Positions

Selected Publications

Academic Article

Year Title Altmetric
2020 Innate and Autoimmunity in the Pathogenesis of Inherited Retinal Dystrophy. 2020
2019 NudC regulates photoreceptor disk morphogenesis and rhodopsin localization 2019
2019 Mks6 mutations reveal tissue-and cell type-specific roles for the cilia transition zone 2019
2018 Autosomal dominant retinitis pigmentosa rhodopsin mutant Q344X drives specific alterations in chromatin complex gene transcription 2018
2016 Aberrant protein trafficking in retinal degenerations: The initial phase of retinal remodeling 2016
2016 Novel hypomorphic alleles of the mouse tyrosinase gene induced by CRISPR-Cas9 nucleases cause non-albino pigmentation phenotypes 2016
2014 Nucleotide bound to rab11a controls localization in rod cells but not interaction with rhodopsin 2014
2014 Abrupt onset of mutations in a developmentally regulated gene during terminal differentiation of post-mitotic photoreceptor neurons in mice 2014
2014 An activated unfolded protein response promotes retinal degeneration and triggers an inflammatory response in the mouse retina 2014
2013 Biochemical analysis of a rhodopsin photoactivatable GFP fusion as a model of G-protein coupled receptor transport 2013
2013 The age-regulating protein klotho is vital to sustain retinal function 2013
2013 The severe autosomal dominant retinitis pigmentosa rhodopsin mutant Ter349Glu mislocalizes and induces rapid rod cell death 2013
2012 Defective trafficking of rhodopsin and its role in retinal degenerations 2012
2012 In vitro biochemical assays to monitor rhodopsin function 2012
2012 In vitro biochemical assays to monitor rhodopsin function 2012
2010 1 rhodopsin mutations in congenital night blindness 2010
2010 Mutations of the opsin gene (Y102H and I307N) lead to light-induced degeneration of photoreceptors and constitutive activation of phototransduction in mice 2010
2008 Identification and functional characterization of a novel rhodopsin mutation associated with autosomal dominant CSNB 2008
2006 Defective development of photoreceptor membranes in a mouse model of recessive retinal degeneration 2006
2005 Rhodopsin-EGFP knock-ins for imaging quantal gene alterations 2005
2004 Evolution guided mutagenesis of rhodopsin 2004
2004 Functional Studies of a human rhodopsin-EGFP fusion in knock-in mice. 2004
2004 Evolutionary Trace of G Protein-coupled Receptors Reveals Clusters of Residues That Determine Global and Class-specific Functions 2004
2003 An opsin mutant with increased thermal stability 2003
2003 Characterization of rhodopsin congenital night blindness mutant T94I 2003
2003 Slow binding of retinal to rhodopsin mutants G90D and T94D 2003

Teaching Activities

  • GBS792 - CMDB Seminar (Spring Term 2020) 2020
  • VIS700 - Vision Science Lit Review (Spring Term 2020) 2020
  • GBS792 - CMDB Seminar (Fall Term 2019) 2019
  • VIS700 - Vision Science Lit Review (Fall Term 2019) 2019
  • VS113 - Biochemistry of the Eye (Fall Term 2019) 2019
  • GBS792 - CMDB Seminar (Spring Term 2019) 2019
  • GBSC742 - Student Theme Meeting Course (Spring Term 2019) 2019
  • VIS700 - Vision-Related Lit Review (Spring Term 2019) 2019
  • GBS792 - CMDB Seminar (Fall Term 2018) 2018
  • GBSC742 - Student Theme Meeting Course (Fall Term 2018) 2018
  • VIS700 - Vision-Related Lit Review (Fall Term 2018) 2018
  • VS113 - Biochemistry of the Eye (Fall Term 2018) 2018
  • GBS792 - CMDB Seminar (Spring Term 2018) 2018
  • VIS700 - Vision-Related Lit Review (Spring Term 2018) 2018
  • GBS792 - CMDB Seminar (Fall Term 2017) 2017
  • VIS700 - Vision-Related Lit Review (Fall Term 2017) 2017
  • VS113 - Biochemistry of the Eye (Fall Term 2017) 2017
  • GBS792 - CMDB Seminar (Spring Term 2017) 2017
  • VIS700 - Vision-Related Lit Review (Spring Term 2017) 2017
  • GBS792 - CMDB Seminar (Fall Term 2016) 2016
  • VIS700 - Vision-Related Lit Review (Fall Term 2016) 2016
  • VS113 - Biochemistry of the Eye (Fall Term 2016) 2016
  • VIS700 - Vision-Related Lit Review (Spring Term 2016) 2016
  • VS113 - Biochemistry of the Eye (Fall Term 2015) 2015
  • VIS700 - Vision-Related Lit Review (Fall Term 2015) 2015
  • VIS700 - Vision-Related Lit Review (Spring Term 2015) 2015
  • VS113 - Biochemistry of the Eye (Fall Term 2014) 2014
  • VIS700 - Vision-Related Lit Review (Fall Term 2014) 2014
  • VIS700 - Vision-Related Lit Review (Spring Term 2014) 2014
  • VS113 - Biochemistry of the Eye (Fall Term 2013) 2013
  • VIS700 - Vision-Related Lit Review (Fall Term 2013) 2013
  • VIS700 - Vision-Related Lit Review (Spring Term 2013) 2013
  • VS113 - Biochemistry of the Eye (Fall Term 2012) 2012
  • VIS700 - Vision-Related Lit Review (Fall Term 2012) 2012
  • VIS700 - Vision-Related Lit Review (Spring Term 2012) 2012
  • VS121 - Biochemistry of the Eye (Fall Term 2011) 2011
  • VIS700 - Vision-Related Lit Review (Fall Term 2011) 2011
  • VIS700 - Vision-Related Lit Review (Summer Term 2011) 2011
  • VIS700 - Vision-Related Lit Review (Spring Term 2011) 2011
  • VS121 - Biochemistry of the Eye (Fall Term 2010) 2010
  • STH299 - Interdisciplinary Seminar (Fall Term 2010) 2010
  • VIS700 - Vision-Related Lit Review (Fall Term 2010) 2010
  • VIS700 - Vision-Related Lit Review (Summer Term 2010) 2010
  • VIS700 - Vision-Related Lit Review (Spring Term 2010) 2010
  • STH299 - Interdisciplinary Seminar (Fall Term 2009) 2009
  • VIS700 - Vision-Related Lit Review (Fall Term 2009) 2009
  • OPVS111 - Basic Science/Clinical Opt I (Fall Term 2009) 2009
  • VIS700 - Vision-Related Lit Review (Summer Term 2009) 2009
  • Education And Training

  • Doctor of Philosophy in Biochemistry, Brandeis University 2002
  • Full Name

  • Alecia Gutierrez