Positions

Selected Publications

Academic Article

Year Title Altmetric
2019 Spatial distribution of marker gene activity in the mouse lung during alveolarization.Data in Brief.  22:365-372. 2019
2019 Airway Microbiome and Development of Bronchopulmonary Dysplasia in Preterm Infants: A Systematic Review.Journal of Pediatrics.  204:126-133.e2. 2019
2019 Behavioral Deficits at 18-22 Months of Age Are Associated with Early Cerebellar Injury and Cognitive and Language Performance in Children Born Extremely Preterm.Journal of Pediatrics.  204:148-156.e4. 2019
2019 The impact of fluid balance on outcomes in critically ill near-term/term neonates: a report from the AWAKEN study group.Pediatric Research.  85:79-85. 2019
2019 Weaning of Moderately Preterm Infants from the Incubator to the Crib: A Randomized Clinical Trial.Journal of Pediatrics.  204:96-102.e4. 2019
2018 Late onset neonatal acute kidney injury: results from the AWAKEN Study.Pediatric Research2018
2018 Optimizing the AKI definition during first postnatal week using Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates (AWAKEN) cohort.Pediatric Research2018
2018 Extracellular matrix in lung development, homeostasis and disease.Collagen and related research.  73:77-104. 2018
2018 Genomics, microbiomics, proteomics, and metabolomics in bronchopulmonary dysplasia.Seminars in Perinatology.  42:425-431. 2018
2018 Mechanisms of Ventilator-induced Lung Injury: Is the Elafin in the Room?American Journal of Respiratory Cell and Molecular Biology.  59:531-532. 2018
2018 Iloprost attenuates hyperoxia-mediated impairment of lung development in newborn mice.AJP - Lung Cellular and Molecular Physiology.  315:L535-L544. 2018
2018 Environmental or Nasal Cannula Supplemental Oxygen for Preterm Infants: A Randomized Cross-Over Trial.Journal of Pediatrics.  200:98-103. 2018
2018 Extreme Preterm Infant Rates of Overweight and Obesity at School Age in the SUPPORT Neuroimaging and Neurodevelopmental Outcomes Cohort.Journal of Pediatrics.  200:132-139.e3. 2018
2018 Early Airway Microbial Metagenomic and Metabolomic Signatures are Associated with Development of Severe Bronchopulmonary Dysplasia.AJP - Lung Cellular and Molecular Physiology2018
2018 Incidence of neonatal hypertension from a large multicenter study [Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates-AWAKEN].Pediatric Research.  84:279-289. 2018
2018 Supraphysiological Levels of Oxygen Exposure During the Neonatal Period Impairs Signaling Pathways Required for Learning and Memory.Scientific Reports.  8:9914. 2018
2018 Preterm Neuroimaging and School-Age Cognitive Outcomes.Pediatrics.  142. 2018
2018 The Impact of Maternal Antibiotics on Neonatal Disease.Journal of Pediatrics.  197:97-103.e3. 2018
2018 Reply to Shah et al.: Mitochondrial Dysfunction in Bronchopulmonary Dysplasia.American Journal of Respiratory and Critical Care Medicine.  197:1363-1364. 2018
2018 Neurodevelopmental Impairment Among Extremely Preterm Infants in the Neonatal Research Network.Pediatrics.  141. 2018
2018 Surgical necrotizing enterocolitis in extremely premature neonates is associated with genetic variations in an intergenic region of chromosome 8.Pediatric Research.  83:943-953. 2018
2018 Antecedents and Outcomes of Abnormal Cranial Imaging in Moderately Preterm Infants.Journal of Pediatrics.  195:66-72.e3. 2018
2018 Delivery Room Resuscitation and Short-Term Outcomes in Moderately Preterm Infants.Journal of Pediatrics.  195:33-38.e2. 2018
2018 Outcome of Preterm Infants with Transient Cystic Periventricular Leukomalacia on Serial Cranial Imaging Up to Term Equivalent Age.Journal of Pediatrics.  195:59-65.e3. 2018
2018 iDREM: Interactive visualization of dynamic regulatory networks.PLoS Computational Biology.  14:e1006019. 2018
2018 Exosomal microRNA predicts and protects against severe bronchopulmonary dysplasia in extremely premature infants.JCI insight.  3. 2018
2018 Effect of Therapeutic Hypothermia Initiated after 6 Hours of Age on Death or Disability among Newborns with Hypoxic-Ischemic Encephalopathy: A Randomized Clinical TrialObstetrical and Gynecological Survey.  73:141-143. 2018
2018 MicroRNA-145 Antagonism Reverses TGF-β Inhibition of F508del CFTR Correction in Airway Epithelia.American Journal of Respiratory and Critical Care Medicine.  197:632-643. 2018
2018 Kangaroo mother care for the prevention of neonatal hypothermia: a randomised controlled trial in term neonates.Archives of Disease in Childhood.  103:492-497. 2018
2018 Is It Necessary to Heat and Humidify Respiratory Gases for Resuscitation in Preterm Infants?Journal of Pediatrics.  193:10-11. 2018
2018 A Shared Pattern of β-Catenin Activation in Bronchopulmonary Dysplasia and Idiopathic Pulmonary Fibrosis.American Journal of Pathology.  188:853-862. 2018
2018 Admission Temperature and Associated Mortality and Morbidity among Moderately and Extremely Preterm Infants.Journal of Pediatrics.  192:53-59.e2. 2018
2018 Dose-Response Effects of Early Vitamin D Supplementation on Neurodevelopmental and Respiratory Outcomes of Extremely Preterm Infants at 2 Years of Age: A Randomized Trial.Biology of the Neonate.  113:256-262. 2018
2018 Neurodevelopmental and Behavioral Outcomes in Extremely Premature Neonates With Ventriculomegaly in the Absence of Periventricular-Intraventricular Hemorrhage.JAMA Pediatrics.  172:32-42. 2018
2017 Mortality and pulmonary outcomes of extremely preterm infants exposed to antenatal corticosteroids.American Journal of Obstetrics and Gynecology.  218:130.e1-130.e13. 2017
2017 Incidence and outcomes of neonatal acute kidney injury (AWAKEN): a multicentre, multinational, observational cohort study.Lancet Child and Adolescent Health.  1:184-194. 2017
2017 LungMAP: The Molecular Atlas of Lung Development Program.AJP - Lung Cellular and Molecular Physiology.  313:L733-L740. 2017
2017 Outcomes of Preterm Infants following Discussions about Withdrawal or Withholding of Life Support.Journal of Pediatrics.  190:118-123.e4. 2017
2017 Hyperoxia causes miR-34a-mediated injury via angiopoietin-1 in neonatal lungs.Nature Communications.  8:1173. 2017
2017 Exposure of neonatal mice to bromine impairs their alveolar development and lung function.AJP - Lung Cellular and Molecular Physiology.  314:L137-L143. 2017
2017 Effect of Depth and Duration of Cooling on Death or Disability at Age 18 Months Among Neonates With Hypoxic-Ischemic Encephalopathy: A Randomized Clinical Trial.Journal of the American Medical Association.  318:57-67. 2017
2017 Association between Use of Prophylactic Indomethacin and the Risk for Bronchopulmonary Dysplasia in Extremely Preterm Infants.Journal of Pediatrics.  186:34-40.e2. 2017
2017 Developing a neonatal acute kidney injury research definition: a report from the NIDDK neonatal AKI workshop.Pediatric Research.  82:569-573. 2017
2017 Mechanisms and Treatment of Halogen Inhalation-Induced Pulmonary and Systemic Injuries in Pregnant Mice.Hypertension.  70:390-400. 2017
2017 Markers of Successful Extubation in Extremely Preterm Infants, and Morbidity After Failed Extubation.Journal of Pediatrics.  189:113-119.e2. 2017
2017 Vascular Endothelial Mitochondrial Function Predicts Death or Pulmonary Outcomes in Preterm Infants.American Journal of Respiratory and Critical Care Medicine.  196:1040-1049. 2017
2017 Vitamin A and retinoic acid combination attenuates neonatal hyperoxia-induced neurobehavioral impairment in adult mice.Neurobiology of Learning and Memory.  141:209-216. 2017
2017 A functional ATG16L1 (T300A) variant is associated with necrotizing enterocolitis in premature infants.Pediatric Research.  81:582-588. 2017
2017 Feasibility of Mid-Frequency Ventilation Among Infants With Respiratory Distress Syndrome.Respiratory Care.  62:481-488. 2017
2017 Survival and Neurodevelopmental Outcomes among Periviable Infants.New England Journal of Medicine.  376:617-628. 2017
2017 Selecting the most appropriate time points to profile in high-throughput studies.eLife.  6. 2017
2017 Milrinone in congenital diaphragmatic hernia - a randomized pilot trial: study protocol, review of literature and survey of current practices.Maternal Health, Neonatology and Perinatology.  3:27. 2017
2017 Short versus Extended Duration of Trophic Feeding to Reduce Time to Achieve Full Enteral Feeding in Extremely Preterm Infants: An Observational Study.Biology of the Neonate.  112:211-216. 2017
2016 Spatially-Resolved Proteomics: Rapid Quantitative Analysis of Laser Capture Microdissected Alveolar Tissue Samples.Scientific Reports.  6:39223. 2016
2016 Cellular and humoral biomarkers of Bronchopulmonary Dysplasia.Early Human Development.  105:35-39. 2016
2016 Biomarkers associated with bronchopulmonary dysplasia/mortality in premature infants.Pediatric Research.  81:519-525. 2016
2016 Effect of Prenatal versus Postnatal Vitamin D Deficiency on Pulmonary Structure and Function in Mice.American Journal of Respiratory Cell and Molecular Biology.  56:383-392. 2016
2016 Maternal and neonatal mortality: time to act.Jornal de Pediatria.  92:543-545. 2016
2016 Patterns of Oxygenation, Mortality, and Growth Status in the Surfactant Positive Pressure and Oxygen Trial Cohort.Journal of Pediatrics.  186:49-56.e1. 2016
2016 Adjunctive Azithromycin Prophylaxis for Cesarean Delivery.New England Journal of Medicine.  375:1231-1241. 2016
2016 Searching for better animal models of BPD: a perspective.AJP - Lung Cellular and Molecular Physiology.  311:L924-L927. 2016
2016 Ureaplasma infection-mediated release of matrix metalloproteinase-9 and PGP: a novel mechanism of preterm rupture of membranes and chorioamnionitis.Pediatric Research.  81:75-79. 2016
2016 Growth Outcomes of Preterm Infants Exposed to Different Oxygen Saturation Target Ranges from Birth.Journal of Pediatrics.  176:62-68.e4. 2016
2016 Impact of Optimized Breastfeeding on the Costs of Necrotizing Enterocolitis in Extremely Low Birthweight Infants.Journal of Pediatrics.  175:100-105.e2. 2016
2016 Acute Kidney Injury Urine Biomarkers in Very Low-Birth-Weight Infants.Clinical Journal of the American Society of Nephrology.  11:1527-1535. 2016
2016 Advantages of Bayesian monitoring methods in deciding whether and when to stop a clinical trial: an example of a neonatal cooling trial.Trials.  17:335. 2016
2016 A Comparison of 3 Vitamin D Dosing Regimens in Extremely Preterm Infants: A Randomized Controlled Trial.Journal of Pediatrics.  174:132-138.e1. 2016
2016 Blood Cytokine Profiles Associated with Distinct Patterns of Bronchopulmonary Dysplasia among Extremely Low Birth Weight Infants.Journal of Pediatrics.  174:45-51.e5. 2016
2016 Challenges, priorities and novel therapies for hypoxemic respiratory failure and pulmonary hypertension in the neonate.Journal of Perinatology.  36 Suppl 2:S32-S36. 2016
2016 Management of hypoxemic respiratory failure and pulmonary hypertension in preterm infants.Journal of Perinatology.  36 Suppl 2:S20-S27. 2016
2016 Setting research priorities to improve global newborn health and prevent stillbirths by 2025.Journal of Global Health.  6:010508. 2016
2016 Acute changes in fluid status affect the incidence, associative clinical outcomes, and urine biomarker performance in premature infants with acute kidney injury.Pediatric Nephrology.  31:843-851. 2016
2016 Pathogenetics of alveolar capillary dysplasia with misalignment of pulmonary veins.Human Genetics.  135:569-586. 2016
2016 Hyperoxia Induces Intracellular Acidification in Neonatal Mouse Lung Fibroblasts: Real-Time Investigation Using Plasmonically Enhanced Raman Spectroscopy.Journal of the American Chemical Society.  138:3779-3788. 2016
2016 Regulation of alveolar septation by microRNA-489.AJP - Lung Cellular and Molecular Physiology.  310:L476-L487. 2016
2016 Gestational age and birthweight for risk assessment of neurodevelopmental impairment or death in extremely preterm infants.Archives of Disease in Childhood. Fetal and Neonatal Edition2016
2016 Endothelial Cell Bioenergetics and Mitochondrial DNA Damage Differ in Humans Having African or West Eurasian Maternal Ancestry.Circulation: Cardiovascular Genetics.  9:26-36. 2016
2016 Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates: Design of a Retrospective Cohort Study.Frontiers in Pediatrics.  4:68. 2016
2016 Association of Chorioamnionitis with Aberrant Neonatal Gut Colonization and Adverse Clinical Outcomes.PLoS ONE.  11:e0162734. 2016
2016 TLR4 regulates pulmonary vascular homeostasis and remodeling via redox signaling.Frontiers in Bioscience.  21:397-409. 2016
2016 The Airway Microbiome at Birth.Scientific Reports.  6:31023. 2016
2015 Biomarkers, Early Diagnosis, and Clinical Predictors of Bronchopulmonary Dysplasia.Clinics in Perinatology.  42:739-754. 2015
2015 Genes and environment in neonatal intraventricular hemorrhage.Seminars in Perinatology.  39:592-603. 2015
2015 Genetic predisposition to bronchopulmonary dysplasia.Seminars in Perinatology.  39:584-591. 2015
2015 High-Magnitude and/or High-Frequency Mechanical Strain Promotes Peripapillary Scleral Myofibroblast Differentiation.Investigative Ophthalmology & Visual Science.  56:7821-7830. 2015
2015 Impact of gestational age, sex, and postnatal age on urine biomarkers in premature neonates.Pediatric Nephrology.  30:2037-2044. 2015
2015 Seasonal Variation in Solar Ultra Violet Radiation and Early Mortality in Extremely Preterm Infants.American Journal of Perinatology.  32:1273-1276. 2015
2015 Serum eotaxin-1 is increased in extremely-low-birth-weight infants with bronchopulmonary dysplasia or death.Pediatric Research.  78:498-504. 2015
2015 Acute kidney injury in neonatesPediatrics in Review.  16:e586-e592. 2015
2015 Addendum: Kong, M.Y.; Whitley, R.J.; Peng, N.; Oster, R.; Schoeb, T.R.; Sullender, W.; Ambalavanan, N.; Clancy, J.P.; Gaggar, A.; Blalock J.E. Matrix Metalloproteinase-9 Mediates RSV Infection in Vitro and in Vivo. Viruses 2015, 30, 7, 4230–4253.Viruses.  7:5609. 2015
2015 A Nitric Oxide-Releasing Self-Assembled Peptide Amphiphile Nanomatrix for Improving the Biocompatibility of Microporous Hollow Fibers.ASAIO Journal.  61:589-595. 2015
2015 Acute kidney injury is associated with bronchopulmonary dysplasia/mortality in premature infants.Pediatric Nephrology.  30:1511-1518. 2015
2015 Array comparative genomic hybridisation testing in CHD.Cardiology in the Young.  25:1155-1172. 2015
2015 Respiratory syncytial virus infection increases chlorine-induced airway hyperresponsiveness.AJP - Lung Cellular and Molecular Physiology.  309:L205-L210. 2015
2015 Matrix Metalloproteinase-9 Mediates RSV Infection in Vitro and in Vivo.Viruses.  7:4230-4253. 2015
2015 Alterations in gene expression and DNA methylation during murine and human lung alveolar septation.American Journal of Respiratory Cell and Molecular Biology.  53:60-73. 2015
2015 Noninvasive imaging of experimental lung fibrosis.American Journal of Respiratory Cell and Molecular Biology.  53:8-13. 2015
2015 Developmental outcomes of extremely preterm infants born to adolescent mothers.Pediatrics.  135:1082-1092. 2015
2015 Genetic polymorphisms of heme-oxygenase 1 (HO-1) may impact on acute kidney injury, bronchopulmonary dysplasia, and mortality in premature infants.Pediatric Research.  77:793-798. 2015
2015 A randomised trial of re-feeding gastric residuals in preterm infants.Archives of Disease in Childhood. Fetal and Neonatal Edition.  100:F224-F228. 2015
2015 Early exposure to hyperoxia or hypoxia adversely impacts cardiopulmonary development.American Journal of Respiratory Cell and Molecular Biology.  52:594-602. 2015
2015 Disseminated Ureaplasma infection as a cause of fatal hyperammonemia in humans.Science Translational Medicine.  7:284re3. 2015
2015 Integrated genomic analyses in bronchopulmonary dysplasia.Journal of Pediatrics.  166:531-7.e13. 2015
2015 PaCO2 in surfactant, positive pressure, and oxygenation randomised trial (SUPPORT).Archives of Disease in Childhood. Fetal and Neonatal Edition.  100:F145-F149. 2015
2015 Causes and timing of death in extremely premature infants from 2000 through 2011.New England Journal of Medicine.  372:331-340. 2015
2015 Center Variation in Intestinal Microbiota Prior to Late-Onset Sepsis in Preterm Infants.PLoS ONE.  10:e0130604. 2015
2015 Pharmacokinetics, microbial response, and pulmonary outcomes of multidose intravenous azithromycin in preterm infants at risk for Ureaplasma respiratory colonization.Antimicrobial Agents and Chemotherapy.  59:570-578. 2015
2014 Effect of depth and duration of cooling on deaths in the NICU among neonates with hypoxic ischemic encephalopathy: a randomized clinical trial.Journal of the American Medical Association.  312:2629-2639. 2014
2014 Inhaled PGE1 in neonates with hypoxemic respiratory failure: two pilot feasibility randomized clinical trials.Trials.  15:486. 2014
2014 Prophylactic indomethacin and intestinal perforation in extremely low birth weight infants.Pediatrics.  134:e1369-e1377. 2014
2014 The value of Pa(CO2) in relation to outcome in congenital diaphragmatic hernia.American Journal of Perinatology.  31:939-946. 2014
2014 Outcomes of extremely low birthweight infants with acidosis at birth.Archives of Disease in Childhood. Fetal and Neonatal Edition.  99:F263-F268. 2014
2014 Histone deacetylase inhibition promotes fibroblast apoptosis and ameliorates pulmonary fibrosis in mice.European Respiratory Journal.  43:1448-1458. 2014
2014 Pulmonary matrix metalloproteinase-9 activity in mechanically ventilated children with respiratory syncytial virus.European Respiratory Journal.  43:1086-1096. 2014
2014 Outcomes of extremely preterm infants following severe intracranial hemorrhage.Journal of Perinatology.  34:203-208. 2014
2014 Pulmonary hypertension in bronchopulmonary dysplasia.Teratology -Philadelphia-.  100:240-246. 2014
2014 Wiping versus suction to clear neonatal airways at birth - Authors' reply.Lancet.  383:695-696. 2014
2014 Inflammatory signals that regulate intestinal epithelial renewal, differentiation, migration and cell death: Implications for necrotizing enterocolitis.Pathophysiology.  21:67-80. 2014
2014 Mortality and morbidity of VLBW infants with trisomy 13 or trisomy 18.Pediatrics.  133:226-235. 2014
2014 Authors' replyLancet.  383:695-696. 2014
2014 Intestinal microbiota of preterm infants differ over time and between hospitals.Microbiome.  2:36. 2014
2014 Long-term respiratory morbidities after bronchopulmonary dysplasia despite current therapies.Journal of Pediatrics.  164:12-13. 2014
2013 Impact of early surfactant and inhaled nitric oxide therapies on outcomes in term/late preterm neonates with moderate hypoxic respiratory failure.Journal of Perinatology.  33:944-949. 2013
2013 In utero exposure to second-hand smoke aggravates the response to ovalbumin in adult mice.American Journal of Respiratory Cell and Molecular Biology.  49:1102-1109. 2013
2013 Characteristics of extremely low-birth-weight infant survivors with unimpaired outcomes at 30 months of age.Journal of Perinatology.  33:800-805. 2013
2013 Reconstructing dynamic microRNA-regulated interaction networks.Proceedings of the National Academy of Sciences.  110:15686-15691. 2013
2013 Histological characteristics of the fetal inflammatory response associated with neurodevelopmental impairment and death in extremely preterm infants.Journal of Pediatrics.  163:652-7.e1-2. 2013
2013 Randomized trial of plastic bags to prevent term neonatal hypothermia in a resource-poor setting.Pediatrics.  132:e656-e661. 2013
2013 Erratum: Myofibroblast differentiation and enhanced Tgf-B signaling in cystic fibrosis lung disease (PLoS ONE (2013) 8 (8))PLoS ONE.  8. 2013
2013 Oronasopharyngeal suction versus wiping of the mouth and nose at birth: a randomised equivalency trial.Lancet.  382:326-330. 2013
2013 Individual and center-level factors affecting mortality among extremely low birth weight infants.Pediatrics.  132:e175-e184. 2013
2013 VARA attenuates hyperoxia-induced impaired alveolar development and lung function in newborn mice.AJP - Lung Cellular and Molecular Physiology.  304:L803-L812. 2013
2013 Extremely low birth weight and infant mortality rates in the United States.Pediatrics.  131:855-860. 2013
2013 Fluid overload and mortality are associated with acute kidney injury in sick near-term/term neonate.Pediatric Nephrology.  28:661-666. 2013
2013 Randomized trial of early developmental intervention on outcomes in children after birth asphyxia in developing countries.Journal of Pediatrics.  162:705-712.e3. 2013
2013 Feeding practices and necrotizing enterocolitis.Clinics in Perinatology.  40:1-10. 2013
2013 Systems biology of lung development and regeneration: current knowledge and recommendations for future research.Wiley Interdisciplinary Reviews: Systems Biology and Medicine.  5:125-133. 2013
2013 Neurodevelopmental impairment following neonatal hyperoxia in the mouse.Neurobiology of Disease.  50:69-75. 2013
2013 Titanium oxide nanoparticle instillation induces inflammation and inhibits lung development in mice.AJP - Lung Cellular and Molecular Physiology.  304:L152-L161. 2013
2013 Nano-TiO₂ particles impair adhesion of airway epithelial cells to fibronectin.Respiratory Physiology and Neurobiology.  185:454-460. 2013
2013 Myofibroblast differentiation and enhanced TGF-B signaling in cystic fibrosis lung disease.PLoS ONE.  8:e70196. 2013
2012 In utero exposure to second-hand smoke aggravates adult responses to irritants: adult second-hand smoke.American Journal of Respiratory Cell and Molecular Biology.  47:843-851. 2012
2012 Cytokines and posthemorrhagic ventricular dilation in premature infants.American Journal of Perinatology.  29:731-740. 2012
2012 Altered DNA methylation profile in idiopathic pulmonary fibrosis.American Journal of Respiratory and Critical Care Medicine.  186:525-535. 2012
2012 Urine biomarkers predict acute kidney injury in newborns.Journal of Pediatrics.  161:270-5.e1. 2012
2012 Outcome trajectories in extremely preterm infants.Pediatrics.  130:e115-e125. 2012
2012 Approach to infants born at 22 to 24 weeks' gestation: relationship to outcomes of more-mature infants.Pediatrics.  129:e1508-e1516. 2012
2012 Temporary fetal tracheal occlusion using a gel plug in a rabbit model of congenital diaphragmatic hernia.Journal of Pediatric Surgery.  47:1063-1066. 2012
2012 Thy-1 signals through PPARγ to promote lipofibroblast differentiation in the developing lung.American Journal of Respiratory Cell and Molecular Biology.  46:765-772. 2012
2012 Gentle ventilation: the new evidence from the SUPPORT, COIN, VON, CURPAP, Colombian Network, and Neocosur Network trials.Early Human Development.  88 Suppl 2:S81-S83. 2012
2012 In vitro studies on the effect of particle size on macrophage responses to nanodiamond wear debris.Acta Biomaterialia.  8:1939-1947. 2012
2012 Neurodevelopmental outcomes in infants requiring resuscitation in developing countries.Journal of Pediatrics.  160:781-5.e1. 2012
2012 Transforming growth factor-β regulates endothelin-1 signaling in the newborn mouse lung during hypoxia exposure.AJP - Lung Cellular and Molecular Physiology.  302:L857-L865. 2012
2012 Prospective analysis of pulmonary hypertension in extremely low birth weight infants.Pediatrics.  129:e682-e689. 2012
2012 ABO blood group is associated with response to inhaled nitric oxide in neonates with respiratory failure.PLoS ONE.  7:e45164. 2012
2011 Association of antenatal corticosteroids with mortality and neurodevelopmental outcomes among infants born at 22 to 25 weeks' gestation.Journal of the American Medical Association.  306:2348-2358. 2011
2011 Cytokines and neurodevelopmental outcomes in extremely low birth weight infants.Journal of Pediatrics.  159:919-25.e3. 2011
2011 Hypoxia induces downregulation of PPAR-γ in isolated pulmonary arterial smooth muscle cells and in rat lung via transforming growth factor-β signaling.AJP - Lung Cellular and Molecular Physiology.  301:L899-L907. 2011
2011 Urine biomarkers predict acute kidney injury and mortality in very low birth weight infants.Journal of Pediatrics.  159:907-12.e1. 2011
2011 Identification of extremely premature infants at high risk of rehospitalization.Pediatrics.  128:e1216-e1225. 2011
2011 Baseline values of candidate urine acute kidney injury biomarkers vary by gestational age in premature infants.Pediatric Research.  70:302-306. 2011
2011 Accuracy of a novel system for oxygen delivery to small children.Pediatrics.  128:e382-e387. 2011
2011 Hypoxia-induced inhibition of lung development is attenuated by the peroxisome proliferator-activated receptor-γ agonist rosiglitazone.AJP - Lung Cellular and Molecular Physiology.  301:L125-L134. 2011
2011 Prediction of bronchopulmonary dysplasia by postnatal age in extremely premature infants.American Journal of Respiratory and Critical Care Medicine.  183:1715-1722. 2011
2011 Peptide-directed highly selective targeting of pulmonary arterial hypertension.American Journal of Pathology.  178:2489-2495. 2011
2011 Acute kidney injury reduces survival in very low birth weight infants.Pediatric Research.  69:354-358. 2011
2011 Acute kidney injury and renal replacement therapy independently predict mortality in neonatal and pediatric noncardiac patients on extracorporeal membrane oxygenation.Pediatric Critical Care Medicine.  12:e1-e6. 2011
2011 Intercenter differences in bronchopulmonary dysplasia or death among very low birth weight infants.Pediatrics.  127:e106-e116. 2011
2011 TGF-β2 suppresses macrophage cytokine production and mucosal inflammatory responses in the developing intestine.Gastroenterology.  140:242-253. 2011
2010 High mortality rates for very low birth weight infants in developing countries despite training.Pediatrics.  126:e1072-e1080. 2010
2010 Newborn care training of midwives and neonatal and perinatal mortality rates in a developing country.Pediatrics.  126:e1064-e1071. 2010
2010 Optimum oxygen therapy to prevent retinopathy of prematurity.Expert Review of Ophthalmology.  5:583-585. 2010
2010 Impact of timing of birth and resident duty-hour restrictions on outcomes for small preterm infants.Pediatrics.  126:222-231. 2010
2010 Prophylactic phenobarbital and whole-body cooling for neonatal hypoxic-ischemic encephalopathy.Journal of Pediatrics.  157:334-336. 2010
2010 Vitamin A and retinoic acid act synergistically to increase lung retinyl esters during normoxia and reduce hyperoxic lung injury in newborn mice.Pediatric Research.  67:591-597. 2010
2010 Early CPAP versus surfactant in extremely preterm infants.New England Journal of Medicine.  362:1970-1979. 2010
2010 Target ranges of oxygen saturation in extremely preterm infants.New England Journal of Medicine.  362:1959-1969. 2010
2010 Outcome of term infants using apgar scores at 10 minutes following hypoxic-ischemic encephalopathyObstetrical and Gynecological Survey.  65:217-218. 2010
2010 Newborn-care training and perinatal mortality in developing countries.New England Journal of Medicine.  362:614-623. 2010
2010 Predicting time to hospital discharge for extremely preterm infants.Pediatrics.  125:e146-e154. 2010
2009 A pumpless lung assist device reduces mechanical ventilation-induced lung injury in juvenile piglets.Pediatric Research.  66:671-676. 2009
2009 Evaluation of a pumpless lung assist device in hypoxia-induced pulmonary hypertension in juvenile piglets.Pediatric Research.  66:677-681. 2009
2009 Outcome of term infants using apgar scores at 10 minutes following hypoxic-ischemic encephalopathy.Pediatrics.  124:1619-1626. 2009
2009 PaCO2 and neurodevelopment in extremely low birth weight infants.Journal of Pediatrics.  155:217-21.e1. 2009
2009 Translating medical knowledge into practice: improving health care.Acta Paediatrica.  98:1242-1243. 2009
2009 Hyperoxia-induced neonatal rat lung injury involves activation of TGF-{beta} and Wnt signaling and is protected by rosiglitazone.AJP - Lung Cellular and Molecular Physiology.  296:L1031-L1041. 2009
2009 Acute kidney injury is independently associated with mortality in very low birthweight infants: a matched case-control analysis.Pediatric Nephrology.  24:991-997. 2009
2009 Loss of Thy-1 inhibits alveolar development in the newborn mouse lung.AJP - Lung Cellular and Molecular Physiology.  296:L738-L750. 2009
2009 Cytokines associated with bronchopulmonary dysplasia or death in extremely low birth weight infants.Pediatrics.  123:1132-1141. 2009
2009 Educational impact of the neonatal resuscitation program in low-risk delivery centers in a developing country.Journal of Pediatrics.  154:504-508.e5. 2009
2009 Acute kidney injury in critically ill newborns: what do we know? What do we need to learn?Pediatric Nephrology.  24:265-274. 2009
2009 Permissive hypercapnia to decrease lung injury in ventilated preterm neonates.Seminars in Neonatology..  14:21-27. 2009
2009 Nitric oxide administration using an oxygen hood: a pilot trial.PLoS ONE.  4:e4312. 2009
2009 Prolonged duration of initial empirical antibiotic treatment is associated with increased rates of necrotizing enterocolitis and death for extremely low birth weight infants.Pediatrics.  123:58-66. 2009
2008 Mortality and morbidity by month of birth of neonates admitted to an academic neonatal intensive care unit.Pediatrics.  122:e1048-e1052. 2008
2008 Should nasal high-frequency ventilation be used in preterm infants?Acta Paediatrica.  97:1484-1485. 2008
2008 Developmental regulation of NO-mediated VEGF-induced effects in the lung.American Journal of Respiratory Cell and Molecular Biology.  39:420-430. 2008
2008 Neonatal mortality among low birth weight infants during the initial months of the academic year.Journal of Perinatology.  28:691-695. 2008
2008 How can we prevent early death in preterm infants?Jornal de Pediatria.  84:283-285. 2008
2008 SNO-hemoglobin is not essential for red blood cell-dependent hypoxic vasodilation.Nature Medicine.  14:773-777. 2008
2008 Transforming growth factor-beta signaling mediates hypoxia-induced pulmonary arterial remodeling and inhibition of alveolar development in newborn mouse lung.AJP - Lung Cellular and Molecular Physiology.  295:L86-L95. 2008
2008 Predictors of death or bronchopulmonary dysplasia in preterm infants with respiratory failure.Journal of Perinatology.  28:420-426. 2008
2008 Role of matrix metalloproteinase-2 in newborn mouse lungs under hypoxic conditions.Pediatric Research.  63:26-32. 2008
2007 Clinical data predict neurodevelopmental outcome better than head ultrasound in extremely low birth weight infants.Journal of Pediatrics.  151:500-505.e2. 2007
2007 ReplyJournal of Pediatrics.  150. 2007
2007 Endothelin-1 mediates hypoxia-induced increases in vascular collagen in the newborn mouse lung.Pediatric Research.  61:559-564. 2007
2007 In reply [12]Pediatrics (Spanish Edition).  119:1039-1040. 2007
2007 Both extremes of arterial carbon dioxide pressure and the magnitude of fluctuations in arterial carbon dioxide pressure are associated with severe intraventricular hemorrhage in preterm infants.Pediatrics.  119:299-305. 2007
2007 Can lung ultrasound scanning be a useful diagnostic tool in neonates with respiratory distress?Biology of the Neonate.  91:210-211. 2007
2007 Retinoic acid combined with vitamin A synergizes to increase retinyl ester storage in the lungs of newborn and dexamethasone-treated neonatal rats.Biology of the Neonate.  92:26-32. 2007
2006 Predicting outcomes of neonates diagnosed with hypoxemic-ischemic encephalopathy.Pediatrics.  118:2084-2093. 2006
2006 Atrial natriuretic peptide-dependent modulation of hypoxia-induced pulmonary vascular remodeling.Life Sciences.  79:1357-1365. 2006
2006 Ventilatory strategies in the prevention and management of bronchopulmonary dysplasia.Seminars in Perinatology.  30:192-199. 2006
2006 Vitamin A combined with retinoic acid increases retinol uptake and lung retinyl ester formation in a synergistic manner in neonatal rats.Journal of Lipid Research.  47:1844-1851. 2006
2006 Endothelin-A receptor blockade inhibits the effects of hypoxia on the newborn lung vasculature.The Scientific World Journal.  6:669-670. 2006
2006 Reply to 'Zero-filled values enhanced the performance of CRP vs RBP: TTR index in ELBW infants' by Dr Rosales [2]Journal of Perinatology.  26:320. 2006
2006 Early prediction of poor outcome in extremely low birth weight infants by classification tree analysis.Journal of Pediatrics.  148:438-444. 2006
2006 Dominant negative mutation of the TGF-beta receptor blocks hypoxia-induced pulmonary vascular remodeling.Journal of applied physiology: respiratory, environmental and exercise physiology.  100:564-571. 2006
2005 Prediction of death for extremely low birth weight neonates.Pediatrics.  116:1367-1373. 2005
2005 Retinol-binding protein, transthyretin, and C-reactive protein in extremely low birth weight (ELBW) infants.Journal of Perinatology.  25:714-719. 2005
2005 Surfactant therapyIndian Journal of Pediatrics.  7:192-200. 2005
2005 Doxycycline inhibits matrix metalloproteinase-2 (MMP-2) production by neonatal pulmonary artery endothelial cellsEthnicity and Disease.  15. 2005
2005 Inadequacy of IV vitamin A supplementation of extremely preterm infants?Journal of Pediatrics.  146:846-847. 2005
2005 Endothelin-A receptor blockade prevents and partially reverses neonatal hypoxic pulmonary vascular remodeling.Pediatric Research.  57:631-636. 2005
2005 Vitamin A supplementation for extremely low birth weight infants: outcome at 18 to 22 months.Pediatrics.  115:e249-e254. 2005
2004 Bronchopulmonary dysplasia: new insights.Clinics in Perinatology.  31:613-628. 2004
2004 Survey of vitamin A supplementation for extremely-low-birth-weight infants: is clinical practice consistent with the evidence?Journal of Pediatrics.  145:304-307. 2004
2004 Bias in reported neurodevelopmental outcomes among extremely low birth weight survivorsPediatrics.  114:404-410. 2004
2004 Bias in reported neurodevelopmental outcomes among extremely low birth weight survivors.Pediatrics.  114:404-410. 2004
2004 Care of very low birth weight infants with respiratory distress syndrome: an evidence-based review.Minerva Pediatrica.  56:373-380. 2004
2004 Permissive hypercapnia during mechanical ventilation of neonates.Indian Pediatrics.  41:775-778. 2004
2004 Gastric residuals in prediction of necrotizing enterocolitis in very low birth weight infants.Pediatrics.  113:1848-1849. 2004
2004 Gastric Residuals and Their Relationship to Necrotizing Enterocolitis in Very Low Birth Weight InfantsPediatrics.  113:50-53. 2004
2004 Gastric residuals and their relationship to necrotizing enterocolitis in very low birth weight infants.Pediatrics.  113:50-53. 2004
2003 A comparison of three vitamin A dosing regimens in extremely-low-birth-weight infants.Journal of Pediatrics.  142:656-661. 2003
2003 The mismatch between evidence and practice. Common therapies in search of evidence.Clinics in Perinatology.  30:305-331. 2003
2003 Peptide growth factors in tracheal aspirates of mechanically ventilated preterm neonates.Pediatric Research.  53:240-244. 2003
2002 Endothelin-A receptor blockade in porcine pulmonary hypertension.Pediatric Research.  52:913-921. 2002
2002 Endothelin-A receptor blockade in porcine pulmonary hypertension.Pediatric Research.  52:913-921. 2002
2002 Feasibility of nitric oxide administration by oxygen hood in neonatal pulmonary hypertensionJournal of Perinatology.  22:50-56. 2002
2002 Feasibility of nitric oxide administration by oxygen hood in neonatal pulmonary hypertension.Journal of Perinatology.  22:50-56. 2002
2001 Comparison of the prediction of extremely low birth weight neonatal mortality by regression analysis and by neural networks.Early Human Development.  65:123-137. 2001
2001 Hypocapnia and hypercapnia in respiratory management of newborn infants.Clinics in Perinatology.  28:517-531. 2001
2001 Hemodynamic effects of levcromakalim in neonatal porcine pulmonary hypertension.Biology of the Neonate.  80:74-80. 2001
2001 Effect of cigarette smoke extract on neonatal porcine vascular smooth muscle cells.Toxicology and Applied Pharmacology.  170:130-136. 2001
2001 Chronic exposure to cigarette smoke extract impairs endothelium-dependent relaxation of chicken embryo pulmonary arteries.Biology of the Neonate.  80:247-250. 2001
2000 Prediction of neurologic morbidity in extremely low birth weight infantsJournal of Perinatology.  20:496-503. 2000
2000 Prediction of neurologic morbidity in extremely low birth weight infants.Journal of Perinatology.  20:496-503. 2000
1999 Conventional mechanical ventilation: traditional and new strategies.Pediatrics in Review.  20:e117-e126. 1999
1999 Hypoxia-induced release of peptide growth factors from neonatal porcine pulmonary artery smooth muscle cells.Biology of the Neonate.  76:311-319. 1999
1999 Role of nitric oxide in regulating neonatal porcine pulmonary artery smooth muscle cell proliferation.Biology of the Neonate.  76:291-300. 1999
1999 Analgesia for ventilated neonates: where do we stand?Journal of Pediatrics.  135:403-405. 1999
1999 Randomized trial of "slow" versus "fast" feed advancements on the incidence of necrotizing enterocolitis in very low birth weight infants.Journal of Pediatrics.  134:293-297. 1999
1997 Valvular heart disease: rheumatic or rheumatoid?Indian Pediatrics.  34:641-644. 1997
Effect of Therapeutic Hypothermia Initiated After 6 Hours of Age on Death or Disability Among Newborns With Hypoxic-Ischemic Encephalopathy: A Randomized Clinical Trial.Journal of the American Medical Association.  318:1550-1560.
Effects of Myo-inositol on Type 1 Retinopathy of Prematurity Among Preterm Infants <28 Weeks' Gestational Age: A Randomized Clinical Trial.Journal of the American Medical Association.  320:1649-1658.

Book

Year Title Altmetric
2016 Term and Preterm Infants..  Ed. 114.  2016

Chapter

Year Title Altmetric
2016 Blood Gases: Technical Aspects and Interpretation.  80-96.e3. 2016
2016 Medical and Surgical Interventions for Respiratory Distress and Airway Management.  391-406.e2. 2016
2011 Ventilation Strategies.  265-276. 2011
2006 Basic Principles of Mechanical Ventilation.  61-73. 2006
2006 Classification of Mechanical Ventilation Devices.  74-80. 2006
2006 Ventilator Parameters.  81-85. 2006
2003 Ventilatory Strategies.  249-259. 2003

Principal Investigator On

  • Pre-Vent Apnea  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2016 - 2021
  • Attenuation of the Congenital Central Hypoventilation Syndrome (CCHS) Phenotype In Vitro and In Vivo by HSP90 Inhibition  awarded by CONGENITAL CENTRAL HYPOVENTILATION SYNDROME FAMILY NETWORK 2017 - 2019
  • STOP BPD  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2015 - 2019
  • Alveolar DevMAP  awarded by Duke University 2015 - 2019
  • Alveolar DevMAP  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2014 - 2019
  • Private Grant  awarded by EXELIXIS, INC. 2018 - 2019
  • Private Grant  awarded by BAEBIES, INC. 2018
  • Azithromycin to Prevent BPD in Ureaplasma-infected Preterms  awarded by University of Maryland 2017 - 2018
  • Cerebral Oxygenation and Autoregulation in Preterm Infants: Association with Morbidity and Mortality  awarded by Stanford University 2014 - 2018
  • Pharmacokinetics of Slidenafil in Premature Infants  awarded by Duke University 2013 - 2017
  • Azithromycin to Prevent BPD in Ureaplasma-Infected Preterms  awarded by UNIVERSITY OF MARYLAND (BALTIMORE) 2011 - 2017
  • Private Grant  awarded by Pfizer Inc., U.S. Pharmaceuticals Group 2013 - 2016
  • Vitamin Supplementation and Retinal Metabolism in the Neonatal Period  awarded by Pennsylvania State University 2010 - 2015
  • Early Vitamin D Supplementation for Prevention of Respiratory Morbidity in Extremely Preterm Infants: A Randomized Clinical Trial  awarded by KAUL PEDIATRIC RESEARCH INSTITUTE 2012 - 2015
  • DNA Methylation Changes in Lung Samples of Infants with Bronchopulmonary Dysplasia  awarded by American Academy of Pediatrics 2013 - 2014
  • Transforming Growth Factor - Beta Mediates Effects of Hypoxia in Newborn Lung  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2008 - 2014
  • Private Grant  awarded by MEAD JOHNSON NUTRITION - NEW 2013
  • Retinoids and Hyperoxic Lung Injury  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2010 - 2013
  • Novel Genetic and Salivary Glycan Biomarkers for Risk of NEC in ELBW Infants.  awarded by CHILDREN'S HOSPITAL MEDICAL CENTER (CINCINNATI) 2009 - 2012
  • Private Grant  awarded by SPECTROS CORPORATION 2011 - 2012
  • Private Grant  awarded by IKARIA 2011
  • UNC Clinical and Translational Science Award  awarded by University of North Carolina at Chapel Hill 2009 - 2011
  • Investigator On

  • CIALIS® Reverses Halogen Induced Injury to Pregnant Animals and Their Offspring  awarded by National Institute of Environmental Health Sciences/NIH/DHHS 2016 - 2021
  • Private Grant  awarded by WINDTREE THERAPEUTICS, INC. 2016 - 2021
  • Cooperative Multi-center Neonatal Research Network-UAB  awarded by National Institute of Child Health and Human Development/NIH/DHHS 2016 - 2021
  • NICHD Maternal-Fetal Medicine Units (MFMU) Network  awarded by National Institute of Child Health and Human Development/NIH/DHHS 2016 - 2021
  • Chronic Hypertension and Pregnancy-CHAP Clinical Coordinating Center  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2014 - 2020
  • UAB Predoctoral Training Grant in Translational and Molecular Sciences  awarded by National Institute of General Medical Sciences/NIH/DHHS 2015 - 2020
  • Targeting Thioredoxin Reductase-1 to Prevent Bronchopulmonary Dysplasia  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2015 - 2019
  • Matrix Metalloproteinase Driven Lung Inflammation in RSV Disease  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2014 - 2019
  • NICHD Neonatal Research Network (NRN)  awarded by RTI INTERNATIONAL 2017 - 2019
  • Mechanisms by Which Retinoids Attenuate Hyperoxia-Induced Memory Deficit in Mice  awarded by KAUL PEDIATRIC RESEARCH INSTITUTE 2016 - 2018
  • A Phase II Multi-site Study of Autologous Cord Blood Cells for Hypoxic lschemic Encephalopathy (HIE)  awarded by Duke University 2016 - 2018
  • Cooperative Multi-Center Neonatal Research Network  awarded by RESEARCH TRIANGLE INSTITUTE 2010 - 2017
  • Mechanisms of Pulmonary Fibrosis in CF Lung Disease  awarded by KAUL PEDIATRIC RESEARCH INSTITUTE 2015 - 2016
  • Private Grant  awarded by DISCOVERY LABORATORIES, INC. 2014 - 2016
  • Prematurity Prevention and Research Related to the Microbiome (PREPARE-M)  awarded by UNIVERSITY OF ALABAMA HEALTH SERVICES FOUNDATION 2015 - 2016
  • Mechanisms and Countermeasures of Halogen-Induced Injury to Pregnant Mice  awarded by National Institute of Environmental Health Sciences/NIH/DHHS 2015 - 2016
  • Cooperative Multicenter Neonatal Research Network - UAB  awarded by National Institute of Child Health and Human Development/NIH/DHHS 2011 - 2016
  • Private Grant  awarded by DISCOVERY LABORATORIES, INC. 2014 - 2016
  • Effect of Vitamin D Deficiency on Murine Lung Development and Function  awarded by KAUL PEDIATRIC RESEARCH INSTITUTE 2013 - 2015
  • Prematurity Prevention and Research Related to the Microbiome (PREPARE-M)  awarded by UNIVERSITY OF ALABAMA HEALTH SERVICES FOUNDATION 2013 - 2015
  • Cesarean Section Optimal Antibiotic Prophylaxis (C/SOAP) Trial  awarded by National Institute of Child Health and Human Development/NIH/DHHS 2010 - 2015
  • UAB Research Development Program Component II - Overall Program  awarded by Cystic Fibrosis Foundation 2015
  • Private Grant  awarded by CADENCE PHARMACEUTICALS, INC. 2013 - 2015
  • Pediatric Critical Care Scientist Development Program: "RSV-Induced Respiratory Failure: Role of MMP-9 in Lung Injury Through Generation of PGP"  awarded by University of Utah 2012 - 2013
  • Education And Training

  • Doctor of Medicine, Foreign University
  • Jawaharlal Institute Post Graduate Medicine, Internship 1990
  • Postgraduate Institute of Medical Education & Res., Residency 1993
  • Full Name

  • Namasivayam Ambalavanan
  • Blazerid

  • ambal