Positions

Selected Publications

Academic Article

Year Title Altmetric
2017 Activated T Lymphocytes are Essential Drivers of Pathological Remodeling in Ischemic Heart Failure.Circulation: Heart Failure.  10:e003688. 2017
2017 Leukocyte iNOS is required for inflammation and pathological remodeling in ischemic heart failure.Basic Research in Cardiology.  112:19. 2017
2017 Cardiac inflammation in genetic dilated cardiomyopathy caused by MYBPC3 mutation.Journal of Molecular and Cellular Cardiology.  102:83-93. 2017
2017 Mononuclear Phagocytes Are Dispensable for Cardiac Remodeling in Established Pressure-Overload Heart Failure.PLoS ONE.  12:e0170781. 2017
2016 Abstract 18912: Platelet Derived Growth Factor Promotes Myofibroblastic Differentiation of Cardiac Resident Mesenchymal Stem Cells and Exacerbates Post-Infarction Left Ventricular RemodelingCirculation.  134:A18912. 2016
2016 Abstract 20260: CD4<sup>+</sup> T- Lymphocyte Recruitment Into the Failing Heart is Indispensable for the Progression of Adverse Left Ventricular RemodelingCirculation.  134:A20260. 2016
2016 TNF receptor signaling inhibits cardiomyogenic differentiation of cardiac stem cells and promotes a neuroadrenergic-like fate.AJP - Heart and Circulatory Physiology.  311:H1189-H1201. 2016
2016 Abstract 14883: Remodeling of the Mononuclear Phagocyte Network Underlies Chronic Inflammation and Disease Progression in Heart Failure: Importance of the Cardiosplenic AxisCirculation.  128:A14883. 2016
2016 Abstract 19635: Glutathione-S-Transferase P Regulates Endothelial Progenitor Cell (EPC) Function in a c-Jun N-terminal kinase(JNK)-Dependent Manner and Enhances Neovascularization in Post-Infarction Heart FailureCirculation.  126:A19635. 2016
2016 Abstract 19698: Altered Dendritic Cell Network in Chronic Heart Failure - Implications for Chronic InflammationCirculation.  126:A19698. 2016
2015 Abstract 17097: M2 Macrophage Polarization Promotes Neovascularization in vivoCirculation.  124:A17097. 2015
2015 Abstract 17284: Selective Macrophage Ablation Attenuates Diet-Induced Obesity and Insulin Resistance and Reverses Diabetic CardiomyopathyCirculation.  124:A17284. 2015
2015 Abstract 18198: The Spleen Regulates Apoptotic Cell Clearance, Tissue Neovascularization, and Wound Healing After Myocardial InfarctionCirculation.  132:A18198. 2015
2015 Abstract 18244: Macrophages Infiltrate the Heart With Activation of Adaptive Immunity During Compensated Pressure Overload HypertrophyCirculation.  132:A18244. 2015
2015 Abstract 18821: Dysfunctional Regulatory T-Lymphocytes Promote Inflammation and Adverse Cardiac Remodeling in Chronic Ischemic Heart FailureCirculation.  132:A18821. 2015
2015 Abstract 221: Chronic Alterations of the Tissue Dendritic Cell and Macrophage Network Underlies the Th1 Response in the Failing HeartCirculation Research.  111:A221. 2015
2015 Abstract 90: The Spleen Is an Essential Regulator of Systemic Neovascularization In VivoCirculation Research.  111:A90. 2015
2014 Abstract 60: The Role of Mononuclear Phagocytes in Pressure Overload Heart FailureCirculation Research.  115:A60. 2014
2014 Remodeling of the mononuclear phagocyte network underlies chronic inflammation and disease progression in heart failure: critical importance of the cardiosplenic axis.Circulation Research.  114:266-282. 2014
2013 Cardiac immune cell remodeling after myocardial infarction.Journal of Molecular and Cellular Cardiology.  62:142-143. 2013
2012 Direct measurement of blood flow in microvessels grown in Matrigel in vivo.Journal of Surgical Research.  172:e55-e60. 2012
2011 Chronic oral exposure to the aldehyde pollutant acrolein induces dilated cardiomyopathy.AJP - Heart and Circulatory Physiology.  301:H2050-H2060. 2011
2011 Tumor necrosis factor receptor 2 signaling limits β-adrenergic receptor-mediated cardiac hypertrophy in vivo.Basic Research in Cardiology.  106:1193-1205. 2011
2011 Role of vacuolar ATPase in the trafficking of renal type IIa sodium-phosphate cotransporter.Cellular Physiology and Biochemistry.  27:703-714. 2011
2010 Microfluidic cardiac cell culture model (μCCCM).Analytical Chemistry.  82:7581-7587. 2010
2008 PTH-mediated regulation of Na + -K + -ATPase requires Src kinase-dependent ERK phosphorylationAJP - Renal Physiology.  295:F426-F437. 2008
2007 Ouabain stimulates protein kinase B (Akt) phosphorylation in opossum kidney proximal tubule cells through an ERK-dependent pathwayAmerican Journal of Physiology - Cell Physiology.  293:C1171-C1180. 2007
2006 Ouabain induces cell proliferation through calcium-dependent phosphorylation of Akt (protein kinase B) in opossum kidney proximal tubule cellsAmerican Journal of Physiology - Cell Physiology.  291:C1247-C1257. 2006

Education And Training

  • Doctor of Philosophy in Biochemistry, Biophysics and Molecular Biology, Hamdard University
  • Full Name

  • Mohamed Mohamed Ismahil