Positions

Selected Publications

Academic Article

Year Title Altmetric
2019 CureGN Study Rationale, Design, and Methods: Establishing a Large Prospective Observational Study of Glomerular Disease.American Journal of Kidney Diseases.  73:218-229. 2019
2018 Population Health, Ethnicity, and Rate of Living Donor Kidney Transplantation.Transplantation.  102:2080-2087. 2018
2018 Clinical Characteristics and Treatment Patterns of Children and Adults With IgA Nephropathy or IgA Vasculitis: Findings From the CureGN Study.Kidney International Reports.  3:1373-1384. 2018
2018 Aberrant Glycosylation of the IgA1 Molecule in IgA Nephropathy.Seminars in Nephrology.  38:461-476. 2018
2018 Genome-wide association studies suggest that APOL1-environment interactions more likely trigger kidney disease in African Americans with nondiabetic nephropathy than strong APOL1-second gene interactions.Kidney International.  94:599-607. 2018
2018 Apolipoprotein L1 and Chronic Kidney Disease Risk in Young Potential Living Kidney Donors.Annals of Surgery.  267:1161-1168. 2018
2018 Redefining the Influence of Ethnicity on Simultaneous Kidney and Pancreas Transplantation Outcomes: A 15-Year Single-Center Experience.Annals of Surgery2018
2018 Evaluation of Potential Living Kidney Donors in the APOL1 Era.Journal of the American Society of Nephrology.  29:1079-1081. 2018
2018 Life Expectancy for Patients From the Southeastern United States With IgA Nephropathy.Kidney International Reports.  3:99-104. 2018
2018 Secondary IgA nephropathy.Kidney International.  94:674-681. 2018
2018 Serum galactose-deficient-IgA1 and IgG autoantibodies correlate in patients with IgA nephropathy.PLoS ONE.  13:e0190967. 2018
2017 Noninvasive diagnosis of chronic kidney diseases using urinary proteome analysis.Nephrology Dialysis Transplantation.  32:2079-2089. 2017
2017 Influence of Kidney Transplant Status on Warfarin Dose, Anticoagulation Control, and Risk of Hemorrhage.Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy.  37:1366-1373. 2017
2017 Inhibition of STAT3 Signaling Reduces IgA1 Autoantigen Production in IgA Nephropathy.Kidney International Reports.  2:1194-1207. 2017
2017 Effect of Replacing Race With Apolipoprotein L1 Genotype in Calculation of Kidney Donor Risk Index.American Journal of Transplantation.  17:1540-1548. 2017
2017 Prognostic Value of Serum Biomarkers of Autoimmunity for Recurrence of IgA Nephropathy after Kidney Transplantation.Journal of the American Society of Nephrology.  28:1943-1950. 2017
2017 A Randomized, Controlled Trial of Rituximab in IgA Nephropathy with Proteinuria and Renal Dysfunction.Journal of the American Society of Nephrology.  28:1306-1313. 2017
2017 GWAS for serum galactose-deficient IgA1 implicates critical genes of the O-glycosylation pathway.PLoS Genetics.  13:e1006609. 2017
2017 Apolipoprotein L1 Gene Effects on Kidney Transplantation.Seminars in Nephrology.  37:530-537. 2017
2017 Evidence from the Oxford Classification cohort supports the clinical value of subclassification of focal segmental glomerulosclerosis in IgA nephropathy.Kidney International.  91:235-243. 2017
2017 Serial Galactose-Deficient IgA1 Levels in Children with IgA Nephropathy and Healthy Controls.International Journal of Nephrology.  2017:8210641. 2017
2016 Somatic Mutations Modulate Autoantibodies against Galactose-Deficient IgA1 in IgA Nephropathy.Journal of the American Society of Nephrology.  27:3278-3284. 2016
2016 APOL1 Genotype and Kidney Transplantation Outcomes From Deceased African American Donors.Transplantation.  100:194-202. 2016
2016 Deceased-Donor Apolipoprotein L1 Renal-Risk Variants Have Minimal Effects on Liver Transplant Outcomes.PLoS ONE.  11:e0152775. 2016
2016 Galactose-Deficient IgA1 as a Candidate Urinary Polypeptide Marker of IgA Nephropathy?Disease Markers.  2016:7806438. 2016
2016 The MEST score provides earlier risk prediction in lgA nephropathy.Kidney International.  89:167-175. 2016
2016 The Origin and Activities of IgA1-Containing Immune Complexes in IgA Nephropathy.Frontiers in Immunology.  7:117. 2016
2016 Toward Noninvasive Diagnosis of IgA Nephropathy: A Pilot Urinary Metabolomic and Proteomic Study.Disease Markers.  2016:3650909. 2016
2015 Deceased donor multidrug resistance protein 1 and caveolin 1 gene variants may influence allograft survival in kidney transplantation.Kidney International.  88:584-592. 2015
2015 Current Understanding of the Role of Complement in IgA Nephropathy.Journal of the American Society of Nephrology.  26:1503-1512. 2015
2015 Apolipoprotein L1 gene variants in deceased organ donors are associated with renal allograft failure.American Journal of Transplantation.  15:1615-1622. 2015
2015 New Insights into the Pathogenesis of IgA Nephropathy.Kidney Diseases.  1:8-18. 2015
2015 Should kidney donors be genotyped for APOL1 risk alleles?Kidney International.  87:671-673. 2015
2015 N-acetylgalactosaminide α2,6-sialyltransferase II is a candidate enzyme for sialylation of galactose-deficient IgA1, the key autoantigen in IgA nephropathy.Nephrology Dialysis Transplantation.  30:234-238. 2015
2014 Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens.Nature Genetics.  46:1187-1196. 2014
2014 Immune profile of IgA-dominant diffuse proliferative glomerulonephritis.Clinical Kidney Journal.  7:479-483. 2014
2014 Cytokines alter IgA1 O-glycosylation by dysregulating C1GalT1 and ST6GalNAc-II enzymes.Journal of Biological Chemistry.  289:5330-5339. 2014
2014 End-stage renal disease in African Americans with lupus nephritis is associated with APOL1.Arthritis and Rheumatology.  66:390-396. 2014
2014 A panel of serum biomarkers differentiates IgA nephropathy from other renal diseases.PLoS ONE.  9:e98081. 2014
2014 Cellular signaling and production of galactose-deficient IgA1 in IgA nephropathy, an autoimmune disease.Journal of Immunology Research.  2014:197548. 2014
2014 Enzymatic sialylation of IgA1 O-glycans: implications for studies of IgA nephropathy.PLoS ONE.  9:e99026. 2014
2013 Biomarkers in IgA nephropathy: relationship to pathogenetic hits.Expert Opinion on Medical Diagnostics.  7:615-627. 2013
2013 IgA nephropathy.New England Journal of Medicine.  368:2402-2414. 2013
2013 Pathogenesis of immunoglobulin A nephropathy.Current Opinion in Nephrology and Hypertension.  22:287-294. 2013
2013 IgA nephropathy: molecular mechanisms of the disease.Annual Review of Pathology: Mechanisms of Disease.  8:217-240. 2013
2012 Association of IgG co-deposition with serum levels of galactose-deficient IgA1 in pediatric IgA nephropathyClinical Nephrology.  78:465-469. 2012
2012 Association of IgG co-deposition with serum levels of galactose-deficient IgA1 in pediatric IgA nephropathy.Clinical Nephrology.  78:465-469. 2012
2012 The IgA1 immune complex-mediated activation of the MAPK/ERK kinase pathway in mesangial cells is associated with glomerular damage in IgA nephropathy.Kidney International.  82:1284-1296. 2012
2012 Autoantibodies targeting galactose-deficient IgA1 associate with progression of IgA nephropathy.Journal of the American Society of Nephrology.  23:1579-1587. 2012
2012 Reply to "genetic determinants of mycophenolate-related anemia and leukopenia after transplantation"Transplantation.  93. 2012
2012 Glycosylation of IgA1 and pathogenesis of IgA nephropathy.Springer Seminars in Immunopathology.  34:365-382. 2012
2012 Naturally occurring structural isomers in serum IgA1 o-glycosylation.Journal of Proteome Research.  11:692-702. 2012
2012 Erratum: Mice overexpressing BAFF develop a commensal flora-dependent, IgA-associated nephropathy (Journal of Clinical Investigation (2011) 121, 10 (3991-4002) DOI: 10.1172/JCI45563)Journal of Clinical Investigation.  122:778. 2012
2012 Geographic differences in genetic susceptibility to IgA nephropathy: GWAS replication study and geospatial risk analysis.PLoS Genetics.  8:e1002765. 2012
2012 In vitro-generated immune complexes containing galactose-deficient IgA1 stimulate proliferation of mesangial cells.Results in Immunology.  2:166-172. 2012
2012 Serum galactose-deficient IgA1 level is not associated with proteinuria in children with IgA nephropathy.International Journal of Nephrology.  2012:315467. 2012
2011 Membrane-assisted online renaturation for automated microfluidic lectin blotting.Journal of the American Chemical Society.  133:19610-19613. 2011
2011 Sugars and alcohol: IgA-associated renal diseases in alcoholic cirrhosis.Kidney International.  80:1252-1254. 2011
2011 APOL1 variants increase risk for FSGS and HIVAN but not IgA nephropathy.Journal of the American Society of Nephrology.  22:1991-1996. 2011
2011 IgA1 immune complexes from pediatric patients with IgA nephropathy activate cultured human mesangial cells.Nephrology Dialysis Transplantation.  26:3451-3457. 2011
2011 Mice overexpressing BAFF develop a commensal flora-dependent, IgA-associated nephropathy.Journal of Clinical Investigation.  121:3991-4002. 2011
2011 The pathophysiology of IgA nephropathy.Journal of the American Society of Nephrology.  22:1795-1803. 2011
2011 Oxidative stress and galactose-deficient IgA1 as markers of progression in IgA nephropathy.Clinical Journal of the American Society of Nephrology.  6:1903-1911. 2011
2011 Validation of the Oxford classification of IgA nephropathy.Kidney International.  80:310-317. 2011
2011 Aberrant glycosylation of IgA1 is inherited in both pediatric IgA nephropathy and Henoch-Schönlein purpura nephritis.Kidney International.  80:79-87. 2011
2011 Genome-wide association study identifies susceptibility loci for IgA nephropathy.Nature Genetics.  43:321-327. 2011
2011 Genetic determinants of mycophenolate-related anemia and leukopenia after transplantation.Transplantation.  91:309-316. 2011
2011 Novel polymorphisms associated with tacrolimus trough concentrations: results from a multicenter kidney transplant consortium.Transplantation.  91:300-308. 2011
2011 Aberrant glycosylation of IgA1 and anti-glycan antibodies in IgA nephropathy: role of mucosal immune system.Advances in Otorhinolaryngology.  72:60-63. 2011
2010 Clustered O-glycans of IgA1: defining macro- and microheterogeneity by use of electron capture/transfer dissociation.Molecular and Cellular Proteomics.  9:2545-2557. 2010
2010 Galactose-deficient IgA1 in African Americans with IgA nephropathy: serum levels and heritability.Clinical Journal of the American Society of Nephrology.  5:2069-2074. 2010
2010 Genetic studies of IgA nephropathy: past, present, and future.Pediatric Nephrology.  25:2257-2268. 2010
2010 Naturally occurring human urinary peptides for use in diagnosis of chronic kidney disease.Molecular and Cellular Proteomics.  9:2424-2437. 2010
2010 Recommendations for biomarker identification and qualification in clinical proteomics.Science Translational Medicine.  2:46ps42. 2010
2010 Recognition of galactose-deficient O-glycans in the hinge region of IgA1 by N-acetylgalactosamine-specific snail lectins: a comparative binding study.Biochemistry.  49:5671-5682. 2010
2010 Glomerulonephritis after hematopoietic cell transplantation: IgA nephropathy with increased excretion of galactose-deficient IgA1.Nephrology Dialysis Transplantation.  25:1708-1713. 2010
2010 The Oxford IgA nephropathy clinicopathological classification is valid for children as well as adults.Kidney International.  77:921-927. 2010
2010 Tissue distribution and biological activities of immune complexes are determined by their size and composition.Nephrology Dialysis Transplantation.  25:1007. 2010
2010 Familial IgA nephropathy in southeastern Kentucky.Clinical Nephrology.  73:115-121. 2010
2010 Familial IgA nephropathy in southeastern KentuckyClinical Nephrology.  73:115-121. 2010
2009 Risk factors and impact of recurrent lupus nephritis in patients with systemic lupus erythematosus undergoing renal transplantation: data from a single US institution.Arthritis and Rheumatism.  60:2757-2766. 2009
2009 The Oxford classification of IgA nephropathy: pathology definitions, correlations, and reproducibility.Kidney International.  76:546-556. 2009
2009 The Oxford classification of IgA nephropathy: rationale, clinicopathological correlations, and classification.Kidney International.  76:534-545. 2009
2009 Sources of Urinary Proteins and their Analysis by Urinary Proteomics for the Detection of Biomarkers of Disease.PROTEOMICS - Clinical Applications.  3:1029-1043. 2009
2009 Secondary listing for deceased-donor kidney transplantation does not increase likelihood of engraftment at a large transplant center.American Journal of Transplantation.  9:1671-1673. 2009
2009 Aberrantly glycosylated IgA1 in IgA nephropathy patients is recognized by IgG antibodies with restricted heterogeneity.Journal of Clinical Investigation.  119:1668-1677. 2009
2009 Isolated central nervous system posttransplant lymphoproliferative disorder treated with high-dose intravenous methotrexate.American Journal of Transplantation.  9:1243-1248. 2009
2009 Application of Proteomic Analysis to Renal Disease in the Clinic.PROTEOMICS - Clinical Applications.  3:1023-1028. 2009
2008 CE-MS analysis of the human urinary proteome for biomarker discovery and disease diagnostics.PROTEOMICS - Clinical Applications.  2:964. 2008
2008 Urinary proteomics in diabetes and CKD.Journal of the American Society of Nephrology.  19:1283-1290. 2008
2008 Systolic dysfunction portends increased mortality among those waiting for renal transplant.Journal of the American Society of Nephrology.  19:1191-1196. 2008
2008 Aberrant IgA1 glycosylation is inherited in familial and sporadic IgA nephropathy.Journal of the American Society of Nephrology.  19:1008-1014. 2008
2008 IgA1-secreting cell lines from patients with IgA nephropathy produce aberrantly glycosylated IgA1.Journal of Clinical Investigation.  118:629-639. 2008
2008 IgA glycosylation and IgA immune complexes in the pathogenesis of IgA nephropathy.Seminars in Nephrology.  28:78-87. 2008
2008 Role of aberrant glycosylation of IgA1 molecules in the pathogenesis of IgA nephropathy.Kidney and Blood Pressure Research.  31:29-37. 2008
2007 Electrophoretic methods for analysis of urinary polypeptides in IgA-associated renal diseases.ELECTROPHORESIS.  28:4469-4483. 2007
2007 Serum levels of galactose-deficient IgA in children with IgA nephropathy and Henoch-Schönlein purpura.Pediatric Nephrology.  22:2067-2072. 2007
2007 Analysis of O-glycan heterogeneity in IgA1 myeloma proteins by Fourier transform ion cyclotron resonance mass spectrometry: implications for IgA nephropathy.Fresenius' Journal of Analytical Chemistry.  389:1397-1407. 2007
2007 Urinary biomarkers of IgA nephropathy and other IgA-associated renal diseases.World Journal of Urology.  25:467-476. 2007
2007 High-resolution proteome/peptidome analysis of peptides and low-molecular-weight proteins in urine.PROTEOMICS - Clinical Applications.  1:792. 2007
2007 Patients with IgA nephropathy have increased serum galactose-deficient IgA1 levels.Kidney International.  71:1148-1154. 2007
2007 The genetics of IgA nephropathy.Nature Clinical Practice Nephrology.  3:325-338. 2007
2007 Identification and characterization of CMP-NeuAc:GalNAc-IgA1 alpha2,6-sialyltransferase in IgA1-producing cells.Journal of Molecular Biology.  369:69-78. 2007
2007 Reactivities of N-acetylgalactosamine-specific lectins with human IgA1 proteins.Molecular Immunology.  44:2598-2604. 2007
2007 Clinical proteomics: A need to define the field and to begin to set adequate standards.PROTEOMICS - Clinical Applications.  1:148-156. 2007
2007 IgA nephropathy and Henoch-Schoenlein purpura nephritis: aberrant glycosylation of IgA1, formation of IgA1-containing immune complexes, and activation of mesangial cells.Contributions to Nephrology.  157:134-138. 2007
2007 IgA nephropathy: a clinical overview.Contributions to Nephrology.  157:19-26. 2007
2007 IgA nephropathy: characterization of IgG antibodies specific for galactose-deficient IgA1.Contributions to Nephrology.  157:129-133. 2007
2007 IgA nephropathy: current views of immune complex formation.Contributions to Nephrology.  157:56-63. 2007
2006 IgA-containing immune complexes in the urine of IgA nephropathy patients.Nephrology Dialysis Transplantation.  21:2478-2484. 2006
2006 Brief communication: Glomerulonephritis in patients with hepatitis C cirrhosis undergoing liver transplantation.Annals of Internal Medicine.  144:735-741. 2006
2006 Clinical trial to evaluate omega-3 fatty acids and alternate day prednisone in patients with IgA nephropathy: report from the Southwest Pediatric Nephrology Study Group.Clinical Journal of the American Society of Nephrology.  1:467-474. 2006
2005 Recurrent IgA nephropathy after renal transplantation despite immunosuppressive regimens with mycophenolate mofetil.Nephrology Dialysis Transplantation.  20:1214-1221. 2005
2005 IgA1-containing immune complexes in IgA nephropathy differentially affect proliferation of mesangial cells.Kidney International.  67:504-513. 2005
2004 Incidence of hip osteonecrosis among renal transplantation recipients: a prospective study.Clinical Radiology.  59:431-438. 2004
2004 Angiotensin II receptor type 1 expression in erythroid progenitors: Implications for the pathogenesis of postrenal transplant erythrocytosis.Seminars in Nephrology.  24:120-130. 2004
2004 IgA nephropathy: an update.Current Opinion in Nephrology and Hypertension.  13:171-179. 2004
2003 Bone mineral density changes within six months of renal transplantationTransplantation.  75:49-54. 2003
2003 Bone mineral density changes within six months of renal transplantation.Transplantation.  75:49-54. 2003
2002 Interactions of human mesangial cells with IgA and IgA-containing immune complexes.Kidney International.  62:465-475. 2002
2001 Progress in molecular and genetic studies of IgA nephropathy.Journal of Clinical Immunology.  21:310-327. 2001
2001 Tolerance in renal transplantation after allogeneic bone marrow transplantation-6-year follow-up.Transplantation.  71:1681-1683. 2001
2000 Focal posttransplantation lymphoproliferative disorder at the renal allograft hilum.American Journal of Roentgenology.  175:1417-1422. 2000
2000 IgA nephropathy, the most common cause of glomerulonephritis, is linked to 6q22-23.Nature Genetics.  26:354-357. 2000
2000 Treatment of IgA nephropathy.Seminars in Nephrology.  20:277-285. 2000
2000 Postransplant lymphoproliferative disorder localized near the allograft in renal transplantation.Transplantation.  69:809-814. 2000
2000 IgA1 glycosylation and the pathogenesis of IgA nephropathy.American Journal of Kidney Diseases.  35:551-556. 2000
1999 Sirolimus reduces the incidence of acute rejection episodes despite lower cyclosporine doses in caucasian recipients of mismatched primary renal allografts: a phase II trial. Rapamune Study Group.Transplantation.  68:1526-1532. 1999
1999 Circulating immune complexes in IgA nephropathy consist of IgA1 with galactose-deficient hinge region and antiglycan antibodies.Journal of Clinical Investigation.  104:73-81. 1999
1999 Expression of stem cell factor by osteoblasts in normal and hyperparathyroid bone: relation to ectopic mast cell differentiation.Virchows Archiv.  435:50-57. 1999
1999 Parathyroid hormone-regulated production of stem cell factor in human osteoblasts and osteoblast-like cells.Biochemical and Biophysical Research Communications.  255:778-784. 1999
1999 Treatment of immunoglobulin A nephropathy.Annales de Medecine Interne.  150:127-136. 1999
1999 Progress in the pathogenesis of IgA nephropathy.Advances in Nephrology.  29:53-72. 1999
1998 Late expression of tumor necrosis factor-alpha is markedly depressed in patients with IgA nephropathy.Immunological communications.  27:243-255. 1998
1998 Losartan, an angiotensin II type 1 receptor antagonist, lowers hematocrit in posttransplant erythrocytosis.Journal of the American Society of Nephrology.  9:1104-1108. 1998
1998 Epidemiology of IgA nephropathy in central and eastern Kentucky for the period 1975 through 1994. Central Kentucky Region of the Southeastern United States IgA Nephropathy DATABANK Project.Journal of the American Society of Nephrology.  9:853-858. 1998
1997 Renal transplantation in African-American recipients: three decades at a single center.Transplantation Proceedings.  29:3726-3728. 1997
1997 The living donor process in kidney transplantation: influence of race and comorbidity.Transplantation Proceedings.  29:3722-3723. 1997
1997 Angiotensin II stimulates proliferation of normal early erythroid progenitors.Journal of Clinical Investigation.  100:2310-2314. 1997
1997 Galactose-deficient IgA1 in sera of IgA nephropathy patients is present in complexes with IgG.Kidney International.  52:509-516. 1997
1997 Human peritoneal B-1 cells and the influence of continuous ambulatory peritoneal dialysis on peritoneal and peripheral blood mononuclear cell (PBMC) composition and immunoglobulin levels.Clinical and Experimental Immunology.  109:356-361. 1997
1997 The impact of renal transplantation on survival in hepatitis C-positive end-stage renal disease patients.American Journal of Kidney Diseases.  29:608-614. 1997
1996 Benefits of continued cyclosporine through an indigent drug program.American Journal of Kidney Diseases.  28:572-577. 1996
1996 Amlodipine increases cyclosporine levels in hypertensive renal transplant patients: results of a prospective study.Journal of the American Society of Nephrology.  7:831-835. 1996
1996 Dilemmas in renal transplantation: when the clinical course and histological findings differ.American Journal of Kidney Diseases.  27:435-440. 1996
1996 Impact of donor/recipient size matching on outcomes in renal transplantation.Transplantation.  61:383-388. 1996
1996 Angiotensin converting enzyme gene polymorphism: potential silencer motif and impact on progression in IgA nephropathy.Kidney International.  49:571-577. 1996
1996 IgA nephropathy: Defect of glycosylation of IgA1 moleculesJournal of Investigative Medicine.  44. 1996
1995 Complications of the musculoskeletal system in renal transplant recipientsJournal of Nephrology.  8:231-237. 1995
1995 Progress in renal transplantation. A single center study of 3359 patients over 25 years.Annals of Surgery.  221:446-457. 1995
1995 IgA nephropathy. A disease of incomplete IgA 1 glycosylation?Advances in Experimental Medicine and Biology.  376:221. 1995
1995 Intraperitoneal administration of tetanus toxoid elicits a specific response of antibody-secreting cells in the peritoneal cavity.Advances in Experimental Medicine and Biology.  371A:103-106. 1995
1994 Hemolytically inactive C4B complement allotype caused by a proline to leucine mutation in the C5-binding site.Journal of Biological Chemistry.  269:27727-27731. 1994
1994 Erythropoiesis after withdrawal of enalapril in post-transplant erythrocytosis.Kidney International.  46:1397-1403. 1994
1994 Posttransplant erythrocytosis: an enigma revisited.American Journal of Kidney Diseases.  24:1-11. 1994
1994 Intraperitoneal immunization of human subjects with tetanus toxoid induces specific antibody-secreting cells in the peritoneal cavity and in the circulation, but fails to elicit a secretory IgA response.Clinical and Experimental Immunology.  96:356-363. 1994
1994 Immunological studies of IgA nephropathy in blacks reveal elevations of serum IgA2 as well as IgA1.Nephrology Dialysis Transplantation.  9:1324-1329. 1994
1994 Renal retransplantation: the role of race, quadruple immunosuppression, and the flow cytometry cross-match.Transplantation.  57:47-54. 1994
1993 Immunoglobulin A-fibronectin aggregate levels in children and adults with immunoglobulin A nephropathy.American Journal of Kidney Diseases.  22:1-4. 1993
1993 Shared idiotypes in mesangial deposits in IgA nephropathy are not disease-specific.Kidney International.  44:65-74. 1993
1993 Experience with mycophenolate mofetil (RS61443) in renal transplantation at a single center.Annals of Surgery.  217:476-482. 1993
1993 Captopril-induced fall in glomerular filtration rate in cyclosporine-treated hypertensive patients.Journal of the American Society of Nephrology.  3:1570-1574. 1993
1993 Enalapril: safe and effective therapy for posttransplant erythrocytosis.Transplantation Proceedings.  25:1029-1031. 1993
1993 Alternate-day prednisone therapy in IgA nephropathy. Preliminary analysis of a prospective, randomized, controlled trial.Contributions to Nephrology.  104:198-206. 1993
1993 Bone loss after organ transplantationTransplantation reviews.  7:82-95. 1993
1993 Defective galactosylation and clearance of IgA1 molecules as a possible etiopathogenic factor in IgA nephropathy.Contributions to Nephrology.  104:172-182. 1993
1993 Metabolic bone disease in renal transplant recipientsEndocrinologist.  3:415-424. 1993
1993 ReplyAmerican Journal of Kidney Diseases.  21:344. 1993
1993 Tapering or discontinuing cyclosporine for financial reasons--a single-center experience.American Journal of Kidney Diseases.  21:9-15. 1993
1992 Cytokine-induced immunoglobulin production in primary IgA nephropathy.American Journal of Kidney Diseases.  20:611-617. 1992
1992 Binding of serum immunoglobulins to collagens in IgA nephropathy and HIV infection.Kidney International.  42:374-382. 1992
1992 IgA-containing immune complexes after challenge with food antigens in patients with IgA nephropathy.Clinical and Experimental Immunology.  89:315-320. 1992
1992 Benefits of quadruple immunosuppressive therapy in recipients of living related donor kidneys. A review of 855 operations.Annals of Surgery.  215:606-616. 1992
1992 Familial IgA nephropathy associated with bilateral sensorineural deafness.American Journal of Kidney Diseases.  19:592-596. 1992
1992 The impact of the UNOS mandatory sharing policy on recipients of the black and white races--experience at a single renal transplant center.Transplantation.  53:770-774. 1992
1992 Musculoskeletal complications after renal transplantation: pathogenesis and treatment.American Journal of Kidney Diseases.  19:99-120. 1992
1992 Improved survival of primary cadaveric renal allografts in blacks with quadruple immunosuppression.Transplantation.  53:103-109. 1992
1992 ReplyAmerican Journal of Kidney Diseases.  20:531. 1992
1991 Effects of enalapril on erythrocytosis after renal transplantation.Annals of Internal Medicine.  115:954-955. 1991
1991 Selective elevation of monomeric IgA1 in IgA nephropathy patients with normal renal function.American Journal of Kidney Diseases.  18:313-319. 1991
1991 Rapid loss of vertebral mineral density after renal transplantation.New England Journal of Medicine.  325:544-550. 1991
1991 C4A deficiency and poor prognosis in patients with IgA nephropathy.Clinical Nephrology.  36:1-5. 1991
1991 IgA nephropathy in blacks: studies of IgA2 allotypes and clinical course.Kidney International.  39:1218-1224. 1991
1991 Macroscopic hematuria and proteinuria preceding renal IgA deposition in patients with IgA nephropathy.American Journal of Kidney Diseases.  17:472-479. 1991
1991 Are black living-related renal donors at greater long-term risk of renal complications than white donors?Transplantation Proceedings.  23:1328-1329. 1991
1991 Role for specific complement phenotypes and deficiencies in the clinical expression of IgA nephropathy.American Journal of the Medical Sciences.  301:115-123. 1991
1991 Analysis of 22 years experience in living-related transplantation at the University of Alabama in Birmingham.Clinical Transplants.  179-191. 1991
1991 Epstein-Barr virus transformation of B lymphocytes from IgA nephropathy patients and first-degree relatives results in increased immunoglobulin synthesis not restricted to IgA.American Journal of Kidney Diseases.  17:55-61. 1991
1991 Long-term results of a controlled prospective study with transfusion of donor-specific bone marrow in 57 cadaveric renal allograft recipients.Transplantation.  51:70-75. 1991
1991 OKT3 first-dose reaction: association with T cell subsets and cytokine release.Kidney International.  39:141-148. 1991
1990 Cyclosporine-induced changes in glomerular filtration rate and urea excretion.American Journal of Medicine.  88:497-502. 1990
1990 Regional variation in C4 phenotype in patients with IgA nephropathy.Journal of Pediatrics.  116:S72-S77. 1990
1990 J. chain disease: a novel form of plasma cell dyscrasia.American Journal of Medicine.  88:411-416. 1990
1990 C4B deficiency in two siblings with IgA nephropathy.American Journal of Kidney Diseases.  15:66-71. 1990
1990 Cyclosporine-induced changes in glomerular filtration rate and urea excretionAmerican Journal of Medicine.  88:503-511. 1990
1990 Donor antigen-specific immunosuppression in cadaveric and living-related donor kidney allograft recipients.Clinical Transplants.  289-300. 1990
1989 Successful renal allografts in recipients with a positive standard, DTE negative cross-match.Transplantation Proceedings.  21:746-747. 1989
1989 Successful renal allografts in recipients with crossmatch-positive, dithioerythritol-treated negative sera. Race, transplant history, and HLA-DR1 phenotype.Transplantation.  47:240-245. 1989
1989 Sustained high panel reactive antibody levels in highly sensitized patients: significance of continued transfusions.Transplantation Proceedings.  21:771-772. 1989
1989 NON-SPECIFIC MESANGIAL STAINING WITH ANTIBODIES AGAINST CYTOMEGALOVIRUS IN IMMUNOGLOBULIN-A NEPHROPATHYLancet.  333:129-131. 1989
1989 Non-specific mesangial staining with antibodies against cytomegalovirus in immunoglobulin-A nephropathy.Lancet.  1:129-131. 1989
1989 Use of cryopreserved donor bone marrow in cadaver kidney allograft recipients.Transplantation.  47:66-71. 1989
1988 Activation of complement in IgA nephropathy.American Journal of Kidney Diseases.  12:437-442. 1988
1988 Familial clustering and immunogenetic aspects of IgA nephropathy.American Journal of Kidney Diseases.  12:366-370. 1988
1988 Bilateral cavernous sinus thrombosis due to mucormycosis.Archives of Ophthalmology -New Series-.  106:1089-1092. 1988
1988 On the mechanism by which chloride corrects metabolic alkalosis in man.American Journal of Medicine.  84:449-458. 1988
1988 A comparison of OKT3 monoclonal antibody and corticosteroids in the treatment of acute renal allograft rejection.American Journal of Kidney Diseases.  11:86-89. 1988
1988 Early graft loss in cyclosporine A-treated cadaveric renal allograft recipients receiving retransplants against previous mismatched HLA-A, -B, -DR donor antigensTransplantation Proceedings.  20:170-172. 1988
1988 IgA nephropathy, the most common glomerulonephritis worldwide. A neglected disease in the United States?American Journal of Medicine.  84:129-132. 1988
1987 Analysis of immunoglobulin heavy chain restriction fragment length polymorphisms in IgA nephropathy.Seminars in Nephrology.  7:306-310. 1987
1987 IgA-associated renal diseases: immunochemical studies of IgA1 proteins, circulating immune complexes, and cellular interactions.Seminars in Nephrology.  7:332-335. 1987
1987 Immunogenetic markers as prognostic features in patients from Kentucky with IgA nephropathy.Seminars in Nephrology.  7:389-392. 1987
1987 Aberrant synthesis of antibodies directed at the Fab fragment of IgA in patients with IgA nephropathies.Clinical immunology and immunopathology.  45:208-213. 1987
1987 Fatal Rhizopus infections in hemodialysis patients receiving deferoxamine.Annals of Internal Medicine.  107:678-680. 1987
1987 Striking elevation of serum IgA, IgA-containing immune complexes, and IgA rheumatoid factor in clinically silent dermatitis herpetiformis.American Journal of Kidney Diseases.  10:378-384. 1987
1987 A major gene model for the familial aggregation of plasma IgA concentration.American Journal of Medical Genetics.  27:857-866. 1987
1987 Regionalization in hereditary IgA nephropathy.American Journal of Human Genetics.  41:36-50. 1987
1987 Oxalosis in bone causing a radiographical mimicry of renal osteodystrophy.American Journal of Kidney Diseases.  9:436-440. 1987
1987 Morphologic and immunohistochemical observations in granulomatous glomerulonephritis.American Journal of Pathology.  126:581-591. 1987
1987 Antibodies directed at Fab of IgA in the sera of normal individuals and IgA nephropathy patients.Advances in Experimental Medicine and Biology.  216B:1537-1544. 1987
1987 Complement activation in IgA nephropathyKidney International.  31:1019-1023. 1987
1987 Complement phenotypes (C3 and C4) in IgA nephropathy.Advances in Experimental Medicine and Biology.  216B:1569-1575. 1987
1987 Detection of food antigen-specific IgA immune complexes in human sera.Advances in Experimental Medicine and Biology.  216A:813-820. 1987
1987 Genetic factors in primary IgA nephropathy.Nephrology Dialysis Transplantation.  2:134-142. 1987
1987 Immunological studies of IgA nephropathy: familial and racial aspects.Advances in Experimental Medicine and Biology.  216B:1489-1498. 1987
1987 Influence of race on renal allograft survival in the pre- and postcyclosporine era.Clinical Transplants.  217-233. 1987
1986 Aluminum-associated renal osteodystrophy.The Alabama journal of medical sciences.  23:414-419. 1986
1986 Circulating immune complexes and immunoglobulin A rheumatoid factor in patients with mesangial immunoglobulin A nephropathies.Journal of Clinical Investigation.  77:1931-1938. 1986
1986 Aluminum-related bone disease in mild and advanced renal failure: evidence for high prevalence and morbidity and studies on etiology and diagnosis.American Journal of Nephrology.  6:275-283. 1986
1986 IgA-associated renal diseases: antibodies to environmental antigens in sera and deposition of immunoglobulins and antigens in glomeruli.Journal of Clinical Immunology.  6:74-86. 1986
1985 Familial IgA nephropathy.New England Journal of Medicine.  313:186. 1985
1985 Focal sclerosis of hypertrophied glomeruli in solitary functioning kidneys of humans.American Journal of Kidney Diseases.  5:226-232. 1985
1985 Familial IgA Nephropathy: Evidence of an Inherited Mechanism of DiseaseNew England Journal of Medicine.  312:202-208. 1985
1985 The immunogenetics of IgA nephropathyPlasma Therapy and Transfusion Technology.  6:687-704. 1985
1984 Complement phenotypes in glomerulonephritis: increased frequency of homozygous null C4 phenotypes in IgA nephropathy and Henoch-Schönlein purpura.Kidney International.  26:855-860. 1984
1984 IgA Nephropathy: Presentation, Clinical Course, and Prognosis in Children and AdultsAmerican Journal of Kidney Diseases.  4:192-200. 1984
1984 Increased frequency of C3 fast alleles in IgA nephropathyDisease Markers.  2:419-428. 1984
1983 Serum complement proteins in IgA nephropathy.Clinical Nephrology.  20:251-258. 1983
1982 Renin and aldosterone responses to short-term NaCl or NaHCO3 loading in man.Journal of Laboratory and Clinical Medicine.  100:261-268. 1982
1982 Partial H (beta 1H) deficiency and glomerulonephritis in two families.Journal of Clinical Immunology.  2:110-117. 1982
1981 Properdin deficiency with IgA nephropathy.New England Journal of Medicine.  305:1097. 1981

Chapter

Year Title Altmetric
2016 Heterogeneity of aberrant O-glycosylation of IgA1 in IgA nephropathy.  53-68. 2016
2015 IgA Nephropathy and Related Diseases.  2023-2038. 2015
2009 Clinicopathologic findings.  83-106. 2009

Research Overview

  • IgA nephropathy
    Kidney transplantation
  • Investigator On

  • Private Grant  awarded by CALLIDITAS THERAPEUTICS AB 2019 - 2026
  • Private Grant  awarded by CSL BEHRING, LLC 2017 - 2022
  • Private Grant  awarded by MALLINCKRODT, INC. 2017 - 2022
  • Novel Therapies to Modulate the Inflammatory Alloresponse in Renal Grafts  awarded by University of California, San Francisco 2014 - 2021
  • Private Grant  awarded by QUARK PHARMACEUTICALS, INC. 2015 - 2020
  • Private Grant  awarded by ALEXION PHARMACEUTICALS, INC. 2018 - 2020
  • Abnormal STAT3 Signaling and Aberrant O-Glycosylation of IgA1 in IgA Nephropathy  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2015 - 2020
  • Analytical Tools for the Analysis of Clustered O-Glycans in Clinical Samples  awarded by National Institute of General Medical Sciences/NIH/DHHS 2016 - 2020
  • Genetics of IgA Nephropathy by Integrative Network-Based Association Studies  awarded by Columbia University 2015 - 2020
  • Genetic, Environmental & Histologic Basis for Kidney Disease Risk among Persons Living with HIV  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2018 - 2019
  • Effects of Inhibiting Early Inflammation in Kidney Transplant Patients - Equipment  awarded by Mount Sinai School of Medicine 2015 - 2019
  • Molecular Basis of Pathogenicity of IgA1-containing Immune Complexes  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2012 - 2019
  • Elucidating IgA Nephropathy Through Genetic Studies of IgA1 Glycosylation  awarded by Columbia University 2014 - 2019
  • UAB Center for AIDS Research  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS 2014 - 2019
  • Aptamers-Based Arrays for Detection of Pathogenic IgA 1 O-Glycoforms in IgA Nephropathy  awarded by Columbia University 2016 - 2018
  • IgA Nephropathy: Interventions with Generation of Nephritogenic Immune Complexes  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2014 - 2018
  • Private Grant  awarded by ALEXION PHARMACEUTICALS, INC. 2014 - 2017
  • Preserving Renal Function & Protective Immunity via Anti-LFA-1-Based CNI Avoidance  awarded by Emory University 2009 - 2016
  • Analytical Tools for the Analysis of Clustered O-Glycans in Clinical Samples  awarded by National Institute of General Medical Sciences/NIH/DHHS 2011 - 2016
  • Private Grant  awarded by ANTHERA PHARMACEUTICALS, INC 2015 - 2016
  • Private Grant  awarded by Pfizer Pharmaceuticals 2013 - 2015
  • Elucidating IgA Nephropathy Through Genetic Studies of IgA1 Glycosylation  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2009 - 2014
  • New Animal Model for Studies of Mucosal Immunity and IgA Nephropathy  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2010 - 2013
  • Full Name

  • Bruce Julian
  • Blazerid

  • bjulian