Selected Publications

Academic Article

Year Title Altmetric
2018 Acetylation of ACAP4 regulates CCL18-elicited breast cancer cell migration and invasion.Journal of Molecular Cell Biology.  10:559-572. 2018
2017 Methods to Evaluate Cell Growth, Viability, and Response to Treatment in a Tissue Engineered Breast Cancer Model.Scientific Reports.  7:14167. 2017
2017 Silencing of TGF-β1 in tumor cells impacts MMP-9 in tumor microenvironment.Scientific Reports.  7:8678. 2017
2016 Computational and Experimental Analysis of Fluid Transport Through Three-Dimensional Collagen-Matrigel Hydrogels.Annals of Biomedical Engineering.  45:1027-1038. 2016
2016 A recapitulative three-dimensional model of breast carcinoma requires perfusion for multi-week growth.Journal of Tissue Engineering.  7:2041731416660739. 2016
2015 Laser Microdissection.Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.].  112:25A.1.1-25A.130. 2015
2015 The presence of primary cilia in cancer cells does not predict responsiveness to modulation of smoothened activity.International Journal of Oncology.  47:269-279. 2015
2015 Flow-perfusion bioreactor system for engineered breast cancer surrogates to be used in preclinical testing.Journal of Tissue Engineering and Regenerative Medicine.  11:1242-1250. 2015
2015 Pedunculated focal nodular hyperplasia masquerading as perigastric mass identified by EUS-FNA.Gastrointestinal Endoscopy.  81:238-239. 2015
2014 Linking adiponectin and autophagy in the regulation of breast cancer metastasis.The Clinical investigator.  92:1015-1023. 2014
2014 Primary pancreatic leiomyosarcoma: a rare diagnosis obtained by EUS-FNA cytology.Gastrointestinal Endoscopy.  80:361-362. 2014
2014 Intraductal papillary carcinoma of common bile duct diagnosed by endoscopic ultrasound-guided fine-needle aspiration.Endoscopy.  46 Suppl 1 UCTN:E248-E249. 2014
2014 Linking adiponectin and autophagy in the regulation of breast cancer metastasisThe Clinical investigator.  92:1015-1023. 2014
2014 Wnt5a suppresses tumor formation and redirects tumor phenotype in MMTV-Wnt1 tumors.PLoS ONE.  9:e113247. 2014
2013 The presence of a cytopathologist increases the diagnostic accuracy of endoscopic ultrasound-guided fine needle aspiration cytology for pancreatic adenocarcinoma: a meta-analysis.Cytopathology.  24:159-171. 2013
2012 Ubiquitous Brms1 expression is critical for mammary carcinoma metastasis suppression via promotion of apoptosis.Clinical and Experimental Metastasis.  29:315-325. 2012
2012 The influence of the cancer microenvironment on the process of metastasis.International Journal of Breast Cancer.  2012:756257. 2012
2011 ACAP4 protein cooperates with Grb2 protein to orchestrate epidermal growth factor-stimulated integrin β1 recycling in cell migration.Journal of Biological Chemistry.  286:43735-43747. 2011
2011 Targeting ErbB3-mediated stromal-epithelial interactions in pancreatic ductal adenocarcinoma.British Journal of Cancer.  105:523-533. 2011
2011 Gli1 enhances migration and invasion via up-regulation of MMP-11 and promotes metastasis in ERα negative breast cancer cell lines.Clinical and Experimental Metastasis.  28:437-449. 2011
2010 Gli3 mediates cell survival and sensitivity to cyclopamine in pancreatic cancer.Cancer Biology and Therapy.  10:893-902. 2010
2010 Primary cilia are decreased in breast cancer: analysis of a collection of human breast cancer cell lines and tissues.Journal of Histochemistry and Cytochemistry.  58:857-870. 2010
2010 Gli1 promotes cell survival and is predictive of a poor outcome in ERalpha-negative breast cancer.Breast Cancer Research and Treatment.  123:59-71. 2010
2010 Northwestern profiling of potential translation-regulatory proteins in human breast epithelial cells and malignant breast tissues: evidence for pathological activation of the IGF1R IRES.Experimental and Molecular Pathology.  88:341-352. 2010
2009 Identification of molecular distinctions between normal breast-associated fibroblasts and breast cancer-associated fibroblasts.Cancer Microenvironment.  2:9-21. 2009
2009 Dual effects of TGF-beta on ERalpha-mediated estrogenic transcriptional activity in breast cancer.Molecular Cancer.  8:111. 2009
2009 Epithelial transformation by KLF4 requires Notch1 but not canonical Notch1 signaling.Cancer Biology and Therapy.  8:1840-1851. 2009
2009 Prevention of KLF4-mediated tumor initiation and malignant transformation by UAB30 rexinoidCancer Biology and Therapy.  8:285-294. 2009
2009 Prevention of KLF4-mediated tumor initiation and malignant transformation by UAB30 rexinoid.Cancer Biology and Therapy.  8:289-298. 2009
2009 A shift from nuclear to cytoplasmic breast cancer metastasis suppressor 1 expression is associated with highly proliferative estrogen receptor-negative breast cancers.Tumor Biology.  30:148-159. 2009
2009 Loss of TGF-beta or Wnt5a results in an increase in Wnt/beta-catenin activity and redirects mammary tumour phenotype.Breast Cancer Research.  11:R19. 2009
2008 Sulfotransferase 2B1b in human breast: differences in subcellular localization in African American and Caucasian women.Journal of Steroid Biochemistry and Molecular Biology.  111:171-177. 2008
2008 Vascular endothelial growth factor reduces tamoxifen efficacy and promotes metastatic colonization and desmoplasia in breast tumors.Cancer Research.  68:6232-6240. 2008
2008 Fluorescent labeled anti-EGFR antibody for identification of regional and distant metastasis in a preclinical xenograft model.Head & neck surgery.  30:782-789. 2008
2008 Immunohistochemical detection of EGFR, p185(erbB-2), Bcl-2 and p53 in breast carcinomas in pre-menopausal and post-menopausal women.Stain technology.  83:5-14. 2008
2008 Epigenetic silencing contributes to the loss of BRMS1 expression in breast cancer.Clinical and Experimental Metastasis.  25:753-763. 2008
2007 Hedgehog pathway expression in heterogeneous pancreatic adenocarcinoma: implications for the molecular analysis of clinically available biopsies.Diagnostic Molecular Pathology.  16:229-237. 2007
2007 Hedgehog signaling in mammary gland development and breast cancer.Journal of Mammary Gland Biology and Neoplasia.  12:163-173. 2007
2007 Human breast fibroblasts inhibit growth of the MCF10AT xenograft model of proliferative breast disease.American Journal of Pathology.  170:1064-1076. 2007
2007 Requirement of KISS1 secretion for multiple organ metastasis suppression and maintenance of tumor dormancy.JNCI: Journal of the National Cancer Institute.  99:309-321. 2007
2006 Human cytosolic sulfotransferase 2B1: isoform expression, tissue specificity and subcellular localization.Journal of Steroid Biochemistry and Molecular Biology.  102:214-221. 2006
2006 Loss of breast cancer metastasis suppressor 1 protein expression predicts reduced disease-free survival in subsets of breast cancer patients.Clinical Cancer Research.  12:6702-6708. 2006
2006 O-GlcNAc integrates the proteasome and transcriptome to regulate nuclear hormone receptors.Molecular and Cellular Biology.  26:8539-8550. 2006
2006 Validation of a five reagent immunohistochemistry assay for prognostication of estrogen-receptor expressing breast cancer.Journal of Clinical Oncology.  24:10081. 2006
2006 Hedgehog signaling and response to cyclopamine differ in epithelial and stromal cells in benign breast and breast cancer.Cancer Biology and Therapy.  5:674-683. 2006
2006 Kinetics of metastatic breast cancer cell trafficking in bone.Clinical Cancer Research.  12:1431-1440. 2006
2006 Multiple gene expression analyses in paraffin-embedded tissues by TaqMan low-density array: Application to hedgehog and Wnt pathway analysis in ovarian endometrioid adenocarcinoma.Journal of Molecular Diagnostics.  8:76-83. 2006
2006 Transforming growth factor-beta signaling helps specify tumor type in DMBA and hormone-induced mammary cancers.Differentiation.  74:40-52. 2006
2006 Osteopontin knockdown suppresses tumorigenicity of human metastatic breast carcinoma, MDA-MB-435.Clinical and Experimental Metastasis.  23:123-133. 2006
2005 KLF4 and PCNA identify stages of tumor initiation in a conditional model of cutaneous squamous epithelial neoplasia.Cancer Biology and Therapy.  4:1401-1408. 2005
2005 Cholangiocyte endothelin 1 and transforming growth factor beta1 production in rat experimental hepatopulmonary syndrome.Gastroenterology.  129:682-695. 2005
2005 Identification and immunohistochemical localization of Sulfotransferase 2B1b (SULT2B1b) in human lung.BBA - Biochimica et Biophysica Acta.  1724:119-126. 2005
2005 Hypersialylation of beta1 integrins, observed in colon adenocarcinoma, may contribute to cancer progression by up-regulating cell motility.Cancer Research.  65:4645-4652. 2005
2005 Induction of KLF4 in basal keratinocytes blocks the proliferation-differentiation switch and initiates squamous epithelial dysplasia.Oncogene.  24:1491-1500. 2005
2005 Optimal molecular profiling of tissue and tissue components: defining the best processing and microdissection methods for biomedical applications.Molecular Biotechnology.  29:119-152. 2005
2005 Breast fibroblasts modulate epithelial cell proliferation in three-dimensional in vitro co-culture.Breast Cancer Research.  7:R46-R59. 2005
2005 Optimal molecular profiling of tissue and tissue components: defining the best processing and microdissection methods for biomedical applications.Methods in Molecular Medicine.  103:15-66. 2005
2004 Different subcellular localization of sulphotransferase 2B1b in human placenta and prostate.Biochemical Journal.  379:533-540. 2004
2004 Nuclear localization of KLF4 is associated with an aggressive phenotype in early-stage breast cancer.Clinical Cancer Research.  10:2709-2719. 2004
2004 Intratumor heterogeneity of biomarker expression in breast carcinomas.Stain technology.  79:25-36. 2004
2003 LIM kinase 1 is essential for the invasive growth of prostate epithelial cells: implications in prostate cancer.Journal of Biological Chemistry.  278:36868-36875. 2003
2003 Detecting the expression of human endogenous retrovirus E envelope transcripts in human prostate adenocarcinoma.Cancer.  98:187-197. 2003
2003 Microvessel density and vascular endothelial growth factor expression in infiltrating lobular mammary carcinoma.Breast Journal.  9:200-207. 2003
2003 Quantitation of HERV-K env gene expression and splicing in human breast cancer.Oncogene.  22:1528-1535. 2003
2003 Capecitabine induces rapid, sustained response in two patients with extensive oral verrucous carcinoma.Clinical Cancer Research.  9:580-585. 2003
2003 Race- and age-dependent alterations in global methylation of DNA in squamous cell carcinoma of the lung (United States).Cancer Causes and Control.  14:37-42. 2003
2003 Nuclear accumulation of p53 is a potential marker for the development of squamous cell lung cancer in smokers.Chest.  123:181-186. 2003
2003 Risk biomarker assessment for breast cancer progression: replication precision of nuclear morphometry.Analytical and Quantitative Cytology and Histology.  25:129-138. 2003
2002 Microdissection of histologic sections: past, present, and future.Advances in Anatomic Pathology.  9:316-322. 2002
2002 Down-regulation of Cdc6, a cell cycle regulatory gene, in prostate cancer.Journal of Biological Chemistry.  277:25431-25438. 2002
2002 Fine needle aspiration biopsy of the islet cell tumor of pancreas: a comparison between computerized axial tomography and endoscopic ultrasound-guided fine needle aspiration biopsy.Annals of Diagnostic Pathology.  6:106-112. 2002
2002 Differential expression of growth factors in squamous cell carcinoma and precancerous lesions of the lung.Clinical Cancer Research.  8:734-744. 2002
2002 Hormone receptors and proliferation in breast carcinomas of equivalent histologic grades in pre- and postmenopausal women.International Journal of Cancer.  98:118-127. 2002
2001 Altered subcellular localization of suppressin, a novel inhibitor of cell-cycle entry, is an independent prognostic factor in colorectal adenocarcinomas.Clinical Cancer Research.  7:3495-3503. 2001
2001 Altered global methylation of DNA: an epigenetic difference in susceptibility for lung cancer is associated with its progression.Human Pathology.  32:856-862. 2001
2001 Laser capture microdissection.Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.].  Chapter 25:Unit-25A.1. 2001
2001 Expression of human endogenous retrovirus k envelope transcripts in human breast cancer.Clinical Cancer Research.  7:1553-1560. 2001
2001 The spectrum of cytologic features in nonproliferative breast lesions.Cancer.  93:140-145. 2001
2001 Fatty acid synthase: an early molecular marker of progression of prostatic adenocarcinoma to androgen independence.Journal of Urology, The.  165:1027-1032. 2001
2000 Increase of GKLF messenger RNA and protein expression during progression of breast cancer.Cancer Research.  60:6488-6495. 2000
2000 Immunohistochemical evaluation of global DNA methylation: comparison with in vitro radiolabeled methyl incorporation assay.Stain technology.  75:251-258. 2000
2000 Methods of antigen recovery vary in their usefulness in unmasking specific antigens in immunohistochemistry.Applied Immunohistochemistry and Molecular Morphology.  8:236-243. 2000
2000 The expression of fatty acid synthase (FASE) is an early event in the development and progression of squamous cell carcinoma of the lung.Human Pathology.  31:1068-1073. 2000
2000 The expression of Ep-CAM (17-1A) in squamous cell cancers of the lung.Human Pathology.  31:482-487. 2000
2000 Cytologic features of proliferative breast disease: a study designed to minimize sampling error.Cancer.  90:33-40. 2000
2000 Changing trends in breast fine-needle aspiration: results of the Papanicolaou Society of Cytopathology Survey.Diagnostic Cytopathology.  22:126-130. 2000
1999 Changes in cyclin dependent kinase inhibitors p21 and p27 during the castration induced regression of the CWR22 model of prostatic adenocarcinoma.Journal of Urology, The.  161:945-949. 1999
1998 The stability of estrogen and progesterone receptor expression on breast carcinoma cells stored as PreservCyt suspensions and as ThinPrep slides.Cancer.  84:355-360. 1998
1998 Detection of genital human papillomavirus and associated cytological abnormalities among college women.Sexually Transmitted Diseases.  25:243-250. 1998
1998 Utility of thin-layer preparations in thyroid fine-needle aspiration: diagnostic accuracy, cytomorphology, and optimal sample preparation.Cancer.  84:17-25. 1998
1998 Interobserver variability in the classification of proliferative breast lesions by fine-needle aspiration: results of the Papanicolaou Society of Cytopathology Study.Diagnostic Cytopathology.  18:150-165. 1998
1997 Cytologic features of ductal and lobular carcinoma in fine needle aspirates of the breast.Acta Cytologica.  41:333-340. 1997
1997 Can nonproliferative breast disease and proliferative breast disease without atypia be distinguished by fine-needle aspiration cytology?Cancer.  81:22-28. 1997
1996 Laser capture microdissection.Science.  274:998-1001. 1996
1996 Cytomorphology of cystic parathyroid lesions: report of four cases evaluated preoperatively by fine-needle aspiration.Diagnostic Cytopathology.  15:306-311. 1996
1996 DNA analysis and S-phase fraction determination by flow cytometric analysis of infiltrating lobular carcinoma of the breast.Modern Pathology.  9:930-937. 1996
1996 A rapid dual organ rat carcinogenesis bioassay for evaluating the chemoprevention of breast and colon cancer.Cancer Letters.  100:169-179. 1996
1996 The effect of dietary fat on the promotion of mammary and colon cancer in a dual-organ rat carcinogenesis model.Nutrition and Cancer.  25:151-159. 1996
1995 An analysis of prognostic features in infiltrating lobular carcinoma of the breast.Modern Pathology.  8:830-836. 1995
1995 Inhibition of progression of aberrant crypt foci and colon tumor development by vitamin E and beta-carotene in rats on a high-risk diet.Cancer Letters.  91:125-132. 1995
1995 Effect of suppressive therapy on thyroid fine needle aspiration cytology.Acta Cytologica.  39:402-408. 1995
1995 ACTH-producing pituitary carcinoma presenting as the cauda equina syndrome.Archives of Pathology and Laboratory Medicine.  119:93-96. 1995
1995 Effect of beta-carotene and wheat bran fiber on colonic aberrant crypt and tumor formation in rats exposed to azoxymethane and high dietary fat.Carcinogenesis.  16:127-132. 1995
1995 The significance of signet ring cells in infiltrating lobular carcinoma of the breast.Archives of Pathology and Laboratory Medicine.  119:64-68. 1995
1994 Retrospective analysis of non-correlating cervical smears and colposcopically directed biopsies.Diagnostic Cytopathology.  11:343-347. 1994
1994 Ectopic breast cancer: case report and literature review.Surgical Oncology.  3:295-304. 1994
1994 Preoperative parathyroid localization: prospective evaluation of technetium 99m sestamibi.Otolaryngology - Head and Neck Surgery.  111:467-472. 1994
1994 A comparison of the usefulness of electron microscopy and immunohistochemistry. One laboratory's experience.Archives of Pathology and Laboratory Medicine.  118:922-926. 1994
1993 Potential synergism between wheat bran and psyllium: enhanced inhibition of colon cancer.Cancer Letters.  75:53-58. 1993
1992 "Signet Ring" sinus histiocytosis mimicking metastatic adenocarcinoma: report of two cases with immunohistochemical and ultrastructural study.Modern Pathology.  5:497-500. 1992
1991 The bone marrow in human immunodeficiency virus (HIV)-related disease. Morphology and clinical correlation.American Journal of Clinical Pathology.  95:63-71. 1991
Preparation and Analysis of In Vitro Three Dimensional Breast Carcinoma Surrogates.Journal of Visualized Experiments


Year Title Altmetric
2006 Biology of breast cancer: Molecular and pathologic features of ductal neoplasia of the breast: Racial considerations.  39-70. 2006

Education And Training

  • Doctor of Medicine, University of Alabama
  • George Washington University Hospital, Residency 1989
  • George Washington University Hospital, Postdoctoral Fellowship 1990
  • Full Name

  • Andra Frost
  • Blazerid

  • afrost