Positions

Selected Publications

Academic Article

Year Title Altmetric
2019 Transfer of Functional Cargo in Exomeres 2019
2018 Effector CD4 T cells with progenitor potential mediate chronic intestinal inflammation 2018
2018 Sialylation of EGFR by the ST6Gal-I sialyltransferase promotes EGFR activation and resistance to gefitinib-mediated cell death 2018
2018 ST6Gal-I sialyltransferase promotes chemoresistance in pancreatic ductal adenocarcinoma by abrogating gemcitabine-mediated DNA damage 2018
2018 ST6Gal-I sialyltransferase promotes tumor necrosis factor (TNF)-mediated cancer cell survival via sialylation of the TNF receptor 1 (TNFR1) death receptor 2018
2018 The ST6Gal-I sialyltransferase protects tumor cells against hypoxia by enhancing HIF-1 signaling 2018
2017 Enhanced skin regeneration using a novel amniotic-derived tissue graft 2017
2017 The glycosyltransferase ST6Gal-I protects tumor cells against serum growth factor withdrawal by enhancing survival signaling and proliferative potential 2017
2016 The tumor-associated glycosyltransferase ST6Gal-I regulates stem cell transcription factors and confers a cancer stem cell phenotype 2016
2016 Taking cues from the extracellular matrix to design bone-mimetic regenerative scaffolds 2016
2016 Controlled and targeted release of antigens by intelligent shell for improving applicability of oral vaccines 2016
2015 Enhancement of the Regenerative Potential of Anorganic Bovine Bone Graft Utilizing a Polyglutamate-Modified BMP2 Peptide with Improved Binding to Calcium-Containing Materials 2015
2015 Using inositol as a biocompatible ligand for efficient transgene expression 2015
2015 Microporous dermal-mimetic electrospun scaffolds pre-seeded with fibroblasts promote tissue regeneration in full-thickness skin wounds 2015
2014 Comparing variable-length polyglutamate domains to anchor an osteoinductive collagen-mimetic peptide to diverse bone grafting materials 2014
2014 Microporous dermal-like electrospun scaffolds promote accelerated skin regeneration 2014
2014 Tunable delivery of bioactive peptides from hydroxyapatite biomaterials and allograft bone using variable-length polyglutamate domains 2014
2013 Targeting protein kinase CK2 suppresses prosurvival signaling pathways and growth of glioblastoma 2013
2013 ST6Gal-I sialyltransferase confers cisplatin resistance in ovarian tumor cells 2013
2013 ST6Gal-I protein expression is upregulated in human epithelial tumors and correlates with stem cell markers in normal tissues and colon cancer cell lines 2013
2013 Engineering nanocages with polyglutamate domains for coupling to hydroxyapatite biomaterials and allograft bone 2013
2013 Polyglutamate directed coupling of bioactive peptides for the delivery of osteoinductive signals on allograft bone 2013
2012 Regulation of the metastatic cell phenotype by sialylated glycans 2012
2012 Delivery of platelet-derived growth factor as a chemotactic factor for mesenchymal stem cells by bone-mimetic electrospun scaffolds 2012
2012 Increasing the pore sizes of bone-mimetic electrospun scaffolds comprised of polycaprolactone, collagen I and hydroxyapatite to enhance cell infiltration 2012
2011 Nanocomposite scaffolds based on electrospun polycaprolactone/modified CNF/nanohydroxyapatite by electrophoretic deposition 2011
2011 ST6Gal-I regulates macrophage apoptosis via α2-6 sialylation of the TNFR1 death receptor 2011
2011 Sialylation of the Fas death receptor by St6Gal-I provides protection against Fas-mediated apoptosis in colon carcinoma cells 2011
2011 Advantages of RGD peptides for directing cell association with biomaterials 2011
2011 Engineering an antiplatelet adhesion layer on an electrospun scaffold using porcine endothelial progenitor cells 2011
2011 Emerging role of α2,6-sialic acid as a negative regulator of galectin binding and function 2011
2011 Mesenchymal stem cell responses to bone-mimetic electrospun matrices composed of polycaprolactone, collagen I and nanoparticulate hydroxyapatite 2011
2010 Enhancement of peptide coupling to hydroxyapatite and implant osseointegration through collagen mimetic peptide modified with a polyglutamate domain 2010
2010 An in vitro regenerated functional human endothelium on a nanofibrous electrospun scaffold 2010
2009 Osteogenic differentiation of human mesenchymal stem cells directed by extracellular matrix-mimicking ligands in a biomimetic self-assembled peptide amphiphile nanomatrix 2009
2009 The effect of collagen I mimetic peptides on mesenchymal stem cell adhesion and differentiation, and on bone formation at hydroxyapatite surfaces 2009
2008 Comparison of mesenchymal stem cell and osteosarcoma cell adhesion to hydroxyapatite 2008
2008 Effect of altered glycosylation on the structure of the I-like domain of β1 integrin: A molecular dynamics study 2008
2008 Working group report: The roles of glycans in hemostasis, inflammation and vascular biology 2008
2008 ST6Gal-I expression in ovarian cancer cells promotes an invasive phenotype by altering integrin glycosylation and function. 2008
2008 Tumor cell migration and invasion are regulated by expression of variant integrin glycoforms 2008
2008 Proteolytic shedding of ST6Gal-I by BACE1 regulates the glycosylation and function of α4β1 integrins 2008
2008 Sialylation of β1 integrins blocks cell adhesion to galectin-3 and protects cells against galectin-3-induced apoptosis 2008
2008 Mesenchymal stem cell interaction with ultra-smooth nanostructured diamond for wear-resistant orthopaedic implants 2008
2008 The effect of RGD peptides on osseointegration of hydroxyapatite biomaterials 2008
2008 Low temperature induces the delivery of mature and immature CFTR to the plasma membrane 2008
2007 Identification of a HoxA10 activation domain necessary for transcription of the gene encoding β3 integrin during myeloid differentiation 2007
2007 The effect of adsorbed serum proteins, RGD and proteoglycan-binding peptides on the adhesion of mesenchymal stem cells to hydroxyapatite 2007
2006 Osteoblast adhesion and matrix mineralization on sol-gel-derived titanium oxide 2006
2006 Mesenchymal stem cell adhesion and spreading on microwave plasma-nitrided titanium alloy 2006
2005 The effect of the addition of a polyglutamate motif to RGD on peptide tethering to hydroxyapatite and the promotion of mesenchymal stem cell adhesion 2005
2005 A protein kinase C/Ras/ERK signaling pathway activates myeloid fibronectin receptors by altering β1 integrin sialylation 2005
2005 Hypersialylation of β 1 integrins, observed in colon adenocarcinoma, may contribute to cancer progression by up-regulating cell motility 2005
2005 Erratum: Primary human marrow stromal cells and Saos-2 osteosarcoma cells use different mechanisms to adhere to hydroxylapatite (Journal of Biomedical Materials Research - Part A (2004) 68A, 2 (273-285) DOI: 10.1002/jbm.a.20043) 2005
2005 Regulation of mesenchymal stem cell attachment and spreading on hydroxyapatite by RGD peptides and adsorbed serum proteins 2005
2004 Mesenchymal stem cell adhesion and spreading on nanostructured biomaterials 2004
2004 Variant glycosylation: An underappreciated regulatory mechanism for β1 integrins 2004
2004 Primary human marrow stromal cells and Saos-2 osteosarcoma cells use different mechanisms to adhere to hydroxylapatite 2004
2003 Ras oncogene directs expression of a differentially sialylated, functionally altered β1 integrin 2003
2002 Hyposialylation of integrins stimulates the activity of myeloid fibronectin receptors 2002
2001 TGF-β1 up-regulates paxillin protein expression in malignant astrocytoma cells: Requirement for a fibronectin substrate 2001
2001 Hydroxylapatite binds more serum proteins, purified integrins, and osteoblast precursor cells than titanium or steel 2001
1999 Steps in integrin beta1-chain glycosylation mediated by TGFbeta1 signaling through Ras. 1999
1999 Steps in integrin β1-chain glycosylation mediated by TGFβ1 signaling through ras 1999
1997 Adhesion of fibroblasts to fibronectin stimulates both serine and tyrosine phosphorylation of paxillin 1997
1995 Affinity purification of hydra glutathione bindings proteins. [FEBS Letters 354 (1994) 320-324] (PII:0014-5793(94)01154-0) 1995
1995 Characterization of tyrosine phosphorylation of paxillin in vitro by focal adhesion kinase 1995
1994 Signal transduction for taurocholic acid in the olfactory system of atlantic salmon 1994
1994 Affinity purification of Hydra glutathione binding proteins 1994
1992 Chemoreception in hydra: specific binding of glutathione to a membrane fraction 1992
1992 Partial Characterization and Detergent Solubilization of the Putative Glutathione Chemoreceptor from Hydra 1992
1991 Chemoreception in Hydra vulgaris (attenuata): initial characterization of two distinct binding sites for l-glutamic acid 1991

Principal Investigator On

  • Glycosylation-dependent Mechanisms Regulating Ovarian Tumor cell Phenotype  awarded by National Cancer Institute/NIH/DHHS 2019 - 2024
  • Sialylation-dependent Mechanisms Driving Pancreatic Cancer Progression  awarded by National Cancer Institute/NIH/DHHS 2018 - 2023
  • Research Collaboration with University of Copenhagen  awarded by University of Copenhagen 2019 - 2022
  • Tunable Co-Delivery of VEGF and BMP2 Mimetic Peptides to Enhance Bone Regeneration  awarded by National Institute of Dental and Craniofacial Research/NIH/DHHS 2018 - 2020
  • Coupling Osteoinductive Factors to Graft Materials to Promote Osteoregeneration  awarded by National Institute of Dental and Craniofacial Research/NIH/DHHS 2014 - 2019
  • Novel Mechanism of TNFR1 Regulation in Macrophage Apoptosis and Atherogenesis  awarded by American Heart Association 2017 - 2018
  • Glycosylation-Dependent Mechanisms Regulating Ovarian Tumor Cell Survival  awarded by National Institute of General Medical Sciences/NIH/DHHS 2014 - 2018
  • Glycan Control of Stem Cell-Associated Pathways in Pancreatic Cancer  awarded by National Cancer Institute/NIH/DHHS 2015 - 2017
  • Glycosylation-Dependent Control of TNFR1 Signaling in Macrophage Survival  awarded by American Heart Association (Southeast Affiliate) 2014 - 2016
  • UAB Skin Disease Research Center - P&F 20  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS 2011 - 2014
  • Private Grant  awarded by NUTECH MEDICAL, INC 2014
  • TNFR1 Death Receptor Glycosylation in Macrophage Apoptosis  awarded by American Heart Association (Southeast Affiliate) 2011 - 2014
  • Role of Receptor Sialylation in the Ovarian Tumor Cell Phenotype  awarded by DOD - ARMY MEDICAL RESEARCH ACQUISITION ACTIVITY 2011 - 2014
  • Targeted Delivery of Osteoinductive Molecules to Biologic HA in Bone Grafts  awarded by National Institute of Dental and Craniofacial Research/NIH/DHHS 2012 - 2014
  • Novel Method for Anchoring Osteoinductive Factors to Bone Graft Materials to Enhance Osseointegration  awarded by OSSEOINTEGRATION FOUNDATION 2012 - 2013
  • Regulation of Beta1 Integrin Glycosylation by Ras  awarded by National Cancer Institute/NIH/DHHS 2007 - 2013
  • Enhanced Coupling of Bone Regenerative Peptides to Hydroxyapatite-Containing Biomaterials  awarded by National Institute of Dental and Craniofacial Research/NIH/DHHS 2011 - 2013
  • Rheumatic Diseases Core Center: Pilot Project - P & F 5  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS 2010 - 2012
  • Role of Fas Glycoforms in Macrophage Apoptosis  awarded by American Heart Association 2010 - 2012
  • Functionalizing Hydroxyapatite with Proadhesive Peptides  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS 2005 - 2011
  • Role of Sialylation in Macrophage Apoptosis  awarded by American Heart Association (Southeast Affiliate) 2009 - 2011
  • Cell and Molecular Analysis of Biomaterials Core  awarded by UNIVERSITY OF ALABAMA HEALTH SERVICES FOUNDATION 2007 - 2011
  • Teaching Activities

  • BME799 - Dissertation Research (Fall Term 2019) 2019
  • BME799 - Dissertation Research (Summer Term 2019) 2019
  • BME799 - Dissertation Research (Spring Term 2019) 2019
  • BME799 - Dissertation Research (Fall Term 2018) 2018
  • BME799 - Dissertation Research (Summer Term 2018) 2018
  • BME799 - Dissertation Research (Spring Term 2018) 2018
  • BME798 - Non-Dissertation Research (Fall Term 2017) 2017
  • BME798 - Non-Dissertation Research (Summer Term 2017) 2017
  • BME798 - Non-Dissertation Research (Spring Term 2017) 2017
  • BME798 - Non-Dissertation Research (Summer Term 2016) 2016
  • BME798 - Non-Dissertation Research (Spring Term 2016) 2016
  • BME798 - Non-Dissertation Research (Fall Term 2015) 2015
  • BME798 - Non-Dissertation Research (Summer Term 2015) 2015
  • BME798 - Non-Dissertation Research (Spring Term 2015) 2015
  • BME798 - Non-Dissertation Research (Fall Term 2014) 2014
  • BME799 - Dissertation Research (Spring Term 2013) 2013
  • BME799 - Dissertation Research (Fall Term 2012) 2012
  • BME799 - Dissertation Research (Summer Term 2012) 2012
  • BME799 - Dissertation Research (Spring Term 2012) 2012
  • BME798 - Non-Dissertation Research (Fall Term 2011) 2011
  • BME798 - Non-Dissertation Research (Summer Term 2011) 2011
  • BME798 - Non-Dissertation Research (Spring Term 2011) 2011
  • BME798 - Non-Dissertation Research (Fall Term 2010) 2010
  • BME699 - Masters Thesis Research (Summer Term 2010) 2010
  • BME699 - Masters Thesis Research (Spring Term 2010) 2010
  • BME698 - Non-Thesis Research (Fall Term 2009) 2009
  • BME698 - Non-Thesis Research (Summer Term 2009) 2009
  • BME698 - Non-Thesis Research (Spring Term 2009) 2009
  • BME698 - Non-Thesis Research (Fall Term 2008) 2008
  • BME799 - Dissertation Research (Fall Term 2008) 2008
  • PHY790 - Selected Topics Physiology I (Fall Term 2008) 2008
  • BME799 - Dissertation Research (Summer Term 2008) 2008
  • BME799 - Dissertation Research (Spring Term 2008) 2008
  • BME799 - Dissertation Research (Fall Term 2007) 2007
  • Full Name

  • Susan Bellis