Positions

Selected Publications

Academic Article

Year Title Altmetric
2017 Activated T lymphocytes are essential drivers of pathological remodeling in ischemic heart failureCirculation: Heart Failure.  10. 2017
2017 Leukocyte iNOS is required for inflammation and pathological remodeling in ischemic heart failureBasic Research in Cardiology.  112. 2017
2017 Cardiac inflammation in genetic dilated cardiomyopathy caused by MYBPC3 mutationJournal of Molecular and Cellular Cardiology.  102:83-93. 2017
2017 Mononuclear phagocytes are dispensable for cardiac remodeling in established pressure-overload heart failurePLoS ONE.  12. 2017
2016 Abstract 18912: Platelet Derived Growth Factor Promotes Myofibroblastic Differentiation of Cardiac Resident Mesenchymal Stem Cells and Exacerbates Post-Infarction Left Ventricular RemodelingCirculation.  134:A18912. 2016
2016 Abstract 20260: CD4<sup>+</sup> T- Lymphocyte Recruitment Into the Failing Heart is Indispensable for the Progression of Adverse Left Ventricular RemodelingCirculation.  134:A20260. 2016
2016 Abstract 14883: Remodeling of the Mononuclear Phagocyte Network Underlies Chronic Inflammation and Disease Progression in Heart Failure: Importance of the Cardiosplenic AxisCirculation.  128:A14883. 2016
2016 Abstract 19635: Glutathione-S-Transferase P Regulates Endothelial Progenitor Cell (EPC) Function in a c-Jun N-terminal kinase(JNK)-Dependent Manner and Enhances Neovascularization in Post-Infarction Heart FailureCirculation.  126:A19635. 2016
2016 Abstract 19698: Altered Dendritic Cell Network in Chronic Heart Failure - Implications for Chronic InflammationCirculation.  126:A19698. 2016
2016 TNF receptor signaling inhibits cardiomyogenic differentiation of cardiac stem cells and promotes a neuroadrenergic-like fateAJP - Heart and Circulatory Physiology.  311:H1189-H1201. 2016
2015 Abstract 17097: M2 Macrophage Polarization Promotes Neovascularization in vivoCirculation.  124:A17097. 2015
2015 Abstract 17284: Selective Macrophage Ablation Attenuates Diet-Induced Obesity and Insulin Resistance and Reverses Diabetic CardiomyopathyCirculation.  124:A17284. 2015
2015 Abstract 18198: The Spleen Regulates Apoptotic Cell Clearance, Tissue Neovascularization, and Wound Healing After Myocardial InfarctionCirculation.  132:A18198. 2015
2015 Abstract 18244: Macrophages Infiltrate the Heart With Activation of Adaptive Immunity During Compensated Pressure Overload HypertrophyCirculation.  132:A18244. 2015
2015 Abstract 18821: Dysfunctional Regulatory T-Lymphocytes Promote Inflammation and Adverse Cardiac Remodeling in Chronic Ischemic Heart FailureCirculation.  132:A18821. 2015
2015 Abstract 221: Chronic Alterations of the Tissue Dendritic Cell and Macrophage Network Underlies the Th1 Response in the Failing HeartCirculation Research.  111:A221. 2015
2015 Abstract 90: The Spleen Is an Essential Regulator of Systemic Neovascularization In VivoCirculation Research.  111:A90. 2015
2014 Abstract 60: The Role of Mononuclear Phagocytes in Pressure Overload Heart FailureCirculation Research.  115:A60. 2014
2014 Remodeling of the mononuclear phagocyte network underlies chronic inflammation and disease progression in heart failure critical importance of the cardiosplenic axisCirculation Research.  114:266-282. 2014
2013 Cardiac immune cell remodeling after myocardial infarctionJournal of Molecular and Cellular Cardiology.  62:142-143. 2013
2012 Direct measurement of blood flow in microvessels grown in Matrigel in vivoJournal of Surgical Research.  172. 2012
2011 Chronic oral exposure to the aldehyde pollutant acrolein induces dilated cardiomyopathyAJP - Heart and Circulatory Physiology.  301. 2011
2011 Tumor necrosis factor receptor 2 signaling limits β-adrenergic receptor-mediated cardiac hypertrophy in vivoBasic Research in Cardiology.  106:1193-1205. 2011
2011 Role of vacuolar ATPase in the trafficking of renal type IIa sodium-phosphate cotransporterCellular Physiology and Biochemistry.  27:703-714. 2011
2010 Microfluidic Cardiac Cell Culture Model (μCCCM)Analytical Chemistry.  82:7581-7587. 2010
2008 PTH-mediated regulation of Na + -K + -ATPase requires Src kinase-dependent ERK phosphorylationAJP - Renal Physiology.  295:F426-F437. 2008
2007 Ouabain stimulates protein kinase B (Akt) phosphorylation in opossum kidney proximal tubule cells through an ERK-dependent pathwayAmerican Journal of Physiology - Cell Physiology.  293:C1171-C1180. 2007
2006 Ouabain induces cell proliferation through calcium-dependent phosphorylation of Akt (protein kinase B) in opossum kidney proximal tubule cellsAmerican Journal of Physiology - Cell Physiology.  291:C1247-C1257. 2006

Education And Training

  • Doctor of Philosophy in Biochemistry, Biophysics and Molecular Biology, Hamdard University 2004
  • Full Name

  • Mohamed Ameen Mohamed Ismahil