Selected Publications

Academic Article

Year Title Altmetric
2018 Acetylation of ACAP4 regulates CCL18-elicited breast cancer cell migration and invasion.Journal of Molecular Cell Biology.  10:559-572. 2018
2017 Methods to Evaluate Cell Growth, Viability, and Response to Treatment in a Tissue Engineered Breast Cancer ModelScientific Reports.  7. 2017
2017 Silencing of TGF-β1 in tumor cells impacts MMP-9 in tumor microenvironmentScientific Reports.  7. 2017
2017 Computational and Experimental Analysis of Fluid Transport Through Three-Dimensional Collagen–Matrigel HydrogelsAnnals of Biomedical Engineering.  45:1027-1038. 2017
2017 Flow–perfusion bioreactor system for engineered breast cancer surrogates to be used in preclinical testingJournal of Tissue Engineering and Regenerative Medicine.  11:1242-1250. 2017
2016 Preparation and analysis of In Vitro three dimensional breast carcinoma surrogatesJournal of Visualized Experiments.  2016. 2016
2016 A recapitulative three-dimensional model of breast carcinoma requires perfusion for multi-week growthJournal of Tissue Engineering.  7. 2016
2015 Nucleic acid amplification from individual cells: Laser microdissectionCurrent protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.].  2015. 2015
2015 The presence of primary cilia in cancer cells does not predict responsiveness to modulation of smoothened activityInternational Journal of Oncology.  47:269-279. 2015
2015 Pedunculated focal nodular hyperplasia masquerading as perigastric mass identified by EUS-FNAGastrointestinal Endoscopy.  81:238-240. 2015
2014 Wnt5a suppresses tumor formation and redirects tumor phenotype in MMTV-Wnt1 tumorsPLoS ONE.  9. 2014
2014 Linking adiponectin and autophagy in the regulation of breast cancer metastasisThe Clinical investigator2014
2014 Intraductal papillary carcinoma of common bile duct diagnosed by endoscopic ultrasound-guided fine-needle aspirationEndoscopy.  46. 2014
2014 Linking adiponectin and autophagy in the regulation of breast cancer metastasisThe Clinical investigator.  92:1015-1023. 2014
2014 Primary pancreatic leiomyosarcoma: A rare diagnosis obtained by EUS-FNA cytologyGastrointestinal Endoscopy.  80:361-362. 2014
2013 The presence of a cytopathologist increases the diagnostic accuracy of endoscopic ultrasound-guided fine needle aspiration cytology for pancreatic adenocarcinoma: A meta-analysisCytopathology.  24:159-171. 2013
2012 Ubiquitous Brms1 expression is critical for mammary carcinoma metastasis suppression via promotion of apoptosisClinical and Experimental Metastasis.  29:315-325. 2012
2012 The influence of the cancer microenvironment on the process of metastasis.International Journal of Breast Cancer.  2012:756257. 2012
2011 ACAP4 protein cooperates with Grb2 protein to orchestrate epidermal growth factor-stimulated integrin β1 recycling in cell migrationJournal of Biological Chemistry.  286:43735-43747. 2011
2011 Targeting ErbB3-mediated stromal-epithelial interactions in pancreatic ductal adenocarcinomaBritish Journal of Cancer.  105:523-533. 2011
2011 Gli1 enhances migration and invasion via up-regulation of MMP-11 and promotes metastasis in ERα negative breast cancer cell linesClinical and Experimental Metastasis.  28:437-449. 2011
2010 Gli3 mediates cell survival and sensitivity to cyclopamine in pancreatic cancerCancer Biology and Therapy.  10:893-902. 2010
2010 Gli1 promotes cell survival and is predictive of a poor outcome in ERα-negative breast cancerBreast Cancer Research and Treatment.  123:59-71. 2010
2010 Northwestern profiling of potential translation-regulatory proteins in human breast epithelial cells and malignant breast tissues: evidence for pathological activation of the IGF1R IRESExperimental and Molecular Pathology.  88:341-352. 2010
2010 Primary cilia are decreased in breast cancer: Analysis of a collection of human breast cancer cell lines and tissuesJournal of Histochemistry and Cytochemistry.  58:857-870. 2010
2009 Dual effects of TGF-β On ERα-mediated estrogenic transcriptional activity in breast cancerMolecular Cancer.  8. 2009
2009 Epithelial transformation by KLF4 requires Notch1 but not canonical Notch1 signalingCancer Biology and Therapy.  8:1840-1851. 2009
2009 A shift from nuclear to cytoplasmic breast cancer metastasis suppressor 1 expression is associated with highly proliferative estrogen receptor-negative breast cancersTumor Biology.  30:148-159. 2009
2009 Loss of TGF-β or Wnt5a results in an increase in Wnt/β-catenin activity and redirects mammary tumour phenotypeBreast Cancer Research.  11. 2009
2009 Prevention of KLF4-mediated tumor initiation and malignant transformation by UAB30 rexinoidCancer Biology and Therapy.  8:289-298. 2009
2009 Prevention of KLF4-mediated tumor initiation and malignant transformation by UAB30 rexinoidCancer Biology and Therapy.  8:285-294. 2009
2009 Identification of molecular distinctions between normal breast-associated fibroblasts and breast cancer-associated fibroblastsCancer Microenvironment.  2:9-21. 2009
2008 Epigenetic silencing contributes to the loss of BRMS1 expression in breast cancerClinical and Experimental Metastasis.  25:753-763. 2008
2008 Sulfotransferase 2B1b in human breast: Differences in subcellular localization in African American and Caucasian womenJournal of Steroid Biochemistry and Molecular Biology.  111:171-177. 2008
2008 Vascular endothelial growth factor reduces tamoxifen efficacy and promotes metastatic colonization and desmoplasia in breast tumorsCancer Research.  68:6232-6240. 2008
2008 Fluorescent labeled anti-egfr antibody for identification of regional and distant metastasis in a preclinical xenograft modelHead & neck surgery.  30:782-789. 2008
2008 Immunohistochemical detection of EGFR, p185erbB-2, Bcl-2 and p53 in breast carcinomas in pre-menopausal and post-menopausal womenStain technology.  83:5-14. 2008
2007 Hedgehog pathway expression in heterogeneous pancreatic adenocarcinoma: Implications for the molecular analysis of clinically available biopsiesDiagnostic Molecular Pathology.  16:229-237. 2007
2007 Hedgehog signaling in mammary gland development and breast cancerJournal of Mammary Gland Biology and Neoplasia.  12:163-173. 2007
2007 Requirement of KISS1 secretion for multiple organ metastasis suppression and maintenance of tumor dormancyJNCI: Journal of the National Cancer Institute.  99:309-321. 2007
2007 Human breast fibroblasts inhibit growth of the MCF10AT xenograft model of proliferative breast diseaseAmerican Journal of Pathology.  170:1064-1076. 2007
2006 Human cytosolic sulfotransferase 2B1: Isoform expression, tissue specificity and subcellular localizationJournal of Steroid Biochemistry and Molecular Biology.  102:214-221. 2006
2006 Loss of breast cancer metastasis suppressor 1 protein expression predicts reduced disease-free survival in subsets of breast cancer patientsClinical Cancer Research.  12:6702-6708. 2006
2006 O-GlcNAc integrates the proteasome and transcriptome to regulate nuclear hormone receptorsMolecular and Cellular Biology.  26:8539-8550. 2006
2006 Validation of a five reagent immunohistochemistry assay for prognostication of estrogen-receptor expressing breast cancer.Journal of Clinical Oncology.  24:10081. 2006
2006 Osteopontin knockdown suppresses tumorigenicity of human metastatic breast carcinoma, MDA-MB-435Clinical and Experimental Metastasis.  23:123-133. 2006
2006 Kinetics of metastatic breast cancer cell trafficking in boneClinical Cancer Research.  12:1431-1440. 2006
2006 Hedgehog signaling and response to cyclopamine differ in epithelial and stromal cells in benign breast and breast cancerCancer Biology and Therapy.  5:674-683. 2006
2006 Multiple gene expression analyses in paraffin-embedded tissues by TaqMan low-density array. Application to Hedgehog and Wnt pathway analysis in ovarian endometrioid adenocarcinomaJournal of Molecular Diagnostics.  8:76-83. 2006
2006 Transforming growth factor-β signaling helps specify tumor type in DMBA and hormone-induced mammary cancersDifferentiation.  74:40-52. 2006
2005 Identification and immunohistochemical localization of Sulfotransferase 2B1b (SULT2B1b) in human lungBBA - General Subjects.  1724:119-126. 2005
2005 Hypersialylation of β 1 integrins, observed in colon adenocarcinoma, may contribute to cancer progression by up-regulating cell motilityCancer Research.  65:4645-4652. 2005
2005 Induction of KLF4 in basal keratinocytes blocks the proliferation- differentiation switch and initiates squamous epithelial dysplasiaOncogene.  24:1491-1500. 2005
2005 Optimal molecular profiling of tissue and tissue components: Defining the best processing and microdissection methods for biomedical applicationsMolecular Biotechnology.  29:119-152. 2005
2005 Breast fibroblasts modulate epithelial cell proliferation in three-dimensional in vitro co-culture.Breast Cancer Research.  7. 2005
2005 Cholangiocyte endothelin 1 and transforming growth factor β1 production in rat experimental hepatopulmonary syndromeGastroenterology.  129:682-695. 2005
2005 KLF4 and PCNA identify stages of tumor initiation in a conditional model of cutaneous squamous epithelial neoplasiaCancer Biology and Therapy.  4:1401-1408. 2005
2005 Optimal molecular profiling of tissue and tissue components: defining the best processing and microdissection methods for biomedical applications.Methods in Molecular Medicine.  103:15-66. 2005
2004 Different subcellular localization of sulphotransferase 2B1b in human placenta and prostateBiochemical Journal.  379:533-540. 2004
2004 Nuclear Localization of KLF4 Is Associated with An Aggressive Phenotype in Early-Stage Breast CancerClinical Cancer Research.  10:2709-2719. 2004
2004 Intratumor heterogeneity of biomarker expression in breast carcinomasStain technology.  79:25-36. 2004
2003 LIM kinase 1 is essential for the invasive growth of prostate epithelial cells: Implications in prostate cancerJournal of Biological Chemistry.  278:36868-36875. 2003
2003 Detecting the expression of human endogenous retrovirus E envelope transcripts in human prostate adenocarcinomaCancer.  98:187-197. 2003
2003 Risk biomarker assessment for breast cancer progression: Replication precision of nuclear morphometryAnalytical and Quantitative Cytology and Histology.  25:129-138. 2003
2003 Microvessel density and vascular endothelial growth factor expression in infiltrating lobular mammary carcinomaBreast Journal.  9:200-207. 2003
2003 Quantitation of HERV-K env gene expression and splicing in human breast cancerOncogene.  22:1528-1535. 2003
2003 Capecitabine induces rapid, sustained response in two patients with extensive oral verrucous carcinomaClinical Cancer Research.  9:580-585. 2003
2003 Race- and age-dependent alterations in global methylation of DNA in squamous cell carcinoma of the lung (United States)Cancer Causes and Control.  14:37-42. 2003
2003 Nuclear accumulation of p53 is a potential marker for the development of squamous cell lung cancer in smokersChest.  123:181-186. 2003
2002 Differential expression of growth factors in squamous cell carcinoma and precancerous lesions of the lungClinical Cancer Research.  8:734-744. 2002
2002 Down-regulation of Cdc6, a cell cycle regulatory gene, in prostate cancerJournal of Biological Chemistry.  277:25431-25438. 2002
2002 Hormone receptors and proliferation in breast carcinomas of equivalent histologic grades in pre- and postmenopausal womenInternational Journal of Cancer.  98:118-127. 2002
2002 Fine needle aspiration biopsy of the islet cell tumor of pancreas: A comparison between computerized axial tomography and endoscopic ultrasound-guided fine needle aspiration biopsyAnnals of Diagnostic Pathology.  6:106-112. 2002
2002 Microdissection of histologic sections: Past, present, and futureAdvances in Anatomic Pathology.  9:316-322. 2002
2001 Altered subcellular localization of Suppressin, a novel inhibitor of cell-cycle entry, is an independent prognostic factor in colorectal adenocarcinomasClinical Cancer Research.  7:3495-3503. 2001
2001 Laser capture microdissection.Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.].  Chapter 25:Unit-25A.1. 2001
2001 The spectrum of cytologic features in nonproliferative breast lesionsCancer.  93:140-145. 2001
2001 Altered global methylation of DNA: An epigenetic difference in susceptibility for lung cancer is associated with its progressionHuman Pathology.  32:856-862. 2001
2001 Expression of human endogenous retrovirus K envelope transcripts in human breast cancerClinical Cancer Research.  7:1553-1560. 2001
2001 Fatty acid synthase: An early molecular marker of progression of prostatic adenocarcinoma to androgen independenceJournal of Urology, The.  165:1027-1032. 2001
2001 Laser capture microdissection.Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.].  Chapter 25. 2001
2000 Increase of GKLF messenger RNA and protein expression during progression of breast cancerCancer Research.  60:6488-6495. 2000
2000 Methods of antigen recovery vary in their usefulness in unmasking specific antigens in immunohistochemistryApplied Immunohistochemistry and Molecular Morphology.  8:236-243. 2000
2000 Cytologic features of proliferative breast disease: A study designed to minimize sampling errorCancer.  90:33-40. 2000
2000 Changing trends in breast fine-needle aspiration: Results of the Papanicolaou Society of Cytopathology surveyDiagnostic Cytopathology.  22:126-130. 2000
2000 Immunohistochemical evaluation of global DNA methylation: Comparison with in vitro radiolabeled methyl incorporation assayStain technology.  75:251-258. 2000
2000 The expression of Ep-CAM (17-1A) in squamous cell cancers of the lungHuman Pathology.  31:482-487. 2000
2000 The expression of fatty acid synthase (FASE) is an early event in the development and progression of squamous cell carcinoma of the lungHuman Pathology.  31:1068-1073. 2000
1999 Changes in cyclin dependent kinase inhibitors p21 and p27 during the castration induced regression of the CWR22 model of prostatic adenocarcinomaJournal of Urology, The.  161:945-949. 1999
1998 The stability of estrogen and progesterone receptor expression on breast carcinoma cells stored as preservCyt suspensions and as ThinPrep slidesCancer.  84:355-360. 1998
1998 Detection of genital human papillomavirus and associated cytological abnormalities among college womenSexually Transmitted Diseases.  25:243-250. 1998
1998 Utility of thin-layer preparations in thyroid fine-needle aspiration: Diagnostic accuracy, cytomorphology, and optimal sample preparationCancer.  84:17-25. 1998
1998 Interobserver variability in the classification of proliferative breast lesions by fine-needle aspiration: results of the Papanicolaou Society of Cytopathology Study.Diagnostic Cytopathology.  18:150-165. 1998
1997 Can nonproliferative breast disease and proliferative breast disease without atypia be distinguished by fine-needle aspiration cytology?Cancer.  81:22-28. 1997
1997 Cytologic features of ductal and lobular carcinoma in fine needle aspirates of the breastActa Cytologica.  41:333-340. 1997
1996 Cytomorphology of cystic parathyroid lesions: report of four cases evaluated preoperatively by fine-needle aspiration.Diagnostic Cytopathology.  15:306-311. 1996
1996 DNA analysis and S-phase fraction determination by flow cytometric analysis of infiltrating lobular carcinoma of the breastModern Pathology.  9:930-937. 1996
1996 A rapid dual organ rat carcinogenesis bioassay for evaluating the chemoprevention of breast and colon cancer.Cancer Letters.  100:169-179. 1996
1996 The effect of dietary fat on the promotion of mammary and colon cancer in a dual-organ rat carcinogenesis modelNutrition and Cancer.  25:151-159. 1996
1995 An analysis of prognostic features in infiltrating lobular carcinoma of the breast.Modern Pathology.  8:830-836. 1995
1995 Inhibition of progression of aberrant crypt foci and colon tumor development by vitamin E and β-carotene in rats on a high-risk dietCancer Letters.  91:125-132. 1995
1995 Effect of suppressive therapy on thyroid fine needle aspiration cytology.Acta Cytologica.  39:402-408. 1995
1995 ACTH-producing pituitary carcinoma presenting as the cauda equina syndrome.Archives of Pathology and Laboratory Medicine.  119:93-96. 1995
1995 Effect of β-carotene and wheat bran fiber on colonic aberrant crypt and tumor formation in rats exposed to azoxymethane and high dietary fatCarcinogenesis.  16:127-132. 1995
1995 The significance of signet ring cells in infiltrating lobular carcinoma of the breastArchives of Pathology and Laboratory Medicine.  119:64-68. 1995
1994 Preoperative parathyroid localization: prospective evaluation of technetium 99m sestamibi.Otolaryngology - Head and Neck Surgery.  111:467-472. 1994
1994 A comparison of the usefulness of electron microscopy and immunohistochemistry. One laboratory's experience.Archives of Pathology and Laboratory Medicine.  118:922-926. 1994
1994 Ectopic breast cancer: case report and literature reviewSurgical Oncology.  3:295-304. 1994
1994 Retrospective analysis of non‐correlating cervical smears and colposcopically directed biopsiesDiagnostic Cytopathology.  11:343-347. 1994
1993 Potential synergism between wheat bran and psyllium: enhanced inhibition of colon cancerCancer Letters.  75:53-58. 1993
1992 "Signet Ring" sinus histiocytosis mimicking metastatic adenocarcinoma: report of two cases with immunohistochemical and ultrastructural study.Modern Pathology.  5:497-500. 1992
1991 The bone marrow in human immunodeficiency virus (HIV)-related disease. Morphology and clinical correlation.American Journal of Clinical Pathology.  95:63-71. 1991


Year Title Altmetric
2006 Biology of breast cancer: Molecular and pathologic features of ductal neoplasia of the breast: Racial considerations.  39-70. 2006

Education And Training

  • Doctor of Medicine, University of Alabama 1985
  • George Washington University Hospital, Residency 1989
  • George Washington University Hospital, Postdoctoral Fellowship 1990
  • Full Name

  • Andra Frost