Positions

Selected Publications

Academic Article

Year Title Altmetric
2019 Health-related quality of life in glomerular diseaseKidney International.  95:1209-1224. 2019
2019 CureGN Study Rationale, Design, and Methods: Establishing a Large Prospective Observational Study of Glomerular DiseaseOregon Social Studies Journal.  73:218-229. 2019
2019 Autoantibodies Specific for Galactose-Deficient IgA1 in IgA Vasculitis With NephritisKidney International Reports2019
2019 Glomerular immunodeposits of patients with IgA nephropathy are enriched for IgG autoantibodies specific for galactose-deficient IgA1Journal of the American Society of Nephrology.  30:2017-2026. 2019
2019 The emerging role of complement proteins as a target for therapy of IgA nephropathyFrontiers in Immunology.  10. 2019
2018 Population Health, Ethnicity, and Rate of Living Donor Kidney TransplantationTransplantation.  102:2080-2087. 2018
2018 Clinical Characteristics and Treatment Patterns of Children and Adults With IgA Nephropathy or IgA Vasculitis: Findings From the CureGN StudyKidney International Reports.  3:1373-1384. 2018
2018 Secondary IgA nephropathyKidney International.  94:674-681. 2018
2018 Aberrant Glycosylation of the IgA1 Molecule in IgA NephropathySeminars in Nephrology.  38:461-476. 2018
2018 Genome-wide association studies suggest that APOL1-environment interactions more likely trigger kidney disease in African Americans with nondiabetic nephropathy than strong APOL1–second gene interactionsKidney International.  94:599-607. 2018
2018 Assay for galactose-deficient IgA1 enables mechanistic studies with primary cells from IgA nephropathy patientsJournal of Medical Internet Research.  65:71-77. 2018
2018 Apolipoprotein L1 and Chronic Kidney Disease Risk in Young Potential Living Kidney DonorsActa Neuropsychiatrica.  267:1161-1168. 2018
2018 Redefining the Influence of Ethnicity on Simultaneous Kidney and Pancreas Transplantation Outcomes: A 15-Year Single-Center Experience.Acta Neuropsychiatrica2018
2018 Evaluation of potential living kidney donors in the APOL1 eraJournal of the American Society of Nephrology.  29:1079-1081. 2018
2018 Life Expectancy for Patients From the Southeastern United States With IgA NephropathyKidney International Reports.  3:99-104. 2018
2018 Serum galactose-deficient-IgA1 and IgG autoantibodies correlate in patients with IgA nephropathyPLoS ONE.  13. 2018
2017 Noninvasive diagnosis of chronic kidney diseases using urinary proteome analysisNephrology Dialysis Transplantation.  32:2079-2089. 2017
2017 Apolipoprotein L1 Gene Effects on Kidney TransplantationSeminars in Nephrology.  37:530-537. 2017
2017 Influence of Kidney Transplant Status on Warfarin Dose, Anticoagulation Control, and Risk of HemorrhagePharmacotherapy: The Journal of Human Pharmacology and Drug Therapy.  37:1366-1373. 2017
2017 Effect of Replacing Race With Apolipoprotein L1 Genotype in Calculation of Kidney Donor Risk IndexAmerican Journal of Biochemistry and Biotechnology.  17:1540-1548. 2017
2017 Prognostic value of serum biomarkers of autoimmunity for recurrence of IGA nephropathy after kidney transplantationJournal of the American Society of Nephrology.  28:1943-1950. 2017
2017 A randomized, controlled trial of rituximab in IgA nephropathy with proteinuria and renal dysfunctionJournal of the American Society of Nephrology.  28:1306-1313. 2017
2017 GWAS for serum galactose-deficient IgA1 implicates critical genes of the O-glycosylation pathwayPLoS Genetics.  13. 2017
2017 Evidence from the Oxford Classification cohort supports the clinical value of subclassification of focal segmental glomerulosclerosis in IgA nephropathyKidney International.  91:235-243. 2017
2017 Inhibition of STAT3 Signaling Reduces IgA1 Autoantigen Production in IgA NephropathyKidney International Reports.  2:1194-1207. 2017
2017 Serial Galactose-Deficient IgA1 Levels in Children with IgA Nephropathy and Healthy ControlsInternational Journal of Nephrology.  2017. 2017
2016 The origin and activities of IgA1-containing immune complexes in IGA nephropathyFrontiers in Immunology.  7. 2016
2016 Deceased-donor apolipoprotein L1 renal-risk variants have minimal effects on liver transplant outcomesPLoS ONE.  11. 2016
2016 APOL1 genotype and kidney transplantation outcomes from deceased african American donorsTransplantation.  100:194-202. 2016
2016 Galactose-Deficient IgA1 as a Candidate Urinary Polypeptide Marker of IgA Nephropathy?Journal Of Practical Global Business.  2016. 2016
2016 Somatic mutations modulate autoantibodies against galactose-deficient IgA1 in IgA nephropathyJournal of the American Society of Nephrology.  27:3278-3284. 2016
2016 The MEST score provides earlier risk prediction in lgA nephropathyKidney International.  89:167-175. 2016
2016 Toward Noninvasive Diagnosis of IgA Nephropathy: A Pilot Urinary Metabolomic and Proteomic StudyJournal Of Practical Global Business.  2016. 2016
2015 Deceased donor multidrug resistance protein 1 and caveolin 1 gene variants may influence allograft survival in kidney transplantationKidney International.  88:584-592. 2015
2015 New Insights into the Pathogenesis of IgA Nephropathy.Kidney Diseases.  1:8-18. 2015
2015 Should kidney donors be genotyped for APOL1 risk alleles?Kidney International.  87:671-673. 2015
2015 Apolipoprotein L1 gene variants in deceased organ donors are associated with renal allograft failureAmerican Journal of Biochemistry and Biotechnology.  15:1615-1622. 2015
2015 Current understanding of the role of complement in IgA nephropathyJournal of the American Society of Nephrology.  26:1503-1512. 2015
2015 N-Acetylgalactosaminide α2,6-sialyltransferase II is a candidate enzyme for sialylation of galactose-deficient IgA1, the key autoantigen in IgA nephropathyNephrology Dialysis Transplantation.  30:234-238. 2015
2014 Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogensNature Genetics.  46:1187-1196. 2014
2014 Cellular Signaling and Production of Galactose-Deficient IgA1 in IgA Nephropathy, an Autoimmune DiseaseJournal of Immunology Research.  2014. 2014
2014 Enzymatic sialylation of IgA1 O-glycans: Implications for studies of IgA nephropathyPLoS ONE.  9. 2014
2014 A panel of serum biomarkers differentiates IgA nephropathy from other renal diseasesPLoS ONE.  9. 2014
2014 Immune profile of IgA-dominant diffuse proliferative glomerulonephritisJournal of Allied Health.  7:479-483. 2014
2014 Cytokines alter IgA1 O-glycosylation by dysregulating C1GalT1 and ST6GalNAc-II enzymesJournal of Biological Chemistry.  289:5330-5339. 2014
2014 End-stage renal disease in African Americans with lupus nephritis is associated with APOL1International Journal of Parallel Programming.  66:390-396. 2014
2013 Biomarkers in IgA nephropathy: Relationship to pathogenetic hitsExpert Opinion on Medical Diagnostics.  7:615-627. 2013
2013 Pathogenesis of immunoglobulin A nephropathyJournal of Commodity Science and Technology.  22:287-294. 2013
2013 IgA nephropathy: Molecular mechanisms of the diseaseHartford Center for Geriatric Nursing Excellence at PSU.  8:217-240. 2013
2013 MEdical progress: IgA nephropathyNew England Journal of Medicine.  368:2402-2414. 2013
2012 The IgA1 immune complex-mediated activation of the MAPK/ERK kinase pathway in mesangial cells is associated with glomerular damage in IgA nephropathyKidney International.  82:1284-1296. 2012
2012 Association of IgG co-deposition with serum levels of galactose-deficient IgA1 in pediatric IgA nephropathy.Periodicum Biologorum.  78:465-469. 2012
2012 In vitro-generated immune complexes containing galactose-deficient IgA1 stimulate proliferation of mesangial cellsResults in Immunology.  2:166-172. 2012
2012 Serum galactose-deficient IgA1 level is not associated with proteinuria in children with IgA nephropathyInternational Journal of Nephrology.  2012. 2012
2012 Autoantibodies targeting galactose-deficient IgA1 associate with progression of IgA nephropathyJournal of the American Society of Nephrology.  23:1579-1587. 2012
2012 Geographic differences in genetic susceptibility to IgA nephropathy: GWAS replication study and geospatial risk analysisPLoS Genetics.  8. 2012
2012 Reply to "genetic determinants of mycophenolate-related anemia and leukopenia after transplantation"Transplantation.  93. 2012
2012 Glycosylation of IgA1 and pathogenesis of IgA nephropathySpringer Seminars in Immunopathology.  34:365-382. 2012
2012 Naturally occurring structural isomers in serum IgA1 O -glycosylationJournal of Proteome Research.  11:692-702. 2012
2012 Association of IgG co-deposition with serum levels of galactose-deficient IgA1 in pediatric IgA nephropathyPeriodicum Biologorum.  78:465-469. 2012
2012 Erratum: Mice overexpressing BAFF develop a commensal flora-dependent, IgA-associated nephropathy (Journal of Clinical Investigation (2011) 121, 10 (3991-4002) DOI: 10.1172/JCI45563)Journal of Clinical Investigation.  122:778. 2012
2011 Membrane-assisted online renaturation for automated microfluidic lectin blottingJournal of the American Chemical Society.  133:19610-19613. 2011
2011 Sugars and alcohol: IgA-associated renal diseases in alcoholic cirrhosisKidney International.  80:1252-1254. 2011
2011 APOL1 variants increase risk for FSGS and HIVAN but not IgA nephropathyJournal of the American Society of Nephrology.  22:1991-1996. 2011
2011 IgA1 immune complexes from pediatric patients with IgA nephropathy activate cultured human mesangial cellsNephrology Dialysis Transplantation.  26:3451-3457. 2011
2011 Mice overexpressing BAFF develop a commensal flora-dependent, IgA-associated nephropathyJournal of Clinical Investigation.  121:3991-4002. 2011
2011 The pathophysiology of IgA nephropathyJournal of the American Society of Nephrology.  22:1795-1803. 2011
2011 Aberrant glycosylation of iga1 and anti-glycan antibodies in iga nephropathy: Role of mucosal immune systemPolity.  72:60-63. 2011
2011 Oxidative stress and galactose-deficient IgA1 as markers of progression in IgA nephropathyPediatric and Developmental Pathology.  6:1903-1911. 2011
2011 Validation of the Oxford classification of IgA nephropathyKidney International.  80:310-317. 2011
2011 Genetic determinants of mycophenolate-related anemia and leukopenia after transplantationTransplantation.  91:309-316. 2011
2011 Novel polymorphisms associated with tacrolimus trough concentrations: Results from a multicenter kidney transplant consortiumTransplantation.  91:300-308. 2011
2011 Genome-wide association study identifies susceptibility loci for IgA nephropathyNature Genetics.  43:321-329. 2011
2011 Aberrant glycosylation of IgA1 is inherited in both pediatric IgA nephropathy and Henoch-Schönlein purpura nephritisKidney International.  80:79-87. 2011
2010 Clustered O-glycans of IgA1: Defining macro- and microheterogeneity by use of electron capture/transfer dissociationMolecular and Cellular Proteomics.  9:2545-2557. 2010
2010 Galactose-deficient IgA1 in African Americans with IgA nephropathy: Serum levels and heritabilityPediatric and Developmental Pathology.  5:2069-2074. 2010
2010 Genetic studies of IgA nephropathy: Past, present, and futurePediatric Nephrology.  25:2257-2268. 2010
2010 Recommendations for biomarker identification and qualification in clinical proteomicsScience Translational Medicine.  2. 2010
2010 Recognition of galactose-deficient O-glycans in the hinge region of IgA1 by N-acetylgalactosamine-specific snail lectins: A comparative binding study.Biomarker Insights.  49:5671-5682. 2010
2010 Glomerulonephritis after hematopoietic cell transplantation: IgA nephropathy with increased excretion of galactose-deficient IgA1Nephrology Dialysis Transplantation.  25:1708-1713. 2010
2010 Tissue distribution and biological activities of immune complexes are determined by their size and compositionNephrology Dialysis Transplantation.  25:1007. 2010
2010 Familial IgA nephropathy in southeastern Kentucky.Periodicum Biologorum.  73:115-121. 2010
2010 Familial IgA nephropathy in southeastern KentuckyPeriodicum Biologorum.  73:115-121. 2010
2010 Naturally occurring human urinary peptides for use in diagnosis of chronic kidney diseaseMolecular and Cellular Proteomics.  9:2424-2437. 2010
2010 The Oxford IgA nephropathy clinicopathological classification is valid for children as well as adultsKidney International.  77:921-927. 2010
2009 Application of proteomic analysis to renal disease in the clinicPROTEOMICS - Clinical Applications.  3:1023-1028. 2009
2009 Sources of urinary proteins and their analysis by urinary proteomics for the detection of biomarkers of diseasePROTEOMICS - Clinical Applications.  3:1029-1043. 2009
2009 Risk factors and impact of recurrent lupus nephritis in patients with systemic lupus erythematosus undergoing renal transplantation: Data from a single US institutionCancer Genetics and Cytogenetics.  60:2757-2766. 2009
2009 The Oxford classification of IgA nephropathy: Pathology definitions, correlations, and reproducibilityKidney International.  76:546-556. 2009
2009 The Oxford classification of IgA nephropathy: Rationale, clinicopathological correlations, and classificationKidney International.  76:534-545. 2009
2009 Secondary listing for deceased-donor kidney transplantation does not increase likelihood of engraftment at a large transplant center: Brief communicationAmerican Journal of Biochemistry and Biotechnology.  9:1671-1673. 2009
2009 Aberrantly glycosylated IgA1 in IgA nephropathy patients is recognized by IgG antibodies with restricted heterogeneityJournal of Clinical Investigation.  119:1668-1677. 2009
2009 Isolated central nervous system posttransplant lymphoproliferative disorder treated with high-dose intravenous methotrexateAmerican Journal of Biochemistry and Biotechnology.  9:1243-1248. 2009
2008 CE-MS analysis of the human urinary proteome for biomarker discovery and disease diagnosticsPROTEOMICS - Clinical Applications.  2:964-973. 2008
2008 Urinary proteomics in diabetes and CKDJournal of the American Society of Nephrology.  19:1283-1290. 2008
2008 Systolic dysfunction portends increased mortality among those waiting for renal transplantJournal of the American Society of Nephrology.  19:1190-1196. 2008
2008 Aberrant IgA1 glycosylation is inherited in familial and sporadic IgA nephropathyJournal of the American Society of Nephrology.  19:1008-1014. 2008
2008 IgA1-secreting cell lines from patients with IgA nephropathy produce aberrantly glycosylated IgA1Journal of Clinical Investigation.  118:629-639. 2008
2008 Role of aberrant glycosylation of IgA1 molecules in the pathogenesis of iga nephropathyKidney and Blood Pressure Research.  31:29-37. 2008
2008 IgA Glycosylation and IgA Immune Complexes in the Pathogenesis of IgA NephropathySeminars in Nephrology.  28:78-87. 2008
2007 Electrophoretic methods for analysis of urinary polypeptides in lgA-associated renal diseasesSA Journal of Accounting Research.  28:4469-4483. 2007
2007 Serum levels of galactose-deficient IgA in children with IgA nephropathy and Henoch-Schönlein purpuraPediatric Nephrology.  22:2067-2072. 2007
2007 Analysis of O-glycan heterogeneity in IgA1 myeloma proteins by Fourier transform ion cyclotron resonance mass spectrometry: Implications for IgA nephropathyFresenius' Journal of Analytical Chemistry.  389:1397-1407. 2007
2007 Urinary biomarkers of IgA nephropathy and other IgA-associated renal diseasesWorld Journal of Urology.  25:467-476. 2007
2007 High-resolution proteome/peptidome analysis of peptides and low-molecular-weight proteins in urinePROTEOMICS - Clinical Applications.  1:792-804. 2007
2007 Patients with IgA nephropathy have increased serum galactose-deficient IgA1 levelsKidney International.  71:1148-1154. 2007
2007 The genetics of IgA nephropathyNature Clinical Practice Nephrology.  3:325-338. 2007
2007 IgA nephropathy and henoch-schoenlein purpura nephritis: Aberrant glycosylation of IgA1, formation of IgA1-containing immune complexes, and activation of mesangial cellsNature Clinical Practice Gastroenterology and Hepatology.  157:134-138. 2007
2007 IgA nephropathy: A clinical overviewNature Clinical Practice Gastroenterology and Hepatology.  157:19-26. 2007
2007 IgA nephropathy: Characterization of IgG antibodies specific for galactose-deficient IgA1Nature Clinical Practice Gastroenterology and Hepatology.  157:129-133. 2007
2007 IgA nephropathy: Current views of immune complex formationNature Clinical Practice Gastroenterology and Hepatology.  157:56-63. 2007
2007 Identification and Characterization of CMP-NeuAc:GalNAc-IgA1 α2,6-Sialyltransferase in IgA1-producing CellsJournal of Molecular Biology.  369:69-78. 2007
2007 Reactivities of N-acetylgalactosamine-specific lectins with human IgA1 proteinsMolecular Immunology.  44:2598-2604. 2007
2007 Clinical proteomics: A need to define the field and to begin to set adequate standardsPROTEOMICS - Clinical Applications.  1:148-156. 2007
2006 IgA-containing immune complexes in the urine of IgA nephropathy patientsNephrology Dialysis Transplantation.  21:2478-2484. 2006
2006 Brief communication: Glomerulonephritis in patients with hepatitis C cirrhosis undergoing liver transplantationThrombosis.  144:735-741. 2006
2006 Clinical trial to evaluate omega-3 fatty acids and alternate day prednisone in patients with IgA nephropathy: report from the Southwest Pediatric Nephrology Study Group.Pediatric and Developmental Pathology.  1:467-474. 2006
2005 Recurrent IgA nephropathy after renal transplantation despite immunosuppressive regimens with mycophenolate mofetilNephrology Dialysis Transplantation.  20:1214-1221. 2005
2005 IgA1-containing immune complexes in IgA nephropathy differentially affect proliferation of mesangial cellsKidney International.  67:504-513. 2005
2004 IgA nephropathy: An updateJournal of Commodity Science and Technology.  13:171-179. 2004
2004 Angiotensin II Receptor Type 1 Expression in Erythroid Progenitors: Implications for the Pathogenesis of Postrenal Transplant ErythrocytosisSeminars in Nephrology.  24:120-130. 2004
2004 Incidence of hip osteonecrosis among renal transplantation recipients: A prospective studyGeometric Modelling.  59:431-438. 2004
2003 Bone mineral density changes within six months of renal transplantationTransplantation.  75:49-54. 2003
2003 Bone mineral density changes within six months of renal transplantation.Transplantation.  75:49-54. 2003
2002 Interactions of human mesangial cells with IgA and IgA-containing immune complexesKidney International.  62:465-475. 2002
2001 Progress in molecular and genetic studies of IgA nephropathyJournal of Clinical Immunology.  21:310-327. 2001
2001 Tolerance in renal transplantation after allogeneic bone marrow transplantation-6-year follow-upTransplantation.  71:1681-1683. 2001
2000 IgA nephropathy, the most common cause of glomerulonephritis, is linked to 6q22-23Nature Genetics.  26:354-357. 2000
2000 Treatment of IgA nephropathySeminars in Nephrology.  20:277-285. 2000
2000 Posttransplant lymphoproliferative disorder localized near the allograft in renal transplantationTransplantation.  69:809-814. 2000
2000 Focal posttransplantation lymphoproliferative disorder at the renal allograft hilumInternational Journal of Molecular Medicine.  175:1417-1422. 2000
2000 IgA1 glycosylation and the pathogenesis of IgA nephropathyOregon Social Studies Journal.  35:551-554. 2000
1999 Sirolimus reduces the incidence of acute rejection episodes despite lower cyclosporine doses in caucasian recipients of mismatched primary renal allografts: A phase II trialTransplantation.  68:1526-1532. 1999
1999 Expression of stem cell factor by osteoblasts in normal and hyperparathyroid bone: Relation to ectopic mast cell differentiationVirchows Archiv.  435:50-57. 1999
1999 Parathyroid hormone-regulated production of stem cell factor in human osteoblasts and osteoblast-like cellsJournal of Healthcare Leadership.  255:778-784. 1999
1999 Circulating immune complexes in IgA nephropathy consist of IgA1 with galactose-deficient hinge region and antiglycan antibodiesJournal of Clinical Investigation.  104:73-81. 1999
1999 Progress in the pathogenesis of IgA nephropathy.Drugs and Alcohol Today.  29:53-72. 1999
1999 Treatment of immunoglobulin A nephropathyIEEE Transactions on Smart Grid.  150:127-136. 1999
1998 Losartan, an Angiotensin II type 1 receptor antagonist, lowers hematocrit in posttransplant erythrocytosisJournal of the American Society of Nephrology.  9:1104-1108. 1998
1998 Epidemiology of IgA nephropathy in central and eastern Kentucky for the period 1975 through 1994Journal of the American Society of Nephrology.  9:853-858. 1998
1998 Late expression of tumor necrosis factor-α is markedly depressed in patients with IgA nephropathyImmunological communications.  27:243-255. 1998
1997 Renal transplantation in African-American recipients: three decades at a single center.Transplantation Proceedings.  29:3726-3728. 1997
1997 The living donor process in kidney transplantation: influence of race and comorbidity.Transplantation Proceedings.  29:3722-3723. 1997
1997 Angiotensin II stimulates proliferation of normal early erythroid progenitorsJournal of Clinical Investigation.  100:2310-2314. 1997
1997 Galactose-deficient IgA1 in sera of IgA nephropathy patients is present in complexes with IgGKidney International.  52:509-516. 1997
1997 Human peritoneal B-1 cells and the influence of continuous ambulatory peritoneal dialysis on peritoneal and peripheral blood mononuclear cell (PBMC) composition and immunoglobulin levelsMol. Biol. Cell.  109:356-361. 1997
1997 The impact of renal transplantation on survival in hepatitis C- positive end-stage renal disease patientsOregon Social Studies Journal.  29:608-614. 1997
1996 Amlodipine increases cyclosporine levels in hypertensive renal transplant patients: Results of a prospective studyJournal of the American Society of Nephrology.  7:831-835. 1996
1996 Impact of donor/recipient size matching on outcomes in renal transplantationTransplantation.  61:383-388. 1996
1996 Angiotensin converting enzyme gene polymorphism: Potential silencer motif and impact on progression in IgA nephropathyKidney International.  49:571-577. 1996
1996 Benefits of continued cyclosporine through an indigent drug programOregon Social Studies Journal.  28:572-577. 1996
1996 Dilemmas in renal transplantation: When the clinical course and histological findings differOregon Social Studies Journal.  27:435-440. 1996
1996 IgA nephropathy: Defect of glycosylation of IgA1 moleculesJournal of Investigative Medicine.  44. 1996
1995 Complications of the musculoskeletal system in renal transplant recipientsJournal of Nephrology.  8:231-237. 1995
1995 IgA nephropathy: A disease of incomplete IgA 1 glycosylation?Transplantation.  376:221-222. 1995
1995 Intraperitoneal administration of tetanus toxoid elicits a specific responses of antibody-secreting cells in the peritoneal cavityTransplantation.  371:103-106. 1995
1995 Progress in Renal Transplantation a Single Center Study of 3359 Patients over 25 YearsActa Neuropsychiatrica.  221:446-458. 1995
1994 Hemolytically inactive C4B complement allotype caused by a proline to leucine mutation in the C5-binding siteJournal of Biological Chemistry.  269:27727-27731. 1994
1994 Erythropoiesis after withdrawal of enalapril in post-transplant erythrocytosisKidney International.  46:1397-1403. 1994
1994 Immunological studies of IgA nephropathy in blacks reveal elevations of serum IgA2 as well as IgA1Nephrology Dialysis Transplantation.  9:1324-1329. 1994
1994 Intraperitoneal immunization of human subjects with tetanus toxoid induces specific antibody-secreting cells in the peritoneal cavity and in the circulation, but fails to elicit a secretory IgA responseMol. Biol. Cell.  96:356-363. 1994
1994 Posttransplant Erythrocytosis: An Enigma RevisitedOregon Social Studies Journal.  24:1-11. 1994
1994 Renal retransplantation: The role of race, quadruple immunosuppression, and the flow cytometry cross-matchTransplantation.  57:47-54. 1994
1993 Captopril-induced fall in glomerular filtration rate in cyclosporine-treated hypertensive patientsJournal of the American Society of Nephrology.  3:1570-1574. 1993
1993 Enalapril: safe and effective therapy for posttransplant erythrocytosis.Transplantation Proceedings.  25:1029-1031. 1993
1993 Alternate-day prednisone therapy in IgA nephropathy. Preliminary analysis of a prospective, randomized, controlled trial.Nature Clinical Practice Gastroenterology and Hepatology.  104:198-206. 1993
1993 Bone loss after organ transplantationTransplantation Reviews.  7:82-95. 1993
1993 Defective galactosylation and clearance of IgA1 molecules as a possible etiopathogenic factor in IgA nephropathy.Nature Clinical Practice Gastroenterology and Hepatology.  104:172-182. 1993
1993 Experience with mycophenolate mofetil (RS61443) in renal transplantation at a single centerActa Neuropsychiatrica.  217:476-484. 1993
1993 Immunoglobulin A-Fibronectin Aggregate Levels in Children and Adults With Immunoglobulin A NephropathyOregon Social Studies Journal.  22:1-4. 1993
1993 Metabolic bone disease in renal transplant recipientsJournal Of Energy, Finance & Development.  3:415-424. 1993
1993 ReplyOregon Social Studies Journal.  21:344. 1993
1993 Shared idiotypes in mesangial deposits in IgA nephropathy are not disease-specificKidney International.  44:65-74. 1993
1993 Tapering or Discontinuing Cyclosporine for Financial Reasons—A Single-Center ExperienceOregon Social Studies Journal.  21:9-15. 1993
1992 Benefits of quadruple immunosuppressive therapy in recipients of living related donor kidneys: A review of 855 operationsActa Neuropsychiatrica.  215:606-617. 1992
1992 Binding of serum immunoglobulins to collagens in IgA nephropathy and HIV infectionKidney International.  42:374-382. 1992
1992 Cytokine-Induced Immunoglobulin Production in Primary IgA NephropathyOregon Social Studies Journal.  20:611-617. 1992
1992 Familial IgA Nephropathy Associated With Bilateral Sensorineural DeafnessOregon Social Studies Journal.  19:592-596. 1992
1992 IgA-containing immune complexes after challenge with food antigens in patients with IgA nephropathyMol. Biol. Cell.  89:315-320. 1992
1992 Improved survival of primary cadaveric renal allografts in blacks with quadruple immunosuppressionTransplantation.  53:103-109. 1992
1992 Musculoskeletal Complications After Renal Transplantation: Pathogenesis and TreatmentOregon Social Studies Journal.  19:99-120. 1992
1992 ReplyOregon Social Studies Journal.  20:531. 1992
1992 The impact of the UNOS mandatory sharing policy on recipients of the black and white races-experience at a single renal transplant centerTransplantation.  53:770-774. 1992
1991 Rapid loss of vertebral mineral density after renal transplantationNew England Journal of Medicine.  325:544-550. 1991
1991 Are black living-related renal donors at greater long-term risk of renal complications than white donors?Transplantation Proceedings.  23:1328-1329. 1991
1991 Analysis of 22 years experience in living-related transplantation at the University of Alabama in Birmingham.Annals of Psychiatry and Mental Health.  179-191. 1991
1991 C4A deficiency and poor prognosis in patients with IgA nephropathyPeriodicum Biologorum.  36:1-5. 1991
1991 Effects of enalapril on erythrocytosis after renal transplantationThrombosis.  115:954-955. 1991
1991 Epstein-Barr virus Transformation of B Lymphocytes From IgA Nephropathy Patients and First-Degree Relatives Results in Increased Immunoglobulin Synthesis not Restricted to IgAOregon Social Studies Journal.  17:55-61. 1991
1991 IgA nephropathy in blacks: Studies of IgA2 allotypes and clinical courseKidney International.  39:1218-1224. 1991
1991 Long-term results of a controlled prospective study with transfusion of donor-specific bone marrow in 57 cadaveric renal allograft recipientsTransplantation.  51:70-75. 1991
1991 Macroscopic Hematuria and Proteinuria Preceding Renal IgA Deposition in Patients With IgA NephropathyOregon Social Studies Journal.  17:472-479. 1991
1991 OKT3 first-dose reaction: Association with T cell subsets and cytokine releaseKidney International.  39:141-148. 1991
1991 Role for specific complement phenotypes and deficiencies in the clinical expression of IgA nephropathyCurrent Opinion in Virology.  301:115-123. 1991
1991 Selective Elevation of Monomeric IgA1 in IgA Nephropathy Patients With Normal Renal FunctionOregon Social Studies Journal.  18:313-319. 1991
1990 C4B Deficiency in Two Siblings With IgA NephropathyOregon Social Studies Journal.  15:66-71. 1990
1990 Cyclosporine-induced changes in glomerular filtration rate and urea excretionElectronic Journal of Biotechnology.  88:497-502. 1990
1990 Cyclosporine-induced changes in glomerular filtration rate and urea excretionElectronic Journal of Biotechnology.  88:497-502. 1990
1990 Donor antigen-specific immunosuppression in cadaveric and living-related donor kidney allograft recipients.Annals of Psychiatry and Mental Health.  289-300. 1990
1990 J chain disease: A novel form of plasma cell dyscrasiaElectronic Journal of Biotechnology.  88:411-416. 1990
1990 Regional variation in C4 phenotype in patients with IgA nephropathyJournal of Pediatrics.  116. 1990
1989 NON-SPECIFIC MESANGIAL STAINING WITH ANTIBODIES AGAINST CYTOMEGALOVIRUS IN IMMUNOGLOBULIN-A NEPHROPATHYLancet.  333:129-131. 1989
1989 Non-specific mesangial staining with antibodies against cytomegalovirus in immunoglobulin-A nephropathyLancet.  1:129-131. 1989
1989 Successful renal allografts in recipients with a positive standard, DTE negative cross-matchTransplantation Proceedings.  21:746-747. 1989
1989 Successful renal allografts in recipients with crossmatch-positive, dithioerythritol-treated negative sera: Race, transplant history, and HLA-DR1 phenotypeTransplantation.  47:240-245. 1989
1989 Sustained high panel reactive antibody levels in highly sensitized patients: Significance of continued transfusionsTransplantation Proceedings.  21:771-772. 1989
1989 Use of cryopreserved donor bone marrow in cadaver kidney allograft recipientsTransplantation.  47:66-71. 1989
1988 A Comparison of OKT3 Monoclonal Antibody and Corticosteroids in the Treatment of Acute Renal Allograft RejectionOregon Social Studies Journal.  11:86-89. 1988
1988 Activation of Complement in IgA NephropathyOregon Social Studies Journal.  12:437-442. 1988
1988 Bilateral Cavernous Sinus Thrombosis due to MucormycosisHuman Pathology.  106:1089-1092. 1988
1988 Early graft loss in cyclosporine A-treated cadaveric renal allograft recipients receiving retransplants against previous mismatched HLA-A, -B, -DR donor antigensTransplantation Proceedings.  20:170-172. 1988
1988 Familial Clustering and Immunogenetic Aspects of IgA NephropathyOregon Social Studies Journal.  12:366-370. 1988
1988 IgA nephropathy, the most common glomerulonephritis worldwide. A neglected disease in the United States?Electronic Journal of Biotechnology.  84:129-132. 1988
1988 On the mechanism by which chloride corrects metabolic alkalosis in manElectronic Journal of Biotechnology.  84:449-458. 1988
1987 Genetic factors in primary IgA nephropathyNephrology Dialysis Transplantation.  2:134-142. 1987
1987 Morphologic and immunohistochemical observations in granulomatous glomerulonephritisOmega.  126:581-591. 1987
1987 A major gene model for the familial aggregation of plasma IgA concentrationJournal of Ethnopharmacology.  27:857-866. 1987
1987 Aberrant synthesis of antibodies directed at the Fab fragment of IgA in patients with IgA nephropathiesAntioxidants.  45:208-213. 1987
1987 Analysis of immunoglobulin heavy chain restriction fragment length polymorphisms in IgA nephropathy.Seminars in Nephrology.  7:306-310. 1987
1987 Antibodies directed at Fab of IgA in the sera of normal individuals and IgA nephropathy patients.Transplantation.  216 B:1537-1544. 1987
1987 Complement activation in IgA nephropathyKidney International.  31:1019-1023. 1987
1987 Complement phenotypes (C3 and C4) in IgA nephropathy.Transplantation.  216 B:1569-1575. 1987
1987 Detection of food antigen-specific IgA immune complexes in human sera.Transplantation.  216 A:813-820. 1987
1987 Fatal rhizopus infections in hemodialysis patients receiving deferoxamineThrombosis.  107:678-679. 1987
1987 IgA-associated renal diseases: immunochemical studies of IgA1 proteins, circulating immune complexes, and cellular interactions.Seminars in Nephrology.  7:332-335. 1987
1987 Immunogenetic markers as prognostic features in patients from Kentucky with IgA nephropathy.Seminars in Nephrology.  7:389-392. 1987
1987 Immunological studies of IgA nephropathy: familial and racial aspects.Transplantation.  216 B:1489-1498. 1987
1987 Influence of race on renal allograft survival in the pre- and postcyclosporine era.Annals of Psychiatry and Mental Health.  217-233. 1987
1987 Oxalosis in Bone Causing a Radiographical Mimicry of Renal OsteodystrophyOregon Social Studies Journal.  9:436-440. 1987
1987 Regionalization in hereditary IgA nephropathyJournal of Cybersecurity Education, Research, and Practice.  41:36-50. 1987
1987 Striking Elevation of Serum IgA, IgA-Containing Immune Complexes, and IgA Rheumatoid Factor in Clinically Silent Dermatitis HerpetiformisOregon Social Studies Journal.  10:378-384. 1987
1986 Aluminum-associated renal osteodystrophy.The Alabama journal of medical sciences.  23:414-419. 1986
1986 Aluminum-related bone disease in mild and advanced renal failure: Evidence for high prevalence and morbidity and studies on etiology and diagnosisMethods in Neurosciences.  6:275-283. 1986
1986 Circulating immune complexes and immunoglobulin A rheumatoid factor in patients with mesangial immunoglobulin A nephropathiesJournal of Clinical Investigation.  77:1931-1938. 1986
1986 IgA-associated renal diseases: Antibodies to environmental antigens in sera and deposition of immunoglobulins and antigens in glomeruliJournal of Clinical Immunology.  6:74-86. 1986
1985 Familial IgA NephropathyNew England Journal of Medicine.  313:186. 1985
1985 Familial IgA Nephropathy: Evidence of an Inherited Mechanism of DiseaseNew England Journal of Medicine.  312:202-208. 1985
1985 Focal Sclerosis of Hypertrophied Glomeruli in Solitary Functioning Kidneys of HumansOregon Social Studies Journal.  5:226-232. 1985
1985 The immunogenetics of IgA nephropathyPlasma Therapy and Transfusion Technology.  6:687-704. 1985
1984 Complement phenotypes in glomerulonephritis: Increased frequency of homozygous null C4 phenotypes in IgA nephropathy and Henoch-Schonlein purpuraKidney International.  26:855-860. 1984
1984 IgA Nephropathy: Presentation, Clinical Course, and Prognosis in Children and AdultsOregon Social Studies Journal.  4:192-200. 1984
1984 Increased frequency of C3 fast alleles in IgA nephropathyJournal Of Practical Global Business.  2:419-428. 1984
1983 Serum complement proteins in IgA nephropathyPeriodicum Biologorum.  20:251-258. 1983
1982 Partial H (β1H) deficiency and glomerulonephritis in two familiesJournal of Clinical Immunology.  2:110-117. 1982
1982 Renin and aldosterone responses to short-term NaCl or NaHCO3 loading in manJournal of Laboratory and Clinical Medicine.  100:261-268. 1982
1981 Properdin Deficiency with IgA NephropathyNew England Journal of Medicine.  305:1097. 1981

Chapter

Year Title Altmetric
2016 Heterogeneity of aberrant O-glycosylation of IgA1 in IgA nephropathy.  53-68. 2016
2015 IgA Nephropathy and Related Diseases.  2023-2038. 2015
2009 Clinicopathologic findings.  83-106. 2009

Research Overview

  • IgA nephropathy
    Kidney transplantation
  • Investigator On

  • Private Grant  awarded by CALLIDITAS THERAPEUTICS AB 2019 - 2026
  • Private Grant  awarded by RETROPHIN, INC. 2019 - 2024
  • Private Grant  awarded by VELOXIS PHARMACEUTICALS A/S 2019 - 2023
  • Private Grant  awarded by CSL BEHRING, LLC 2017 - 2022
  • APOL1 Long-Term Kidney Transplantation Outcomes Network (APOLLO) Clinical Center  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2019 - 2022
  • Private Grant  awarded by MALLINCKRODT, INC. 2017 - 2022
  • Novel Therapies to Modulate the Inflammatory Alloresponse in Renal Grafts  awarded by University of California, San Francisco 2014 - 2021
  • Private Grant  awarded by QUARK PHARMACEUTICALS, INC. 2015 - 2020
  • Private Grant  awarded by ALEXION PHARMACEUTICALS, INC. 2018 - 2020
  • Effects of Inhibiting Early Inflammation in Kidney Transplant Patients - Equipment  awarded by Mount Sinai School of Medicine 2015 - 2020
  • Abnormal STAT3 Signaling and Aberrant O-Glycosylation of IgA1 in IgA Nephropathy  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2015 - 2020
  • Elucidating IgA Nephropathy Through Genetic Studies of IgA1 Glycosylation  awarded by Columbia University 2014 - 2020
  • Analytical Tools for the Analysis of Clustered O-Glycans in Clinical Samples  awarded by National Institute of General Medical Sciences/NIH/DHHS 2016 - 2020
  • Genetics of IgA Nephropathy by Integrative Network-Based Association Studies  awarded by Columbia University 2015 - 2020
  • Genetic, Environmental & Histologic Basis for Kidney Disease Risk among Persons Living with HIV  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2018 - 2019
  • UAB Center for AIDS Research  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS 2014 - 2019
  • Molecular Basis of Pathogenicity of IgA1-containing Immune Complexes  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2012 - 2019
  • Aptamers-Based Arrays for Detection of Pathogenic IgA 1 O-Glycoforms in IgA Nephropathy  awarded by Columbia University 2016 - 2018
  • IgA Nephropathy: Interventions with Generation of Nephritogenic Immune Complexes  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2014 - 2018
  • Private Grant  awarded by ALEXION PHARMACEUTICALS, INC. 2014 - 2017
  • Preserving Renal Function & Protective Immunity via Anti-LFA-1-Based CNI Avoidance  awarded by Emory University 2009 - 2016
  • Analytical Tools for the Analysis of Clustered O-Glycans in Clinical Samples  awarded by National Institute of General Medical Sciences/NIH/DHHS 2011 - 2016
  • Private Grant  awarded by ANTHERA PHARMACEUTICALS, INC 2015 - 2016
  • Private Grant  awarded by Pfizer Pharmaceuticals 2013 - 2015
  • Elucidating IgA Nephropathy Through Genetic Studies of IgA1 Glycosylation  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2009 - 2014
  • New Animal Model for Studies of Mucosal Immunity and IgA Nephropathy  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2010 - 2013
  • Education And Training

  • Doctor of Medicine, Washington University/St. Louis 1975
  • University of Kentucky/Chandler Hospital, Internship 1976
  • University of Kentucky/Chandler Hospital, Residency 1978
  • University of Kentucky/Chandler Hospital, Postdoctoral Fellowship 1980
  • Full Name

  • Bruce Julian