Positions

Overview

  • Dr. Kundu received his master's degree from the Indian Institute of Technology Kharagpur (IIT-KGP) in India followed by his research training at the National University of Singapore's (NUS) Biomedical Engineering Department. He subsequently earned his Ph.D. in Molecular Biology and Biochemistry from IIT-KGP. In his postdoctoral training at the University of Alabama at Birmingham (UAB), Dr. Kundu studied epigenetic, epitranscriptomic, and metabolic regulations in kidney cancer. After his training, Dr. Kundu joined as a staff researcher in the Department of Urology at UAB and currently, he is serving the position of an instructor in the department.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2021 The TGF-β/HDAC7 axis suppresses TCA cycle metabolism in renal cancerJCI Insight.  6. 2021
    2021 TGF-β signaling suppresses TCA cycle metabolism in renal cancer 2021
    2020 Teleological role of L-2-hydroxyglutarate dehydrogenase in the kidneyDisease Models and Mechanisms.  13. 2020
    2020 Biochemical Characterization of VapC46 Toxin from Mycobacterium tuberculosisMolecular Biotechnology.  62:335-343. 2020
    2020 PGC1α suppresses kidney cancer progression by inhibiting collagen-induced SNAIL expressionMatrix Biology.  89:43-58. 2020
    2020 PRDM16 suppresses HIF-targeted gene expression in kidney cancerJournal of Experimental Medicine.  217. 2020
    2020 Dynamic Regulation of TET2 by Phosphorylation and Dephosphorylation at Ser99 2020
    2020 14-3-3 proteins protect AMPK-phosphorylated ten-eleven translocation-2 (TET2) from PP2A-mediated dephosphorylationJournal of Biological Chemistry.  295:1754-1766. 2020
    2020 Teleological Role of L-2-Hydroxyglutarate Dehydrogenase in the Kidney.Disease Models and Mechanisms2020
    2019 Structural characterization of VapB46 antitoxin from Mycobacterium tuberculosis: insights into VapB46–DNA binding 2019
    2019 Integrative epigenetic and gene expression analysis of renal tumor progression to metastasisMolecular Cancer Research.  17:84-96. 2019
    2018 Biochemical and epigenetic insights into L-2-hydroxyglutarate, a potential therapeutic target in renal cancerClinical Cancer Research.  24:6433-6446. 2018
    2018 Abstract 4483: Functional implications of PRDM16 loss in kidney cancerCancer Research.  78:4483-4483. 2018
    2018 Abstract 5482: L-2HG/ L2HGDH axis as therapeutic target for kidney cancerCancer Research.  78:5482-5482. 2018
    2017 Molecular insights into RNA-binding properties of Escherichia coli–expressed RNA-dependent RNA polymerase of Antheraea mylitta cytoplasmic polyhedrosis virusArchives of Virology.  162:2727-2736. 2017
    2016 Macroscopic amyloid fiber formation by staphylococcal biofilm associated SuhB proteinBiophysical Chemistry.  217:32-41. 2016
    2016 Reconstitution of the RNA-dependent RNA polymerase activity of Antheraea mylitta cypovirus in vitro using separately expressed different functional domains of the enzymeJournal of General Virology.  97:1709-1719. 2016
    2015 Functional insights from molecular modeling, docking, and dynamics study of a cypoviral RNA dependent RNA polymeraseJournal of Molecular Graphics and Modelling.  61:160-174. 2015
    2015 Complete catalytic cycle of cofactor-independent phosphoglycerate mutase involves a spring-loaded mechanism 2015
    2015 Genome segment 4 of Antheraea mylitta cytoplasmic polyhedrosis virus encodes RNA triphosphatase and methyltransferasesJournal of General Virology.  96:95-105. 2015
    2014 Genome segment 5 of Antheraea mylitta cytoplasmic polyhedrosis virus encodes a bona fide guanylyltransferaseVirology Journal.  11. 2014
    2014 Expression, purification, crystallization and preliminary X-ray diffraction studies of phosphoglycerate mutase from Staphylococcus aureus NCTC8325Acta Crystallographica Section F: Structural Biology Communications.  70:53-56. 2014

    Research Overview

  • 1) Kidney cancer
    2)Epigenetics and epitranscriptomics
    3)Post-transcription regulation
    4)Cell signaling
    5)Metabolism
    6)DNA damage repair
  • Education And Training

  • Doctor of Science in Molecular Biology, 2016
  • Full Name

  • Anirban Kundu