 1999
1997 Human peritoneal B-1 cells and the influence of continuous ambulatory peritoneal dialysis on peritoneal and peripheral blood mononuclear cell (PBMC) composition and immunoglobulin levelsClinical and Experimental Immunology.  109:356-361. 1997
1997 The impact of renal transplantation on survival in hepatitis C- positive end-stage renal disease patientsAmerican Journal of Kidney Diseases.  29:608-614. 1997
1996 Benefits of continued cyclosporine through an indigent drug programAmerican Journal of Kidney Diseases.  28:572-577. 1996
1996 Dilemmas in renal transplantation: When the clinical course and histological findings differAmerican Journal of Kidney Diseases.  27:435-440. 1996
1995 IgA nephropathy: A disease of incomplete IgA 1 glycosylation?Advances in Experimental Medicine and Biology.  376:221-222. 1995
1995 Intraperitoneal administration of tetanus toxoid elicits a specific responses of antibody-secreting cells in the peritoneal cavityAdvances in Experimental Medicine and Biology.  371:103-106. 1995
1995 Progress in Renal Transplantation a Single Center Study of 3359 Patients over 25 YearsAnnals of Surgery.  221:446-458. 1995
1994 Intraperitoneal immunization of human subjects with tetanus toxoid induces specific antibody-secreting cells in the peritoneal cavity and in the circulation, but fails to elicit a secretory IgA responseClinical and Experimental Immunology.  96:356-363. 1994
1994 Posttransplant Erythrocytosis: An Enigma RevisitedAmerican Journal of Kidney Diseases.  24:1-11. 1994
1993 Alternate-day prednisone therapy in IgA nephropathy. Preliminary analysis of a prospective, randomized, controlled trial.Contributions to Nephrology.  104:198-206. 1993
1993 Defective galactosylation and clearance of IgA1 molecules as a possible etiopathogenic factor in IgA nephropathy.Contributions to Nephrology.  104:172-182. 1993
1993 Experience with mycophenolate mofetil (RS61443) in renal transplantation at a single centerAnnals of Surgery.  217:476-484. 1993
1993 Immunoglobulin A-Fibronectin Aggregate Levels in Children and Adults With Immunoglobulin A NephropathyAmerican Journal of Kidney Diseases.  22:1-4. 1993
1993 Metabolic bone disease in renal transplant recipientsEndocrinologist.  3:415-424. 1993
1993 ReplyAmerican Journal of Kidney Diseases.  21:344. 1993
1993 Tapering or Discontinuing Cyclosporine for Financial Reasons—A Single-Center ExperienceAmerican Journal of Kidney Diseases.  21:9-15. 1993
1992 Benefits of quadruple immunosuppressive therapy in recipients of living related donor kidneys: A review of 855 operationsAnnals of Surgery.  215:606-617. 1992
1992 Cytokine-Induced Immunoglobulin Production in Primary IgA NephropathyAmerican Journal of Kidney Diseases.  20:611-617. 1992
1992 Familial IgA Nephropathy Associated With Bilateral Sensorineural DeafnessAmerican Journal of Kidney Diseases.  19:592-596. 1992
1992 IgA-containing immune complexes after challenge with food antigens in patients with IgA nephropathyClinical and Experimental Immunology.  89:315-320. 1992
1992 Musculoskeletal Complications After Renal Transplantation: Pathogenesis and TreatmentAmerican Journal of Kidney Diseases.  19:99-120. 1992
1992 ReplyAmerican Journal of Kidney Diseases.  20:531. 1992
1991 Analysis of 22 years experience in living-related transplantation at the University of Alabama in Birmingham.Clinical Transplants.  179-191. 1991
1991 C4A deficiency and poor prognosis in patients with IgA nephropathyClinical Nephrology.  36:1-5. 1991
1991 Effects of enalapril on erythrocytosis after renal transplantationAnnals of Internal Medicine.  115:954-955. 1991
1991 Epstein-Barr virus Transformation of B Lymphocytes From IgA Nephropathy Patients and First-Degree Relatives Results in Increased Immunoglobulin Synthesis not Restricted to IgAAmerican Journal of Kidney Diseases.  17:55-61. 1991
1991 Macroscopic Hematuria and Proteinuria Preceding Renal IgA Deposition in Patients With IgA NephropathyAmerican Journal of Kidney Diseases.  17:472-479. 1991
1991 Role for specific complement phenotypes and deficiencies in the clinical expression of IgA nephropathyAmerican Journal of the Medical Sciences.  301:115-123. 1991
1991 Selective Elevation of Monomeric IgA1 in IgA Nephropathy Patients With Normal Renal FunctionAmerican Journal of Kidney Diseases.  18:313-319. 1991
1990 C4B Deficiency in Two Siblings With IgA NephropathyAmerican Journal of Kidney Diseases.  15:66-71. 1990
1990 Cyclosporine-induced changes in glomerular filtration rate and urea excretionAmerican Journal of Medicine.  88:497-502. 1990
1990 Cyclosporine-induced changes in glomerular filtration rate and urea excretionAmerican Journal of Medicine.  88:497-502. 1990
1990 Donor antigen-specific immunosuppression in cadaveric and living-related donor kidney allograft recipients.Clinical Transplants.  289-300. 1990
1990 J chain disease: A novel form of plasma cell dyscrasiaAmerican Journal of Medicine.  88:411-416. 1990
1988 A Comparison of OKT3 Monoclonal Antibody and Corticosteroids in the Treatment of Acute Renal Allograft RejectionAmerican Journal of Kidney Diseases.  11:86-89. 1988
1988 Activation of Complement in IgA NephropathyAmerican Journal of Kidney Diseases.  12:437-442. 1988
1988 Familial Clustering and Immunogenetic Aspects of IgA NephropathyAmerican Journal of Kidney Diseases.  12:366-370. 1988
1988 IgA nephropathy, the most common glomerulonephritis worldwide. A neglected disease in the United States?American Journal of Medicine.  84:129-132. 1988
1988 On the mechanism by which chloride corrects metabolic alkalosis in manAmerican Journal of Medicine.  84:449-458. 1988
1987 Morphologic and immunohistochemical observations in granulomatous glomerulonephritisAmerican Journal of Pathology.  126:581-591. 1987
1987 A major gene model for the familial aggregation of plasma IgA concentration 1987
1987 Aberrant synthesis of antibodies directed at the Fab fragment of IgA in patients with IgA nephropathiesClinical immunology and immunopathology.  45:208-213. 1987
1987 Antibodies directed at Fab of IgA in the sera of normal individuals and IgA nephropathy patients.Advances in Experimental Medicine and Biology.  216 B:1537-1544. 1987
1987 Complement phenotypes (C3 and C4) in IgA nephropathy.Advances in Experimental Medicine and Biology.  216 B:1569-1575. 1987
1987 Detection of food antigen-specific IgA immune complexes in human sera.Advances in Experimental Medicine and Biology.  216 A:813-820. 1987
1987 Fatal rhizopus infections in hemodialysis patients receiving deferoxamineAnnals of Internal Medicine.  107:678-679. 1987
1987 Immunological studies of IgA nephropathy: familial and racial aspects.Advances in Experimental Medicine and Biology.  216 B:1489-1498. 1987
1987 Influence of race on renal allograft survival in the pre- and postcyclosporine era.Clinical Transplants.  217-233. 1987
1987 Oxalosis in Bone Causing a Radiographical Mimicry of Renal OsteodystrophyAmerican Journal of Kidney Diseases.  9:436-440. 1987
1987 Regionalization in hereditary IgA nephropathyAmerican Journal of Human Genetics.  41:36-50. 1987
1987 Striking Elevation of Serum IgA, IgA-Containing Immune Complexes, and IgA Rheumatoid Factor in Clinically Silent Dermatitis HerpetiformisAmerican Journal of Kidney Diseases.  10:378-384. 1987
1986 Aluminum-related bone disease in mild and advanced renal failure: Evidence for high prevalence and morbidity and studies on etiology and diagnosisAmerican Journal of Nephrology.  6:275-283. 1986
1985 Focal Sclerosis of Hypertrophied Glomeruli in Solitary Functioning Kidneys of HumansAmerican Journal of Kidney Diseases.  5:226-232. 1985
1984 IgA Nephropathy: Presentation, Clinical Course, and Prognosis in Children and AdultsAmerican Journal of Kidney Diseases.  4:192-200. 1984
1984 Increased frequency of C3 fast alleles in IgA nephropathyDisease Markers.  2:419-428. 1984
1983 Serum complement proteins in IgA nephropathyClinical Nephrology.  20:251-258. 1983

Chapter

Year Title Altmetric
2016 Heterogeneity of aberrant O-glycosylation of IgA1 in IgA nephropathy.  53-68. 2016
2015 IgA Nephropathy and Related Diseases.  2023-2038. 2015
2009 Clinicopathologic findings.  83-106. 2009

Investigator On

  • Private Grant  awarded by NATERA, INC. 2020 - 2030
  • Private Grant  awarded by VITAERIS, INC. 2020 - 2028
  • Private Grant  awarded by CALLIDITAS THERAPEUTICS AB 2019 - 2026
  • Genetic, Environmental & Histologic Basis for Kidney Disease Risk among Persons Living with HIV  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2020 - 2025
  • Pathogenic Autoantibodies with Specificity for Aberrant Glycoproteins: Assessment of a Therapeutic Target in an Autoimmune Disease  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS 2020 - 2025
  • Private Grant  awarded by VISTERRA, INC 2020 - 2024
  • Molecular Basis of Pathogenicity of IgA1-Containing Immune Complexes  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2019 - 2024
  • Private Grant  awarded by RETROPHIN, INC. 2019 - 2024
  • Private Grant  awarded by VELOXIS PHARMACEUTICALS A/S 2019 - 2023
  • Private Grant  awarded by MALLINCKRODT, INC. 2021 - 2022
  • Private Grant  awarded by MALLINCKRODT, INC. 2017 - 2022
  • Effects of Inhibiting Early Inflammation in Kidney Transplant Patients  awarded by ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI 2019 - 2021
  • Abnormal STAT3 Signaling and Aberrant O-Glycosylation of IgA1 in IgA Nephropathy  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2015 - 2021
  • Novel Therapies to Modulate the Inflammatory Alloresponse in Renal Grafts  awarded by University of California, San Francisco 2019 - 2021
  • Cure GN 2.0 - UNC-PCC  awarded by University of North Carolina 2020 - 2021
  • Genetics of IgA Nephropathy by Integrative Network-Based Association Studies  awarded by Columbia University 2015 - 2021
  • Private Grant  awarded by ALEXION PHARMACEUTICALS, INC. 2018 - 2020
  • Elucidating IgA Nephropathy Through Genetic Studies of IgA1 Glycosylation  awarded by Columbia University 2014 - 2020
  • Private Grant  awarded by CSL BEHRING, LLC 2020
  • Private Grant  awarded by CSL BEHRING, LLC 2017 - 2020
  • Analytical Tools for the Analysis of Clustered O-Glycans in Clinical Samples  awarded by National Institute of General Medical Sciences/NIH/DHHS 2016 - 2020
  • Genetic, Environmental & Histologic Basis for Kidney Disease Risk among Persons Living with HIV  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2018 - 2019
  • Effects of Inhibiting Early Inflammation in Kidney Transplant Patients - Equipment  awarded by Mount Sinai School of Medicine ^ 2015 - 2019
  • Novel Therapies to Modulate the Inflammatory Alloresponse in Renal Grafts  awarded by University of California, San Francisco 2014 - 2019
  • APOL1 Long-Term Kidney Transplantation Outcomes Network (APOLLO) Clinical Center  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2019
  • UAB Center for AIDS Research  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS 2014 - 2019
  • Private Grant  awarded by QUARK PHARMACEUTICALS, INC. 2015 - 2019
  • Molecular Basis of Pathogenicity of IgA1-containing Immune Complexes  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2012 - 2019
  • Aptamers-Based Arrays for Detection of Pathogenic IgA 1 O-Glycoforms in IgA Nephropathy  awarded by Columbia University 2016 - 2018
  • IgA Nephropathy: Interventions with Generation of Nephritogenic Immune Complexes  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2014 - 2018
  • Private Grant  awarded by ALEXION PHARMACEUTICALS, INC. 2014 - 2017
  • Preserving Renal Function & Protective Immunity via Anti-LFA-1-Based CNI Avoidance  awarded by Emory University 2009 - 2016
  • Analytical Tools for the Analysis of Clustered O-Glycans in Clinical Samples  awarded by National Institute of General Medical Sciences/NIH/DHHS 2011 - 2016
  • Private Grant  awarded by ANTHERA PHARMACEUTICALS, INC 2015 - 2016
  • Private Grant  awarded by Pfizer Pharmaceuticals 2013 - 2015
  • Elucidating IgA Nephropathy Through Genetic Studies of IgA1 Glycosylation  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2009 - 2014
  • New Animal Model for Studies of Mucosal Immunity and IgA Nephropathy  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2010 - 2013
  • Education And Training

  • Doctor of Medicine, Washington University/St. Louis 1975
  • University of Kentucky/Chandler Hospital, Internship 1976
  • University of Kentucky/Chandler Hospital, Residency 1978
  • University of Kentucky/Chandler Hospital, Postdoctoral Fellowship 1980
  • Full Name

  • Bruce Julian